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      Plasma Testosterone in Prepubertal Cryptorchid Boys under Long-Term HCG Therapy

      , ,

      Hormone Research in Paediatrics

      S. Karger AG

      Cryptorchidism, HCG treatment, Testosterone response

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          Abstract

          Plasma testosterone concentrations were determined before and after 6 weeks of human chorionic gonadotropin treatment in 36 prepubertal boys with bilateral or unilateral cryptorchidism. Mean ± SD basal and post-treatment values (ng/l00 ml) in the bilateral group were: treatment successful (n = 14): 32 ± 19 and 302 ± 49, treatment unsuccessful (n = 12): 20 ± 15 and 176 ± 73. The figures for the unilateral group were: treatment successful (n = 6): 23 ± 9 and 244 ± 41, treatment unsuccessful (n = 5): 22 ± 11 and 264 ± 102. In the bilateral group significant differences in the T response emerged when successfully treated boys were compared to unsuccessfully treated ones. It is concluded that Leydig cell function may be impaired in some cases of cryptorchidism.

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          Author and article information

          Journal
          HRE
          Horm Res Paediatr
          10.1159/issn.1663-2818
          Hormone Research in Paediatrics
          S. Karger AG
          1663-2818
          1663-2826
          1976
          1976
          21 November 2008
          : 7
          : 2
          : 77-82
          Affiliations
          Department of Diagnostic Endocrinology, University Children’s Hospital, University of Tübingen, Tübingen
          Article
          178714 Horm Res 1976;7:77–82
          10.1159/000178714
          12073
          © 1976 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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          Pages: 6
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