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      Plasma Testosterone in Prepubertal Cryptorchid Boys under Long-Term HCG Therapy

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      Hormone Research in Paediatrics

      S. Karger AG

      Cryptorchidism, HCG treatment, Testosterone response

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          Plasma testosterone concentrations were determined before and after 6 weeks of human chorionic gonadotropin treatment in 36 prepubertal boys with bilateral or unilateral cryptorchidism. Mean ± SD basal and post-treatment values (ng/l00 ml) in the bilateral group were: treatment successful (n = 14): 32 ± 19 and 302 ± 49, treatment unsuccessful (n = 12): 20 ± 15 and 176 ± 73. The figures for the unilateral group were: treatment successful (n = 6): 23 ± 9 and 244 ± 41, treatment unsuccessful (n = 5): 22 ± 11 and 264 ± 102. In the bilateral group significant differences in the T response emerged when successfully treated boys were compared to unsuccessfully treated ones. It is concluded that Leydig cell function may be impaired in some cases of cryptorchidism.

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          Author and article information

          Horm Res Paediatr
          Hormone Research in Paediatrics
          S. Karger AG
          21 November 2008
          : 7
          : 2
          : 77-82
          Department of Diagnostic Endocrinology, University Children’s Hospital, University of Tübingen, Tübingen
          178714 Horm Res 1976;7:77–82
          © 1976 S. Karger AG, Basel

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          Pages: 6


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