Evaluation of role of HPLC (Merits &amp; Pitfalls), in the diagnosis of various hemoglobinopathies &amp; thalassemic syndromes.

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Abstract

: HPLC is one of the most important tools for accurate diagnosis of hemoglobinopathies and thalassemias. The advantage of the HPLC system is the excellent resolution, reproducibility &quantification of several normal and abnormal hemoglobin.

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Journal ID (iso-abbrev): Indian J Pathol Microbiol

Title: Indian journal of pathology & microbiology

Publisher: Medknow

ISSN (Electronic): 0974-5130

ISSN (Print): 0377-4929

Publication date (Electronic): 2021

Volume: 64

Issue: 3

Affiliations

[1 ] Specialist Hematologist, Department of Hematology, MMCH (Tertiary Care Hospital and Thalassemia Referral Centre), Madinah Munawarah, KSA.

[2 ] Prof. and Head Department of Anatomy LUC Malaysia, MMCH (Tertiary Care Hospital and Thalassemia Referral Centre), Madinah Munawarah, KSA.

[3 ] Head Cytogenetics, MMCH (Tertiary Care Hospital and Thalassemia Referral Centre), Madinah Munawarah, KSA.

[4 ] Prof. Cytogenetic Department, MMCH (Tertiary Care Hospital and Thalassemia Referral Centre), Madinah Munawarah, KSA.

[5 ] Laboratory Head and Director, MMCH (Tertiary Care Hospital and Thalassemia Referral Centre), Madinah Munawarah, KSA.

[6 ] Deputy Lab. Director, MMCH (Tertiary Care Hospital and Thalassemia Referral Centre), Madinah Munawarah, KSA.

[7 ] Supervisor Laboratory, MMCH (Tertiary Care Hospital and Thalassemia Referral Centre), Madinah Munawarah, KSA.

[8 ] Senior Staff, Department of Special Chemistry, MMCH (Tertiary Care Hospital and Thalassemia Referral Centre), Madinah Munawarah, KSA.

Article

Publisher Item ID: IndianJPatholMicrobiol_2021_64_3_518_322415

DOI: 10.4103/IJPM.IJPM_709_20

PubMed ID: 34341263

SO-VID: d1c6a2ab-ea28-45ff-9e32-4dae7c61c461

History

Keywords: thalassemia,sickling test,High-performance liquid chromatography,Hemoglobinopathies

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Keywords: thalassemia, sickling test, High-performance liquid chromatography, Hemoglobinopathies

Evaluation of role of HPLC (Merits & Pitfalls), in the diagnosis of various hemoglobinopathies & thalassemic syndromes.

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