High-dose oral amoxicillin plus probenecid is highly effective for syphilis in patients with HIV infection.

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Abstract

Intramuscular benzathine penicillin G (BPG) is widely used for the treatment of syphilis. However, BPG is not available in some countries. This study examined the effectiveness and safety of high-dose oral amoxicillin plus probenecid for the treatment of syphilis in patients with human immunodeficiency virus type 1 (HIV-1).

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Author and article information

Journal

Journal ID (iso-abbrev): Clin. Infect. Dis.

Title: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 1537-6591

ISSN (Print): 1058-4838

Publication date (Electronic): Jul 15 2015

Volume: 61

Issue: 2

Affiliations

[1 ] AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo.

[2 ] AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo Center for AIDS Research, Kumamoto University, Japan.

Article

Publisher Item ID: civ270

DOI: 10.1093/cid/civ270

PubMed ID: 25829004

SO-VID: d1f1d6c5-a805-4a45-9a08-09e7ceca90e7

History

Keywords: HIV,MSM,amoxicillin,syphilis,treatment

Data availability:

Keywords: HIV, MSM, amoxicillin, syphilis, treatment

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