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      Unwarranted Variation in the Quality of Care for Patients With Diseases of the Thoracic Aorta

      research-article
      , MSc, PhD 1 , , MD, PhD 2 , , , MA 3 , , MD 4 , , MD 2 , , MD 2 , , MD, MRCS, PhD 5 , , FFPH 1 , , BSc, MBBS, FRCS, MS 6 , , FRCS 7 , , MD, FRCS 2 , the UK Aortic Forum , , , , , , , ,
      Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
      John Wiley and Sons Inc.
      aortic disease, aortic dissection, cardiac surgery, quality of care, Health Services, Mortality/Survival, Quality and Outcomes

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          Abstract

          Background

          Thoracic aortic disease has a high mortality. We sought to establish the contribution of unwarranted variation in care to regional differences in outcomes observed in patients with thoracic aortic disease in England.

          Methods and Results

          Data from the Hospital Episode Statistics ( HES) and the National Adult Cardiac Surgery Audit ( NACSA) were extracted. A parallel systematic review/meta‐analysis through December 2015, and structure and process questionnaire of English cardiac surgery units were also accomplished. Treatment and mortality rates were investigated. A total of 24 548 adult patients in the HES study, 8058 in the NACSA study, and 103 543 from a total of 33 studies in the systematic review were obtained. Treatment rates for thoracic aortic disease within 6 months of index admission ranged from 7.6% to 31.5% between English counties. Risk‐adjusted 6‐month mortality in untreated patients ranged from 19.4% to 36.3%. Regional variation persisted after adjustment for disease or patient factors. Regional cardiac units with higher case volumes treated more‐complex patients and had significantly lower risk‐adjusted mortality relative to low‐volume units. The results of the systematic review indicated that the delivery of care by multidisciplinary teams in high‐volume units resulted in better outcomes. The observational analyses and the online survey indicated that this is not how services are configured in most units in England.

          Conclusions

          Changes in the organization of services that address unwarranted variation in the provision of care for patients with thoracic aortic disease in England may result in more‐equitable access to treatment and improved outcomes.

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          Most cited references54

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          2010 ACCF/AHA/AATS/ACR/ASA/SCA/SCAI/SIR/STS/SVM Guidelines for the diagnosis and management of patients with thoracic aortic disease. A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology,American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of Thoracic Surgeons,and Society for Vascular Medicine.

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            Canadian Cardiovascular Society position statement on the management of thoracic aortic disease.

            This Canadian Cardiovascular Society position statement aims to provide succinct perspectives on key issues in the management of thoracic aortic disease (TAD). This document is not a comprehensive overview of TAD and important elements of the epidemiology, presentation, diagnosis, and management of acute aortic syndromes are deliberately not discussed; readers are referred to the 2010 guidelines published by the American Heart Association, American College of Cardiology, American Association for Thoracic Surgery, and other stakeholders. Rather, this document is a practical guide for clinicians managing adult patients with TAD. Topics covered include size thresholds for surgical intervention, emerging therapies, imaging modalities, medical and lifestyle management, and genetics of TAD. The primary panel consisted of experts from a variety of disciplines that are essential for comprehensive management of TAD patients. The methodology involved a focused literature review with an emphasis on updates since 2010 and the use of Grading of Recommendations Assessment, Development, and Evaluation methodology to arrive at specific recommendations. The final document then underwent review by a secondary panel. This document aims to provide recommendations for most patients and situations. However, the ultimate judgement regarding the management of any individual patients should be made by their health care team.
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              The IRAD classification system for characterizing survival after aortic dissection.

              The classification of aortic dissection into acute ( 30 days). Overall survival was progressively lower through the 4 time periods. This IRAD classification system can provide clinicians with a more robust method of characterizing survival after aortic dissection over time than previous methods. This system will be useful for treating patients, counseling patients and families, and studying new diagnostic and treatment methods. Copyright © 2013 Elsevier Inc. All rights reserved.
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                Author and article information

                Contributors
                gm247@le.ac.uk
                Journal
                J Am Heart Assoc
                J Am Heart Assoc
                10.1002/(ISSN)2047-9980
                JAH3
                ahaoa
                Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
                John Wiley and Sons Inc. (Hoboken )
                2047-9980
                14 March 2017
                March 2017
                : 6
                : 3 ( doiID: 10.1002/jah3.2017.6.issue-3 )
                : e004913
                Affiliations
                [ 1 ] Dr Foster Unit Department of Primary Care and Public Health School of Public Health Imperial College London United Kingdom
                [ 2 ] Leicester Cardiovascular Biomedical Research Unit & Department of Cardiovascular Sciences Glenfield Hospital University of Leicester United Kingdom
                [ 3 ] Information Department Liverpool Heart and Chest Hospital Liverpool United Kingdom
                [ 4 ] School of Clinical Sciences Bristol Heart Institute University of Bristol United Kingdom
                [ 5 ] Department of Health Economics University of Liverpool United Kingdom
                [ 6 ] Department of Cardiothoracic Surgery Papworth Hospital Cambridge United Kingdom
                [ 7 ] Department of Cardiothoracic Surgery Liverpool Heart and Chest Hospital Liverpool United Kingdom
                Author notes
                [*] [* ] Correspondence to: Giovanni Mariscalco, MD, PhD, Leicester Cardiovascular Biomedical Research Unit & Department of Cardiovascular Sciences, Clinical Science Wing, Glenfield Hospital, University of Leicester, Groby Road, Leicester LE39QP, United Kingdom. E‐mail: gm247@ 123456le.ac.uk
                [†]

                Dr Bottle and Dr Mariscalco contributed equally to this work.

                [‡]

                A complete list of the UK Aortic Forum Collaborators can be found in the Appendix at the end of the article.

                Article
                JAH32100
                10.1161/JAHA.116.004913
                5524021
                28292748
                d52be128-479d-486f-8fad-25398491cc73
                © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

                This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

                History
                : 08 November 2016
                : 07 February 2017
                Page count
                Figures: 4, Tables: 4, Pages: 66, Words: 10848
                Funding
                Funded by: Leicester NIHR Cardiovascular Biomedical Research Units
                Funded by: British Heart Foundation
                Funded by: Dr Foster
                Funded by: National Institute for Health Research (NIHR) Health Services Research
                Funded by: NIHR Biomedical Research Centre
                Categories
                Original Research
                Original Research
                Cardiovascular Surgery
                Custom metadata
                2.0
                jah32100
                March 2017
                Converter:WILEY_ML3GV2_TO_NLMPMC version:5.1.3 mode:remove_FC converted:11.07.2017

                Cardiovascular Medicine
                aortic disease,aortic dissection,cardiac surgery,quality of care,health services,mortality/survival,quality and outcomes

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