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      Nonmelanoma Skin Cancer

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          Abstract

          Nonmelanoma skin cancer (NMSC) represents the most common form of cancer in Caucasians, with continuing increase in incidence worldwide. Basal cell carcinoma (BCC) accounts for 75% of cases of NMSC, and squamous cell carcinoma (SCC) accounts for the remaining majority of NMSC cases. Whilst metastasis from BCC is extremely rare, metastasis from high-risk SCC may be fatal. In this article, we review the aetiology, diagnosis and management of NMSC.

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          Skin cancers after organ transplantation.

          Sylvie Euvrard, Jean Kanitakis, Alain Claudy (2003)
          Article 0 comments Cited 262 times – based on 0 reviews     Review now
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            Human homolog of patched, a candidate gene for the basal cell nevus syndrome.

            Keven R. Johnson, Teresa A. Myers, Marcia Epstein … (1996)
            The basal cell nevus syndrome (BCNS) is characterized by developmental abnormalities and by the postnatal occurrence of cancers, especially basal cell carcinomas (BCCs), the most common human cancer. Heritable mutations in BCNS patients and a somatic mutation in a sporadic BCC were identified in a human homolog of the Drosophila patched (ptc) gene. The ptc gene encodes a transmembrane protein that in Drosophila acts in opposition to the Hedgehog signaling protein, controlling cell fates, patterning, and growth in numerous tissues. The human PTC gene appears to be crucial for proper embryonic development and for tumor suppression.
            Article 0 comments Cited 154 times – based on 0 reviews     Review now
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              Guidelines for the management of basal cell carcinoma.

              William Telfer, G B Colver, … (2008)
              This article represents a planned regular updating of the previous British Association of Dermatologists guidelines for the management of basal cell carcinoma. These guidelines present evidence-based guidance for treatment, with identification of the strength of evidence available at the time of preparation of the guidelines, and a brief overview of epidemiological aspects, diagnosis and investigation.
              Article 0 comments Cited 133 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): J Cutan Aesthet Surg
                Journal ID (iso-abbrev): J Cutan Aesthet Surg
                Journal ID (publisher-id): JCAS
                Title: Journal of Cutaneous and Aesthetic Surgery
                Publisher: Medknow Publications & Media Pvt Ltd (India )
                ISSN (Print): 0974-2077
                ISSN (Electronic): 0974-5157
                Publication date (Print): Jan-Mar 2012
                Volume: 5
                Issue: 1
                Pages: 3-10
                Affiliations
                [1] Dermatology Centre, Salford Royal Hospital, NHS Foundation Trust, Stott Lane, Salford M6 8HD, UK
                Author notes
                Address for correspondence: Dr. Venura Samarasinghe, Dermatology Centre, Salford Royal Hospital NHS Foundation Trust, Stott Lane, Salford M6 8HD, UK. E-mail: venuras1@ 123456hotmail.com
                Article
                Publisher ID: JCAS-5-3
                DOI: 10.4103/0974-2077.94323
                PMC ID: 3339125
                PubMed ID: 22557848
                SO-VID: d71122b4-8813-442a-9d70-2cacdca68de3
                Copyright © Copyright: © Journal of Cutaneous and Aesthetic Surgery
                License:

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Categories
                Subject: Review Article

                ScienceOpen disciplines: Surgery
                Keywords: nonmelanoma skin cancer,squamous cell carcinoma,basal cell carcinoma
                Data availability:
                ScienceOpen disciplines: Surgery
                Keywords: nonmelanoma skin cancer, squamous cell carcinoma, basal cell carcinoma

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