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      Frequency and clinical impact of WT1 mutations in the context of CEBPA-mutated acute myeloid leukemia.

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          Abstract

          Several studies have confirmed that mutations in the Wilms tumor 1 (WT1) gene occur in adult acute myeloid leukemia (AML). However, few data are available regarding the incidence of WT1 mutations in CEBPAmut AML and their impact.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Hematology
          Title: Hematology (Amsterdam, Netherlands)
          Publisher: Informa UK Limited
          ISSN (Electronic): 1607-8454
          ISSN (Print): 1024-5332
          Publication date (Electronic): Dec 2022
          Volume: 27
          Issue: 1
          Affiliations
          [1 ] Department of Hematology, Affiliated Changzhou Second Hospital of Nanjing Medical University, Changzhou, People's Republic of China.
          [2 ] Department of Hematology, Wuxi Third people's hospital, Wuxi, People's Republic of China.
          [3 ] National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Soochow University, Suzhou, People's Republic of China.
          [4 ] Suzhou jsuniwell medical laboratory, Suzhou, People's Republic of China.
          [5 ] Department of Hematology, The Third Affiliated Hospital of Soochow University, Changzhou, People's Republic of China.
          [6 ] Department of Hematology, Affiliated Jintan People's Hospital of Jiangsu University, Changzhou, People's Republic of China.
          [7 ] Department of Hematology, Wuxi Second people's hospital, Wuxi, People's Republic of China.
          Article
          DOI: 10.1080/16078454.2022.2103964
          PubMed ID: 36066283
          SO-VID: da3a876f-9368-41d5-83ae-a57ba03173d1
          History

          Keywords: CEBPA,Acute myeloid leukemia,mutation,WT1
          Data availability:
          Keywords: CEBPA, Acute myeloid leukemia, mutation, WT1

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