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      Coagulative, Fibrinolytic and Metabolic Pattern in Patients with Central Retinal Vein Occlusion

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          Central retinal vein occlusion (CRVO) is an important cause of visual loss. Many risk factors have been associated with CRVO onset at various ages. Among them diabetes mellitus, hypertension, immunologic disorders, increase in blood viscosity and coagulation, decrease of fibrinolysis have been reported in many subjects. The aim of our study was to detect the metabolic, coagulative and fibrinolytic pattern in 54 patients (26 men, 28 women, mean age 50.4 ± 12.3) affected by CRVO. We excluded from the study patients with other ocular disorders. A fibrinolytic impairment is the most common feature in our population. It occurs either in dysmetabolic or in nonmetabolic subjects. Such data suggest a prominent role of the fibrinolytic system in the pathogenesis of CRVO.

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          Activated protein C resistance and anticoagulant proteins in young adults with central retinal vein occlusion.

          Central retinal vein occlusion is a disease that is most common in old people, and often associated with atherosclerosis, hypertension, diabetes or glaucoma. Since these diseases are much less evident in young people, we wanted to investigate the prevalence of disorders in the most common anticoagulant proteins in a group of young patients with central retinal vein occlusion.
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            Protein C, protein S and antithrombin III deficiencies in retinal vein occlusion


              Author and article information

              S. Karger AG
              April 2002
              02 April 2002
              : 216
              : 2
              : 108-112
              aDepartment of Ophthalmology and Neurosurgery, and bInstitute of Medical Semeiotics, ‘Centro per lo Studio delle Malattie Dismetaboliche e della Aterosclerosi’, University of Siena, Italy
              48308 Ophthalmologica 2002;216:108–112
              © 2002 S. Karger AG, Basel

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              Page count
              Tables: 2, References: 28, Pages: 5
              Original Paper · Travail original · Originalarbeit


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