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      A Telementoring Program and Hepatitis C Virus Care in Rural Patients

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          Abstract

          Background: Rural patients with chronic hepatitis C virus (HCV) infection may be less likely to access HCV care than those in urban areas. A telementoring, task-shifting model has been implemented to address the unmet needs of HCV care. Evidence is needed on whether this intervention improves HCV care in rural HCV patients.

          Methods: We compared three key HCV care indicators among Medicare patients with chronic hepatitis C in 2014–2016 by urban–rural status between New Mexico with a telementoring program and Pennsylvania without such a program. We classified each patient's urban–rural status based on his or her ZIP code of residence. We used multivariable log-binomial regressions to examine the relative probability of receiving HCV care by urban and rural status in two states.

          Results: In New Mexico, 41.3% of HCV patients resided in rural areas ( N = 1155). In Pennsylvania, rural patients accounted for 13.2% ( N = 1775). The unadjusted overall rates of receiving HCV RNA or genotype testing within 12 months before HCV treatment were 76.1% in “rural-New Mexico” versus 73.3% in “rural-Pennsylvania,” 66.2% in “urban-New Mexico,” and 70.2% in “urban-Pennsylvania.” Post-treatment HCV RNA testing rate was also high in “rural-New Mexico” (83.0%). After adjusting for demographic and clinical characteristics, “rural-New Mexico” HCV patients who received HCV treatment still had the highest probability of taking HCV RNA or genotype testing before HCV treatment, compared with other groups (relative risk [95% confidence interval]: 0.91 [0.84–1.00] in “rural-Pennsylvania,” 0.85 [0.78–0.93] in “urban-New Mexico,” and 0.93 [0.87–1.00] in “urban-Pennsylvania”).

          Conclusions: The telementoring program may help improve HCV care in rural patients.

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          Most cited references17

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          Outcomes of treatment for hepatitis C virus infection by primary care providers.

          The Extension for Community Healthcare Outcomes (ECHO) model was developed to improve access to care for underserved populations with complex health problems such as hepatitis C virus (HCV) infection. With the use of video-conferencing technology, the ECHO program trains primary care providers to treat complex diseases. We conducted a prospective cohort study comparing treatment for HCV infection at the University of New Mexico (UNM) HCV clinic with treatment by primary care clinicians at 21 ECHO sites in rural areas and prisons in New Mexico. A total of 407 patients with chronic HCV infection who had received no previous treatment for the infection were enrolled. The primary end point was a sustained virologic response. A total of 57.5% of the patients treated at the UNM HCV clinic (84 of 146 patients) and 58.2% of those treated at ECHO sites (152 of 261 patients) had a sustained viral response (difference in rates between sites, 0.7 percentage points; 95% confidence interval, -9.2 to 10.7; P=0.89). Among patients with HCV genotype 1 infection, the rate of sustained viral response was 45.8% (38 of 83 patients) at the UNM HCV clinic and 49.7% (73 of 147 patients) at ECHO sites (P=0.57). Serious adverse events occurred in 13.7% of the patients at the UNM HCV clinic and in 6.9% of the patients at ECHO sites. The results of this study show that the ECHO model is an effective way to treat HCV infection in underserved communities. Implementation of this model would allow other states and nations to treat a greater number of patients infected with HCV than they are currently able to treat. (Funded by the Agency for Healthcare Research and Quality and others.).
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            The increasing burden of mortality from viral hepatitis in the United States between 1999 and 2007.

            The increasing health burden and mortality from hepatitis B virus (HBV) and hepatitis C virus (HCV) in the United States are underappreciated. To examine mortality from HBV; HCV; and, for comparison, HIV. Analysis of U.S. multiple-cause mortality data from 1999 to 2007 from the National Center for Health Statistics. All U.S. states and the District of Columbia. Approximately 22 million decedents. Age-adjusted mortality rates from HBV, HCV, and HIV. Logistic regression analyses of 2007 data generated 4 independent models per outcome (HCV- or HBV-related deaths) that each included 1 of 4 comorbid conditions and all sociodemographic characteristics. Between 1999 and 2007, recorded deaths from HCV [corrected] increased significantly to 15,106, whereas deaths from HIV declined to 12,734 by 2007. Factors associated with HCV-related deaths included chronic liver disease, HBV co-infection, alcohol-related conditions, minority status, and HIV co-infection. Factors that increased odds of HBV-related death included chronic liver disease, HCV co-infection, Asian or Pacific Islander descent, HIV co-infection, and alcohol-related conditions. Most deaths from HBV and HCV occurred in middle-aged persons. A person other than the primary physician of the decedent frequently completed the death certificate, and HCV and HBV often were not detected and thus not reported as causes of death. By 2007, HCV had superseded HIV as a cause of death in the United States, and deaths from HCV and HBV disproportionately occurred in middle-aged persons. To achieve decreases in mortality similar to those seen with HIV requires new policy initiatives to detect patients with chronic hepatitis and link them to care and treatment. Centers for Disease Control and Prevention.
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              The Impact of Project ECHO on Participant and Patient Outcomes: A Systematic Review.

              Project Extension for Community Healthcare Outcomes (ECHO) uses tele-education to bridge knowledge gaps between specialists at academic health centers and primary care providers from remote areas. It has been implemented to address multiple medical conditions. The authors examined evidence of the impact of all Project ECHO programs on participant and patient outcomes.
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                Author and article information

                Journal
                Telemed Rep
                Telemed Rep
                tmr
                Telemedicine Reports
                Mary Ann Liebert, Inc., publishers (140 Huguenot Street, 3rd FloorNew Rochelle, NY 10801USA )
                2692-4366
                May 2021
                2021
                13 May 2021
                : 2
                : 1
                : 143-147
                Affiliations
                [ 1 ]Department of Medicine, College of Medicine, The Pennsylvania State University, Hershey, Pennsylvania, USA.
                [ 2 ]Department of Public Health Sciences, College of Medicine, The Pennsylvania State University, Hershey, Pennsylvania, USA.
                [ 3 ]Department of Health Policy and Administration, College of Health and Human Development, The Pennsylvania State University, University Park, Pennsylvania, USA.
                Author notes
                [*]*Address correspondence to: Ping Du, MD, PhD, Department of Medicine and Department of Public Health Sciences, College of Medicine, The Pennsylvania State University, 90 Hope Drive, MC: A210, Hershey, PA 17033, USA, pd7561@ 123456gmail.com
                Author information
                https://orcid.org/0000-0003-1329-790X
                Article
                10.1089/tmr.2021.0001
                10.1089/tmr.2021.0001
                8142682
                de9dfd8f-389a-43ef-b877-8fa5602b6745
                © Ping Du et al., 2021; Published by Mary Ann Liebert, Inc.

                This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] ( http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : Accepted March 12, 2021
                Page count
                Tables: 3, References: 20, Pages: 5
                Categories
                Brief Communication

                hcv care,hepatitis c virus (hcv),telementoring
                hcv care, hepatitis c virus (hcv), telementoring

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