Effects of  D -Glyceraldehyde and 3- o -Methylglucose upon Fluorescence of Reduced Pyridine Nucleotides from Perifused Isolated Pancreatic Islets

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Abstract

In perifused pancreatic islets, the fluorescence of reduced pyridine nucleotides was recorded continuously. D-Glyceraldehyde (5 mM) or 3- o-methylglucose (27.5 m M) never caused a net fluorescence increase. Since stepwise changes of the D-glucose concentration between 0 and 20 m M always induced a fluorescence increase, it is concluded that glucose on the one hand and glyceraldehyde or 3- o-methylglucose on the other hand cause different metabolic states in pancreatic islets.

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Journal ID (publisher-id): HRE

Journal ID (nlm-ta): Horm Res Paediatr

Journal ID (doi): 10.1159/issn.1663-2818

Title: Hormone Research in Paediatrics

Publisher: S. Karger AG

ISSN (Print): 1663-2818

ISSN (Electronic): 1663-2826

Publication date Subscription-year: 1976

Publication date (Print): 1976

Publication date (Electronic): 25 November 2008

Volume: 7

Issue: 3

Pages: 164-171

Affiliations

Pharmakologisches Institut der Universität Göttingen, Göttingen

Article

Publisher ID: 178725 Other ID: Horm Res 1976;7:164–171

DOI: 10.1159/000178725

PubMed ID: 12074

SO-VID: df970dee-0a63-41a2-aaa0-f0caae1827c7

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Effects of D-Glyceraldehyde and 3- o-Methylglucose upon Fluorescence of Reduced Pyridine Nucleotides from Perifused Isolated Pancreatic Islets

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Karger: Endocrinology

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