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      Acute esophageal obstruction caused by reverse migration of gastric bezoars: A case report

      case-report

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          Abstract

          BACKGROUND

          Bezoars can be found anywhere in the gastrointestinal tract. Esophageal bezoars are rare. Esophageal bezoars are classified as either primary or secondary. It is rarely reported that secondary esophageal bezoars caused by reverse migration from the stomach lead to acute esophageal obstruction. Guidelines recommend urgent upper endoscopy (within 24 h) for these impactions without complete esophageal obstruction and emergency endoscopy (within 6 h) for those with complete esophageal obstruction. Gastroscopy is regarded as the mainstay for the diagnosis and treatment of esophageal bezoars.

          CASE SUMMARY

          A 59-year-old man was hospitalized due to nausea, vomiting and diarrhea for 2 d and sudden retrosternal pain and dysphagia for 10 h. He had a history of type 2 diabetes mellitus for 9 years. Computed tomography revealed dilated lower esophagus, thickening of the esophageal wall, a mass-like lesion with a flocculent high-density shadow and gas bubbles in the esophageal lumen. On gastroscopy, immovable brown bezoars were found in the lower esophagus, which led to esophageal obstruction. Endoscopic fragmentation was successful, and there were no complications. The symptoms of retrosternal pain and dysphagia disappeared after treatment. Mucosal superficial ulcers were observed in the lower esophagus. Multiple biopsy specimens from the lower esophagus revealed nonspecific findings. The patient remained asymptomatic, and follow-up gastroscopy 1 wk after endoscopic fragmentation showed no evidence of bezoars in the esophagus or the stomach.

          CONCLUSION

          Acute esophageal obstruction caused by bezoars reversed migration from the stomach is rare. Endoscopic fragmentation is safe, effective and minimally invasive and should be considered as the first-line therapeutic modality.

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          Most cited references15

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          Gastrointestinal bezoars: sonographic and CT characteristics.

          The purpose of this study was to assess the value of imaging studies--conventional abdominal radiographs, sonography, and CT--in the diagnosis of gastrointestinal bezoars. A review was made of the radiologic findings of 17 consecutive patients with surgically verified gastrointestinal bezoars over a period of 51 months. Twelve patients had a history of previous gastric surgery. In no patient was a bezoar clinically suspected. Phytobezoars were recorded in 16 patients and a trichobezoar in only one. A total of 33 bezoars were identified at surgery. Two patients had isolated gastric bezoars, whereas 15 patients had bezoars located in the small bowel. Among the latter group, associated gastric bezoars were found in eight patients, and five patients had multiple intestinal bezoars. Abdominal radiographs revealed bezoars in three patients, sonography revealed bezoars in 15, and CT revealed bezoars in all 17. Seven patients had associated gastric bezoars revealed at CT versus only two patients with gastric bezoars revealed at sonography. CT revealed multiple intestinal bezoars in five patients whereas sonography revealed them in only two patients. Both sonography and CT are reliable methods for diagnosing gastrointestinal bezoars. CT is more accurate, however, and exhibits a quite characteristic bezoar image; in addition, this imaging technique is able to reveal the presence of additional gastrointestinal bezoars.
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            Gastric phytobezoars may be treated by nasogastric Coca-Cola lavage.

            Large gastric phytobezoars may occur in patients with gastric dysmotility disorders. Treatment options include dissolution with enzymes, endoscopic fragmentation with removal or aspiration, and surgery. We report our experience with nasogastric cola lavage therapy. Over an 8-year period, five consecutive patients were referred to our unit for endoscopic treatment of large gastric phytobezoars. They included one patient with lobectomy for lung cancer and four patients with diabetic gastroparesis. An initial attempt of endoscopic fragmentation and removal was unsuccessful. Patients were treated with 3 l of Coca-Cola nasogastric lavage over 12 h. Nasogastric lavage was very well tolerated by the patients. Complete phytobezoar dissolution was achieved in one session in all cases. There were no procedure-related complications. The dissolution of large gastric phytobezoars with cola nasogastric lavage is a safe, rapid and effective method. Patients may be treated in the medical ward, avoiding therapeutic endoscopy or surgery.
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              How good is cola for dissolution of gastric phytobezoars?

              To evaluate the efficacy of cola treatment for gastric phytobezoars, including diospyrobezoars. A total of 17 patients (range: 48 to 78 years) with symptomatic gastric phytobezoars treated with cola and adjuvant endoscopic therapy were reviewed. Three liters of cola lavage (10 cases) or drink (7 cases) were initially used, and then endoscopic fragmentation was done for the remnant bezoars by using a lithotripsy basket or a polypectomy snare. The overall success of dissolving a gastric phytobezoars with using three liters of cola and the clinical and endoscopic findings were compared retrospectively between four cases of complete dissolution by using only cola and 13 cases of partial dissolution with cola. After 3 L of cola lavage or drinking, a complete dissolution of bezoars was achieved in four patients (23.5%), while 13 cases (76.5%) were only partially dissolved. Phytobezoars (4 of 6 cases) were observed more frequently than diospyrobezoars (0 of 11) in the group that underwent complete dissolution (P = 0.006). Gender, symptom duration, size of bezoar and method of cola administration were not significantly different between the two groups. Twelve of 13 patients with residual bezoars were completely treated with a combination of cola and endoscopic fragmentation. The rate of complete dissolution with three liters of cola was 23.5%, but no case of diospyrobezoar was completely dissolved using this method. However, pretreatment with cola may be helpful and facilitate endoscopic fragmentation of gastric phytobezoars.
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                Author and article information

                Contributors
                Journal
                World J Clin Cases
                WJCC
                World Journal of Clinical Cases
                Baishideng Publishing Group Inc
                2307-8960
                26 July 2020
                26 July 2020
                : 8
                : 14
                : 3130-3135
                Affiliations
                Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
                Key Laboratory for Gastrointestinal Diseases, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
                Department of Gastroenterology, Affiliated Hospital of Northwest Minzu University, Lanzhou 730000, Gansu Province, China
                Department of Gastroenterology, Affiliated Hospital of Northwest Minzu University, Lanzhou 730000, Gansu Province, China
                Department of Gastroenterology, Affiliated Hospital of Northwest Minzu University, Lanzhou 730000, Gansu Province, China
                Department of Gastroenterology, Affiliated Hospital of Northwest Minzu University, Lanzhou 730000, Gansu Province, China
                Department of Gastroenterology, Affiliated Hospital of Northwest Minzu University, Lanzhou 730000, Gansu Province, China
                Department of Radiology, Affiliated Hospital of Northwest Minzu University, Lanzhou 730000, Gansu Province, China
                Department of Gastroenterology, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
                Key Laboratory for Gastrointestinal Diseases, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China. zhouyn@ 123456lzu.edu.cn
                Author notes

                Author contributions: Zhang FH and Ding XP were attending physicians for the patient, reviewed the literature and contributed to manuscript drafting; Zhou YN and Zhang JH reviewed the literature and contributed to manuscript drafting; Miao LS and Bai LY performed the upper gastrointestinal endoscopy and endoscopic therapy, and contributed to manuscript drafting; Ge HL was responsible for imaging diagnosis and reviewed the literature; Zhou YN was responsible for revision of the manuscript for important intellectual content; all authors issued final approval for the version to be submitted.

                Corresponding author: Yong-Ning Zhou, MD, PhD, Professor, Department of Gastroenterology, Key Laboratory for Gastrointestinal Diseases, the First Hospital of Lanzhou University, No. 1, West Donggang Road, Lanzhou 730000, Gansu Province, China. zhouyn@ 123456lzu.edu.cn

                Article
                jWJCC.v8.i14.pg3130
                10.12998/wjcc.v8.i14.3130
                7385598
                e1848d47-17a8-45ba-9a4a-bb100083c95f
                ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.

                This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

                History
                : 28 March 2020
                : 4 May 2020
                : 4 July 2020
                Categories
                Case Report

                esophageal bezoars,esophageal obstruction,acute,endoscopic fragmentation,case report

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