Diuresis-Related Weight Loss Reflects Interstitial Compartment Decongestion with Minimal Impact on Intravascular Volume Expansion or Outcomes in Post-Acute Heart Failure
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Abstract
Findings from heart failure (HF) studies linking diuresis-related weight loss to clinical
decongestion and outcomes are mixed. Differential responses of interstitial and intravascular
volume compartments to diuretic therapy and heterogeneity in volume profiles may confound
the clinical interpretation of weight loss in patients with HF.