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      Adult Height in Turner Syndrome: Results of a Multinational Survey 1993

      ,

      Hormone Research in Paediatrics

      S. Karger AG

      Adult height, Turner syndrome

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          Abstract

          Under the auspices of ESPE/LWPES, a survey on spontaneous adult height in patients with Turner syndrome was conducted in 12 European countries. A total of 661 patients (45, X = 51%) with a median age of 23.6 years (range: 16-63) who had never received any growth-promoting treatment until the age of 14 had reached a mean height of 144.3 ± 6.7 cm. There was no height difference between those (n = 220) who had received oxandrolone and/or estrogen after the age of 14 years and those (n = 441) who never received any treatment until the age of 20. On average, there was no major gain in height after an age of 16 years. The height achieved was positively associated with the height of normal women in the underlying population. There was a high positive correlation (r = 0.436; p < 0.0001) between adult height and target height in adults never treated. A positive correlation of these parameters was present irrespective of karyotype (45, X vs. ‘others’) or treatment with oxandrolone/estrogen. The findings strengthen the observations on height development from national studies.

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          Author and article information

          Journal
          HRE
          Horm Res Paediatr
          10.1159/issn.1663-2818
          Hormone Research in Paediatrics
          S. Karger AG
          1663-2818
          1663-2826
          1994
          1994
          05 December 2008
          : 42
          : 3
          : 90-94
          Affiliations
          Growth Research Center, University Children’s Hospital, Tübingen, FRG
          Article
          184154 Horm Res 1994;42:90–94
          10.1159/000184154
          7995618
          © 1994 S. Karger AG, Basel

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          Page count
          Pages: 5
          Categories
          Original Paper

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