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      Influenza A-induced cardiogenic shock requiring temporary ECMO support and urgent heart transplantation.

      The Thoracic and cardiovascular surgeon
      Adolescent, Anticoagulants, adverse effects, Cardiomyopathy, Dilated, complications, surgery, Extracorporeal Membrane Oxygenation, Female, Heart Transplantation, Heparin, Humans, Influenza A virus, pathogenicity, Influenza, Human, virology, Shock, Cardiogenic, etiology, Thrombocytopenia, chemically induced, Time Factors, Treatment Outcome

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          Abstract

          We report a case of a child with familial cardiomyopathy who contracted H1N1 influenza followed by cardiovascular collapse requiring immediate arteriovenous ECMO support. Despite the lack of experience with heart transplantation (HTx) soon after H1N1 infection, HTx was considered as an exit strategy since restoration of cardiac function was considered unlikely. In contrast to the most common indication for ECMO use in patients with H1N1 infection, early ECMO support in cases with infection-induced myocardial decompensation may be lifesaving. Additionally, this report shows that urgent heart transplantation in a patient on ECMO support can be performed safely after recent H1N1 infection and simultaneous heparin-induced thrombocytopenia, which has not been reported before. This case also indicates that H1N1 vaccination should be considered for potential transplantation candidates to prevent severe infection. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

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