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      The Impact of Integrated Evaluation of Hemodynamics on Management of Preterm Infants with Late-Onset Compromised Systemic Circulation

      1 , 1 , 1 , 1

      American Journal of Perinatology

      Georg Thieme Verlag KG

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          Abstract

          Objectives To study the impact of integrated evaluation of hemodynamics (IEH), using targeted neonatal echocardiography (TNE), cerebral regional tissue oxygenation (crRTO), and fractional oxygen extraction (FOE), using near-infrared spectroscopy (NIRS) on the management of infants with late-onset compromised systemic circulation (LCSC), and evaluation of the hemodynamic characteristics.

          Study Design Retrospective cohort study comparing infants with LCSC who underwent IEH (April 2014 to May 2016) with an earlier EPOCH who did not undergo IEH (January 2012 to March 2014). The primary outcome was the time to recovery.

          Results Total 43 infants were included; 18 infants underwent IEH with a median (IQR) 2 (1–3) assessments per infant. The time to recovery was shorter in IEH group with a median (IQR) 28 hours (15–62) compared with non-IEH group 96 hours (30–160). Autoregulation was compromised in 50%, and systemic vascular resistance (SVR) was low in 67%.

          Conclusion IEH was associated with shorter time to recovery in infants with LCSC.

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          Author and article information

          Journal
          American Journal of Perinatology
          Amer J Perinatol
          Georg Thieme Verlag KG
          0735-1631
          1098-8785
          July 27 2017
          August 2017
          April 06 2017
          August 2017
          : 34
          : 10
          : 1011-1019
          Affiliations
          [1 ]Section of Neonatology, Department of Paediatrics, University of Manitoba, Winnipeg, Manitoba, Canada
          Article
          10.1055/s-0037-1601439
          © 2017

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