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      Fiebre aftosa en seres humanos: Un caso en Chile Translated title: Foot and mouth disease in human beings: A human case in Chile

      case-report
      Revista chilena de infectología
      Sociedad Chilena de Infectología
      Fiebre aftosa, Chile, foot and mouth disease, Chile

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          Abstract

          La fiebre aftosa se presenta en los biungulados, siendo el cerdo el animal más susceptible. La infección de estos animales lleva a cuantiosas pérdidas económicas por disminución de la producción de leche o carne. En la actualidad esta enfermedad constituye una plaga que causa serios trastornos en el comercio pecuario mundial y se la considera como una enfermedad trans-fronteriza. Chile está libre se esta enfermedad desde 1987. La fiebre aftosa en seres humanos ha sido descrita principalmente en Europa, habiéndose confirmado, aproximadamente, unos 40 casos por aislamiento viral y detección de anticuerpos específicos. Se describen los principales casos de fiebre aftosa en seres humanos descritos en la literatura científica, incluyendo un caso ocurrido en Chile en 1961. Se discute la importancia de esta enfermedad en seres humanos y se cuestiona el planteamiento de que es una zoonosis

          Translated abstract

          Foot and mouth disease (FMD) of cattle can cause a significant economic burden and is thus for one of the most feared of cattle disease. FMD is endemic in South America, Africa, Asia and parts of Europe and it is characterized by vesicles in different locations, mainly mouth, feet and teats leading to severe animal weakness. Currently most countries refuse to import livestock and livestock products from FMD areas. North and Central America are currently free of FMD and Chile is free of FMD from 1987. Approximately 40 cases of human infection with FMD virus have been reported, mostly in Europe, and confirmed by virus isolation and the detection of a specific immune response. We discuss the case of a human infection with FMD virus occurred in Chile in 1961 and other relevant cases reported. FMD does not currently present a threat to public health. Even though the FMD virus has the potential to mutate rapidly and emerge as a significant human zoonosis; the rarity of the disease in humans despite a long history of close contact with FMD infected animals suggests that the risk is highly improbable. Then FMD should not be managed as a zoonosis

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          Most cited references29

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          Inhalation, persistence and dispersal of foot-and-mouth disease virus by man

          SUMMARY Sampling of human subjects, who had been in contact with animals infected with foot-and-mouth disease (FMD) virus, showed that virus could be recovered from the nose, throat, saliva and from air expelled during coughing, sneezing, talking and breathing. The amounts of virus recovered paralleled those collected with a large-volume sampler and multistage impinger and these findings confirmed that the highest recovery of airborne virus was from infected pigs followed by cattle and sheep. More virus was found in the noses of those examining infected animals than in those operating the samplers, but there was variation between the subjects. In the majority there was a 1·8 log fall in titre by 3·5 hr., but virus persisted in the nose of one subject for 28 hr. Nose blowing or washing the nostrils did not remove virus completely, nor were cloth or industrial masks completely effective in preventing inhalation of virus. It was possible to transmit virus from infected subjects to others on one occasion. No clinical cases of FMD in man resulted from exposure, nor was there any rise in antibody. Use was made of these findings in determining sites of aerosol excretion in animals, and the results are discussed in relation to FMD in man and to the spread of respiratory viruses by the airborne route.
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            Ihalation, persistence and dispersal f foot-and-mouth disease virus by man.

            Sampling of human subjects, who had been in contact with animals infected with foot-and-mouth disease (FMD) virus, showed that virus could be recovered from the nose, throat, saliva and from air expelled during coughing, sneezing, talking and breathing. The amounts of virus recovered paralleled those collected with a large-volume sampler and multistage impinger and these findings confirmed that the highest recovery of airborne virus was from infected pigs followed by cattle and sheep. More virus was found in the noses of those examining infected animals than in those operating the samplers, but there was variation between the subjects. In the majority there was a 1.8 log fall in titre by 3.5 hr., but virus persisted in the nose of one subject for 28 hr. Nose blowing or washing the nostrils did not remove virus completely, nor were cloth or industrial masks completely effective in preventing inhalation of virus. It was possible to transmit virus from infected subjects to others on one occasion. No clinical cases of FMD in man resulted from exposure, nor was there any rise in antibody. Use was made of these findings in determining sites of aerosol excretion in animals, and the results are discussed in relation to FMD in man and to the spread of respiratory viruses by the airborne route.
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              FIEBRE AFTOSA

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                Author and article information

                Journal
                rci
                Revista chilena de infectología
                Rev. chil. infectol.
                Sociedad Chilena de Infectología (Santiago, , Chile )
                0716-1018
                April 2007
                : 24
                : 2
                : 160-163
                Affiliations
                [01] Santiago orgnameUniversidad Andrés Bello orgdiv1Facultad de Ecología y Recursos Naturales orgdiv2Escuela de Medicina Veterinaria Chile
                Article
                S0716-10182007000200013 S0716-1018(07)02400213
                10.4067/S0716-10182007000200013
                e8f88f63-36f6-4d96-b61d-b25343c06ed4

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 07 November 2005
                : 27 September 2006
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 24, Pages: 4
                Product

                SciELO Chile

                Categories
                CRÓNICA

                Chile,foot and mouth disease,Fiebre aftosa
                Chile, foot and mouth disease, Fiebre aftosa

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