12
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Leading a Digital Transformation in the Pharmaceutical Industry: Reimagining the Way We Work in Global Drug Development

      review-article
      1 , , 1
      Clinical Pharmacology and Therapeutics
      John Wiley and Sons Inc.

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          We are experiencing seminal times in computing that seem to define a fourth industrial revolution. This may fundamentally change the way we live, work, and relate to one another. Embracing data and digital information is a top priority for most industries these days, and Life Sciences is no exception. The pharmaceutical industry in particular is fundamentally a data‐driven business. Inspired by a desire to “Go Big on Data,” we developed a strategic roadmap defining a digital transformation to reimagine the way we work in Novartis Global Drug Development, leveraging data science to generate and inject actionable insights into our best practices. We launched a program called Nerve Live, and built a state‐of‐the‐art data and analytics platform to harness past and present operational data, providing access to decades of drug development “experience” buried across multiple sources. The platform enabled the systematic application of machine learning and predictive analytics to generate “intelligence”: new insights across multiple functional areas. To action the insights and create “value,” we crafted skillfully designed end‐user applications for domain experts to plan, track, predict, compare and monitor domain activities, optimize costs, and maximize quality. Today, the Nerve Live program enables insights‐driven decision making at scale, unlocking productivity, and providing transparency across the Novartis Global Drug Development organization and beyond. We identified three main drivers making the Nerve Live program successful and enabling the associated digital transformation to flourish. We discuss the challenges, highlight the benefits, and see the importance of leading the way to become future proof.

          Related collections

          Most cited references8

          • Record: found
          • Abstract: not found
          • Article: not found

          Empirical studies of agile software development: A systematic review

            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            The Fourth Industrial Revolution: What It Means and How to Respond

              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              The health care innovation bubble

                Bookmark

                Author and article information

                Contributors
                luca.finelli@novartis.com
                Journal
                Clin Pharmacol Ther
                Clin Pharmacol Ther
                10.1002/(ISSN)1532-6535
                CPT
                Clinical Pharmacology and Therapeutics
                John Wiley and Sons Inc. (Hoboken )
                0009-9236
                1532-6535
                30 May 2020
                October 2020
                30 May 2020
                : 108
                : 4 ( doiID: 10.1002/cpt.v108.4 )
                : 756-761
                Affiliations
                [ 1 ] Novartis International AG Basel Switzerland
                Author notes
                [*] [* ] Correspondence: Luca A. Finelli ( luca.finelli@ 123456novartis.com )

                Article
                CPT1850
                10.1002/cpt.1850
                7540662
                32294230
                e96b40b2-c558-45c9-82f1-2997fb5c3485
                © 2020 The Authors. Clinical Pharmacology & Therapeutics published by Wiley Periodicals LLC on behalf of American Society for Clinical Pharmacology and Therapeutics.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

                History
                : 19 December 2019
                : 29 March 2020
                Page count
                Figures: 2, Tables: 1, Pages: 6, Words: 4167
                Categories
                Mini‐Review
                Reviews
                Mini‐Review
                Custom metadata
                2.0
                October 2020
                Converter:WILEY_ML3GV2_TO_JATSPMC version:5.9.2 mode:remove_FC converted:07.10.2020

                Pharmacology & Pharmaceutical medicine
                Pharmacology & Pharmaceutical medicine

                Comments

                Comment on this article