Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
18
March
2016
Publication date Collection: 2016
Volume: 11
Issue: 3
Electronic Location Identifier: e0151850
Affiliations
[1
]Department of Microbiology, Immunology and Biochemistry, College of Medicine, University
of Tennessee Health Sciences Center, Memphis, Tennessee, United States of America
[2
]Immuno Technologies Inc., Memphis, Tennessee, United States of America
[3
]Molecular Resource Center, University of Tennessee Health Sciences Center, Memphis,
Tennessee, United States of America
University of Kentucky College of Medicine, UNITED STATES
Author notes
Competing Interests: The authors have the following interests: Luciana Richer and Maria Gomes-Solecki are
employed by Immuno Technologies, Inc. MGS holds more than 5% financial interest in
Immuno Technologies, Inc. and in US Biologic, Inc. LR holds 5% financial interest
in Immuno Technologies, Inc. MGS advises US Biologic on development of reservoir targeted
vaccines for Lyme borreliosis. MGS holds several relevant patents (Recombinant constructs
of Borrelia burgdorferi, US 7,605,248; Groups of Borrelia burgdorferi and Borrelia
afzelii that cause Lyme Disease in humans, US 7,582,304; Oral vaccine for Borrelia,
US 2009/0297560 A1). This did not alter the authors' adherence to PLOS ONE policies
on sharing data and materials.
Conceived and designed the experiments: RM LR MGS. Performed the experiments: RM DLJ
LR. Analyzed the data: RM DLJ MGS. Wrote the paper: MGS.
Article
Publisher ID:
PONE-D-15-47195
DOI: 10.1371/journal.pone.0151850
PMC ID: 4798528
PubMed ID: 26990760
SO-VID: ec135f75-844a-4e48-a2f7-e110d42efe2b
Copyright © © 2016 Melo et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
The authors thank the National Institutes of Health, National Institute of Allergy
and Infectious Diseases for funding support (R44 AI096551) to MGS via Immuno Technologies,
Inc. Immuno Technologies, Inc. provided support in the form of salaries for authors
[LR, MGS], but did not have any additional role in the study design, data collection
and analysis, decision to publish, or preparation of the manuscript. The specific
roles of these authors are articulated in the Author Contributions section.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Bacteria
Subject:
Borrelia
Subject:
Borrelia Burgdorferi
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Borrelia
Subject:
Borrelia Burgdorferi
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Borrelia
Subject:
Borrelia Burgdorferi
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Antibodies
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Antibodies
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Antibodies
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Antibodies
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Immune System Proteins
Subject:
Antibodies
Subject:
Biology and Life Sciences
Subject:
Developmental Biology
Subject:
Metamorphosis
Subject:
Nymphs
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Vaccination and Immunization
Subject:
Vaccines
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Vaccination and Immunization
Subject:
Vaccines
Subject:
Medicine and Health Sciences
Subject:
Public and Occupational Health
Subject:
Preventive Medicine
Subject:
Vaccination and Immunization
Subject:
Vaccines
Subject:
Research and Analysis Methods
Subject:
Immunologic Techniques
Subject:
Immunoassays
Subject:
Enzyme-Linked Immunoassays
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Bacteria
Subject:
Spirochetes
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Spirochetes
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Spirochetes
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Response
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Response
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Heart
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Cardiovascular Anatomy
Subject:
Heart