New insights into calcifying pseudoneoplasm of the neuraxis (CAPNON): a 20-year radiological-pathological study of 37 cases.

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Abstract

Calcifying pseudoneoplasm of the neuraxis (CAPNON) is a rare entity that can occur anywhere within the central nervous system. Histologically, CAPNON has been characterised as a benign, calcified, fibro-osseous lesion with a characteristic chondromyxoid fibrillary matrix with dense calcification and varying degrees of spindle, epithelioid, fibrous, meningothelial and giant cells. The underlying aetiology of CAPNON is controversial and incompletely understood. The aim of this study was to perform a comprehensive radiological and histological review to further characterise this entity.

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Journal

Journal ID (iso-abbrev): Histopathology

Title: Histopathology

Publisher: Wiley

ISSN (Electronic): 1365-2559

ISSN (Print): 0309-0167

Publication date (Electronic): June 2020

Volume: 76

Issue: 7

Affiliations

[1 ] Department of Radiology, Nationwide Children's Hospital, Columbus, OH, USA.

[2 ] Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

Article

DOI: 10.1111/his.14066

PubMed ID: 31955449

SO-VID: f49f5fbd-f839-4fd7-b2fe-8f908cebc23c

History

Keywords: CAPNON,calcifying pseudoneoplasm,CRUDoma

Data availability:

Keywords: CAPNON, calcifying pseudoneoplasm, CRUDoma

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