Use of Polygenic Risk Scores to Select Screening Intervals After Negative Findings From Colonoscopy.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Polygenic risk scores (PRSs) could help to define starting ages for colorectal cancer (CRC) screening. However, the role of PRS in determining the length of screening interval after negative findings from colonoscopies is unclear. We aimed to evaluate CRC risk according to PRS and time since last negative colonoscopy.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): Clin Gastroenterol Hepatol

Title: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Publisher: Elsevier BV

ISSN (Electronic): 1542-7714

ISSN (Print): 1542-3565

Publication date (Electronic): Nov 2020

Volume: 18

Issue: 12

Affiliations

[1 ] Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg; Medical Faculty Heidelberg, University of Heidelberg, Heidelberg.

[2 ] Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg.

[3 ] Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg.

[4 ] Department for General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg.

[5 ] Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Genetic Tumour Epidemiology Group, University Medical Center Hamburg-Eppendorf, University Cancer Center Hamburg, Hamburg.

[6 ] Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany. Electronic address: h.brenner@dkfz-heidelberg.de.

Article

Publisher Item ID: S1542-3565(20)30622-4

DOI: 10.1016/j.cgh.2020.04.077

PubMed ID: 32376506

SO-VID: f6e02d62-a80f-46da-9b65-e2abd4686bf6

History

Keywords: Colorectal Cancer,Endoscopy,SNP,Genetic Variant

Data availability:

Keywords: Colorectal Cancer, Endoscopy, SNP, Genetic Variant

Comments

Comment on this article

scite_

Cited by 11

See all cited by