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      Clinical effectiveness and cost-effectiveness of cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment-resistant depression in primary care: the CoBalT randomised controlled trial

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          Abstract

          Only one-third of patients with depression respond fully to treatment with antidepressant medication. However, there is little robust evidence to guide the management of those whose symptoms are 'treatment resistant'.

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          Author and article information

          Journal
          Health Technology Assessment
          National Institute for Health and Care Research
          1366-5278
          2046-4924
          May 2014
          May 2014
          : 18
          : 31
          Affiliations
          [1 ]Centre for Academic Mental Health, School of Social and Community Medicine, University of Bristol, Bristol, UK
          [2 ]Mood Disorders Centre, University of Exeter, Exeter, UK
          [3 ]Centre for Academic Primary Care, School of Social and Community Medicine, University of Bristol, Bristol, UK
          [4 ]Academic Unit of Mental Health and Wellbeing, Institute of Health and Wellbeing, University of Glasgow, Glasgow, UK
          [5 ]ConDuCT Hub for Trials Methodology Research, School of Social and Community Medicine, University of Bristol, Bristol, UK
          [6 ]Primary Care Research Group, University of Exeter Medical School, Exeter, UK
          [7 ]Nottingham Psychotherapy Unit, Nottinghamshire Healthcare NHS Trust, Nottingham, UK
          [8 ]Avon and Wiltshire Mental Health Partnership NHS Trust, Chippenham, UK
          [9 ]Institute of Health and Wellbeing, General Practice and Primary Care Group, University of Glasgow, Glasgow, UK
          [10 ]School of Clinical Sciences, University of Bristol, Bristol, UK
          [11 ]Division of Psychiatry, University College London, London, UK
          Article
          10.3310/hta18310
          24824481
          f795b27c-a2dd-4370-99a5-78a9b9249696
          © 2014

          Free to read

          http://www.nationalarchives.gov.uk/doc/non-commercial-government-licence/non-commercial-government-licence.htm

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