Pablo M. De Salazar:
ORCID: https://orcid.org/0000-0002-8096-2001
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
InvestigationRole: MethodologyRole: SoftwareRole: ValidationRole: VisualizationRole:
Writing – original draft
Fred Lu:
ORCID: https://orcid.org/0000-0003-1026-5734
Role: ConceptualizationRole: Formal analysisRole: MethodologyRole: SoftwareRole: Writing
– original draft
James A Hay:
ORCID: https://orcid.org/0000-0002-1998-1844
Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: Writing – original
draft
Diana Gómez-Barroso:
ORCID: https://orcid.org/0000-0001-7388-1767
Role: Data curationRole: InvestigationRole: ResourcesRole: Writing – review & editing
Pablo Fernández-Navarro:
ORCID: https://orcid.org/0000-0001-9427-2581
Role: Data curationRole: InvestigationRole: ResourcesRole: VisualizationRole: Writing
– review & editing
Elena V Martínez:
ORCID: https://orcid.org/0000-0003-1620-7113
Role: Data curationRole: Writing – review & editing
Jenaro Astray-Mochales:
ORCID: https://orcid.org/0000-0001-6516-7176
Role: Data curationRole: InvestigationRole: ResourcesRole: Writing – review & editing
Rocío Amillategui:
ORCID: https://orcid.org/0000-0002-4481-1302
Role: Data curationRole: InvestigationRole: ResourcesRole: Writing – review & editing
Ana García-Fulgueiras:
ORCID: https://orcid.org/0000-0001-5931-3966
Role: Data curationRole: InvestigationRole: ResourcesRole: Writing – review & editing
Maria D Chirlaque: Role: Data curationRole: InvestigationRole: ResourcesRole: Writing – review & editing
Alonso Sánchez-Migallón:
ORCID: https://orcid.org/0000-0001-5662-6772
Role: Data curationRole: InvestigationRole: ResourcesRole: Writing – review & editing
Amparo Larrauri:
ORCID: https://orcid.org/0000-0002-1704-2245
Role: ConceptualizationRole: InvestigationRole: ResourcesRole: Writing – review &
editing
María J Sierra:
ORCID: https://orcid.org/0000-0003-0082-1397
Role: ConceptualizationRole: ResourcesRole: Writing – review & editing
Marc Lipsitch:
ORCID: https://orcid.org/0000-0003-1504-9213
Role: ConceptualizationRole: Formal analysisRole: MethodologyRole: SupervisionRole:
Writing – original draftRole: Writing – review & editing
Fernando Simón:
ORCID: https://orcid.org/0000-0002-3052-3430
Role: ConceptualizationRole: InvestigationRole: SupervisionRole: Writing – review
& editing
Mauricio Santillana:
ORCID: https://orcid.org/0000-0002-4206-418X
Role: Formal analysisRole: SupervisionRole: Writing – original draft
Miguel A Hernán: Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
ResourcesRole: SupervisionRole: Writing – original draft
Benjamin Althouse: Role: Editor
Journal ID (nlm-ta): PLoS Comput Biol
Journal ID (iso-abbrev): PLoS Comput Biol
Journal ID (publisher-id): plos
Title:
PLoS Computational Biology
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-734X
ISSN
(Electronic):
1553-7358
Publication date
(Electronic):
31
March
2022
Publication date Collection:
March
2022
Volume: 18
Issue: 3
Electronic Location Identifier: e1009964
Affiliations
[1
]
Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard TH Chan
School of Public Health, Boston, Massachusetts, United States of america
[2
]
Machine Intelligence Lab, Boston Children’s Hospital, Boston, Massachusetts, United
States
[3
]
Computational Health Informatics Program, Boston Children’s Hospital, Boston, Massachusetts,
United States of america
[4
]
Centro Nacional de Epidemiología, Carlos III Health Institute, Madrid, Spain
[5
]
Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP),
Madrid, Spain
[6
]
Centro de Coordinación de Alertas y Emergencias Sanitarias, Ministry of Health, Madrid,
Spain
[7
]
Directorate-General for Public Health, Madrid General Health Authority, Madrid, Spain
[8
]
Department of Epidemiology, Regional Health Council, IMIB-Arrixaca, Murcia, Spain
CIBER in Epidemiology and Public Health (CIBERESP), Madrid, Spain
[9
]
Consorcio de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINF),
Madrid, Spain
[10
]
Department of Pediatrics, Harvard Medical School, Harvard University, Boston, Massachusetts,
United States of america
[11
]
CAUSALab, Department of Epidemiology and Department of Biostatistics, Harvard T.H.
Chan School of Public Health, Boston, Massachusetts, United States of america
University of Washington, UNITED STATES
Author notes
I have read the journal’s policy and some of the co-authors of this manuscript have
the following competing interests: ML discloses honoraria/consulting from Merck, Affinivax,
Sanofi-Pasteur, Bristol Myers-Squibb, and Antigen Discovery; research funding (institutional)
from Pfizer, and an unpaid scientific advice to Janssen, Astra-Zeneca, One Day Sooner,
and Covaxx (United Biomedical). MS discloses having received institutional research
support from Johnson and Johnson.The rest of co-authors declare no competing interest.
‡ These authors are joint senior authors on this work.
Author information
Article
Publisher ID:
PCOMPBIOL-D-20-02097
DOI: 10.1371/journal.pcbi.1009964
PMC ID: 9004750
PubMed ID: 35358171
SO-VID: fa3223b8-26ec-4857-a3cc-a3e27c8fcc5a
Copyright © © 2022 De Salazar et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by:
funder-id http://dx.doi.org/10.13039/100008054, Fundación Ramón Areces;
Award Recipient
:
ORCID: https://orcid.org/0000-0002-8096-2001
Pablo M. De Salazar
Funded by:
funder-id http://dx.doi.org/10.13039/100000057, National Institute of General Medical Sciences;
Award ID: U54GM088558
Award Recipient
:
ORCID: https://orcid.org/0000-0002-1998-1844
James A Hay
Funded by:
funder-id http://dx.doi.org/10.13039/100000052, NIH Office of the Director;
Award ID: DP5-OD028145
Award Recipient
:
ORCID: https://orcid.org/0000-0002-1998-1844
James A Hay
Funded by:
Morris-Singer
Award Recipient
:
ORCID: https://orcid.org/0000-0003-1504-9213
Marc Lipsitch
Funded by:
funder-id http://dx.doi.org/10.13039/100000030, centers for disease control and prevention;
Award ID: U01IP001121
Award Recipient
:
ORCID: https://orcid.org/0000-0003-1504-9213
Marc Lipsitch
Funded by:
funder-id http://dx.doi.org/10.13039/100000057, National Institute of General Medical Sciences;
Award ID: R01GM130668-02
Award Recipient
:
ORCID: https://orcid.org/0000-0002-4206-418X
Mauricio Santillana
PMD was supported by the fellowship Ramón Areces Foundation. JAH was funded by the
National Institute of General Medical Sciences, Award U54GM088558, and the National
Institutes of Health Director’s Early Independence, Award DP5-OD028145. ML was supported
by the Morris-Singer Fund and by a subcontract from the Carnegie Mellon University
under an award from the US Centers for Disease Control and Prevention, Award U01IP001121).
MS was supported by the National Institute Of General Medical Sciences, Award R01GM130668-02.
The funders had no role in study design, data collection and analysis, decision to
publish, or preparation of the manuscript.
Subject:
Research Article
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People and places
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Geographical locations
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Europe
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European Union
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Spain
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Biology and life sciences
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Organisms
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Viruses
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RNA viruses
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Coronaviruses
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SARS coronavirus
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SARS CoV 2
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Biology and life sciences
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Microbiology
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Medical microbiology
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Microbial pathogens
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Viral pathogens
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Coronaviruses
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SARS coronavirus
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SARS CoV 2
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Medicine and health sciences
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Pathology and laboratory medicine
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Pathogens
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Microbial pathogens
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Viral pathogens
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Coronaviruses
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SARS coronavirus
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SARS CoV 2
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Biology and life sciences
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Organisms
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Viruses
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Viral pathogens
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Coronaviruses
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SARS coronavirus
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SARS CoV 2
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Medicine and Health Sciences
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Epidemiology
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Disease Surveillance
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Infectious Disease Surveillance
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Medicine and Health Sciences
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Medical Conditions
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Infectious Diseases
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Infectious Disease Control
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Infectious Disease Surveillance
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Medicine and Health Sciences
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Epidemiology
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Medicine and Health Sciences
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Medical Conditions
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Infectious Diseases
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Physical Sciences
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Mathematics
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Probability Theory
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Statistical Distributions
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Distribution Curves
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Medicine and Health Sciences
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Public and Occupational Health
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Biology and Life Sciences
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Cognitive Science
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Cognitive Psychology
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Decision Making
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Biology and Life Sciences
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Psychology
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Cognitive Psychology
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Decision Making
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Social Sciences
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Psychology
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Cognitive Psychology
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Decision Making
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Biology and Life Sciences
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Cognitive Science
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Cognition
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Decision Making