The Efficacy and Safety of YAG Laser Vitreolysis for Symptomatic Vitreous Floaters of Complete PVD or Non-PVD

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Abstract

Introduction

To evaluate and compare the efficacy and safety of YAG laser vitreolysis in treating symptomatic vitreous floaters of complete posterior vitreous detachment (PVD) and non-PVD.

Methods

In this prospective cohort study, 51 eyes with symptomatic floaters were treated with YAG laser vitreolysis. Participants were divided into complete PVD and non-PVD groups. Objective visual quality measures including the Strehl ratio (SR), internal spherical aberration (SA), internal comatic aberration (CA), internal high-order aberration (HOA), area ratio of modulation transfer function (MTFa) and Vitreous Floaters Symptom Questionnaire (VFSQ-13) scores were used to compare the efficacy of YAG laser vitreolysis treatment between two groups.

Results

The mean age of all patients was 56.80 ± 10.82 years old. In total, 36 of 51 (70.59%; 95% CI 58.10–83.10) patients reported their symptoms as significant or complete improvement after YAG laser vitreolysis treatment. Post-treatment MTFa, internal SA and internal HOA were significantly better compared to baseline (26.19 ± 14.73 vs. 29.19 ± 17.98, p = 0.013; 0.05 ± 0.05 vs. 0.04 ± 0.04, p = 0.031 and 0.23 ± 0.22 vs. 0.16 ± 0.07, p = 0.044; respectively) in all eyes. Twenty-nine of 51 (56.86%) eyes had floaters of non-PVD type. Significant or complete subjective improvements in the PVD group and non-PVD group were 72.73% and 68.97% ( p = 0.344), respectively.

Conclusions

Improved subjective and objective visual quality in participants with symptomatic floaters following YAG laser vitreolysis was found in both groups. The efficacy of YAG laser vitreolysis was comparable in floaters of complete PVD and non-PVD types.

Supplementary Information

The online version contains supplementary material available at 10.1007/s40123-021-00422-6.

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Most cited references 40

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Article: not found

Repeatability of measurements with a double-pass system.

Alain Saad, Marc Saab, Damien Gatinel (2010)

To evaluate the repeatability of measurements with a double-pass system. Rothschild Foundation, Paris, France. Eyes were separated into 2 control groups ( 40 years), a post-refractive surgery group, and a cataract group. Measurements were performed using the Optical Quality Analysis System. The main outcome measures were the objective scattering index (OSI), the cutoff frequency of the modulation transfer function (MTF), and the Strehl ratio. The repeatability limit was obtained from the individual standard deviations. Forty-two eyes were evaluated. The mean OSI value was 0.47 +/- 0.11 (SD) in the younger control group, 1.73 +/- 0.26 in the older control group, 1.34 +/- 0.16 in the post-refractive surgery group, and 6.15 +/- 0.50 in the cataract group. The mean cutoff MTF value was 39.44 +/- 3.93 cycles per degree (cpd), 26.07 +/- 3.89 cpd, 28.34 +/- 2.84 cpd, and 13.3 +/- 1.69 cpd, respectively, and the mean Strehl ratio, 0.234 +/- 0.023, 0.146 +/- 0.021, 0.169 +/- 0.023, and 0.098 +/- 0.010, respectively. The repeatability limit for the whole population was 0.841 (33.5%) for the OSI, 8.499 (31.1%) for the cutoff MTF, and 0.051 (31%) for the Strehl ratio. The repeatability limit was good and equivalent for the OSI, the MTF, and the Strehl ratio values. There was a wide interval between the normal and pathologic threshold for OSI measurements, indicating that the reliability of the double-pass device complies with the requirements for quantitative assessment of scattering. No author has a financial or proprietary interest in any material or method mentioned. Copyright 2010 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

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Record: found
Abstract: found
Article: not found

Vitrectomy for floaters: prospective efficacy analyses and retrospective safety profile.

Laura C. Huang, Alfredo Sadun, Christianne A Wa … (2014)

Floaters impact vision but the mechanism is unknown. We hypothesize that floaters reduce contrast sensitivity function, which can be normalized by vitrectomy, and that minimally invasive vitrectomy will have lower incidences of retinal tears (reported at 30%) and cataracts (50-76%).

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Article: not found

Preclinical metrics to predict through-focus visual acuity for pseudophakic patients

Aixa Alarcón, Carmen Cánovas, Robert Rosen … (2016)

This study compares the clinical through-focus visual acuity (VA) in patients implanted with different intraocular lens (IOL) to optical bench testing of the same IOLs to evaluate the suitability of optical metrics of predicting clinical VA. Modulation transfer function and phase transfer function for different spatial frequencies and US Air Force pictures were measured using an optical bench for two monofocal IOLs, three multifocal IOLs and an extended range of vision IOL. Four preclinical metrics were calculated and compared to the clinical through-focus VA collected in three different clinical studies (243 patients in total). All metrics were well correlated (R2≥0.89) with clinical data and may be suitable for predicting through-focus VA in pseudophakic eyes.

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Author and article information

Contributors

Lijun Shen:

ORCID: http://orcid.org/0000-0002-7518-2932

slj@mail.eye.ac.cn

Journal

Journal ID (nlm-ta): Ophthalmol Ther

Journal ID (iso-abbrev): Ophthalmol Ther

Title: Ophthalmology and Therapy

Publisher: Springer Healthcare (Cheshire )

ISSN (Print): 2193-8245

ISSN (Electronic): 2193-6528

Publication date (Electronic): 15 November 2021

Publication date PMC-release: 15 November 2021

Publication date (Print): February 2022

Volume: 11

Issue: 1

Pages: 201-214

Affiliations

[1 ]GRID grid.268099.c, ISNI 0000 0001 0348 3990, Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical University, ; Wenzhou, Zhejiang China

[2 ]He Eye Specialist Hospital, Shenyang, Liaoning China

[3 ]GRID grid.233520.5, ISNI 0000 0004 1761 4404, Eye Institute of Chinese PLA, Department of Ophthalmology, , Xijing Hospital, Air Force Medical University, ; Xi’an, Shanxi China

[4 ]GRID grid.4777.3, ISNI 0000 0004 0374 7521, School of Mathematics and Physics, , Queens University Belfast, ; University Road, Belfast, BT7 1NN Northern Ireland, UK

Author information

Lijun Shen http://orcid.org/0000-0002-7518-2932

Article

Publisher ID: 422

DOI: 10.1007/s40123-021-00422-6

PMC ID: 8770727

PubMed ID: 34778916

SO-VID: faf80d5f-3057-45fc-b9a7-4c80b66b637c

License:

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

History

Date received : 9 August 2021

Date accepted : 1 November 2021

Funding

Funded by: FundRef http://dx.doi.org/10.13039/501100005047, Natural Science Foundation of Liaoning Province;

Award ID: 2020-MS-360

Award Recipient : Tiezhu Lin

Custom metadata

Keywords: floaters,posterior vitreous detachment,vitreolysis,weiss ring,yag laser

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Keywords: floaters, posterior vitreous detachment, vitreolysis, weiss ring, yag laser

The Efficacy and Safety of YAG Laser Vitreolysis for Symptomatic Vitreous Floaters of Complete PVD or Non-PVD

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Abstract

Introduction

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Conclusions

Supplementary Information

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Most cited references 40

Repeatability of measurements with a double-pass system.

Vitrectomy for floaters: prospective efficacy analyses and retrospective safety profile.

Preclinical metrics to predict through-focus visual acuity for pseudophakic patients

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