For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
1
views
29
references
 Top references
cited by
0
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      570
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Dosimetric comparison and evaluation of two computational algorithms in VMAT treatment plans

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Purpose

          This study aimed to assess the accuracy and dosimetric impact of the Acuros XB (AXB) algorithm compared to the Anisotropic Analytical Algorithm (AAA) in two situations. First, simple phantom geometries were set and analyzed; moreover, volumetric modulated arc therapy (VMAT) clinical plans for Head & Neck and lung cases were calculated and compared.

          Methods

          First, a phantom study was performed to compare the algorithms with radiochromic EBT3 film doses using one PMMA slab phantom and two others containing foam or air gap. Subsequently, a clinical study was conducted, including 20 Head & Neck and 15 lung cases irradiated with the VMAT technique. The treatment plans calculated by AXB and AAA were evaluated in terms of planning target volume (PTV) coverage (V 95%), dose received by relevant organs at risk (OARs), and the impact of using AXB with a grid size of 1 mm. Finally, patient‐specific quality assurance (PSQA) was performed and compared for 17 treatment plans.

          Results

          Phantom dose calculations showed a better agreement of AXB with the film measurements. In the clinical study, AXB plans exhibited lower Conformity Index and PTV V 95%, higher maximum PTV dose, and lower mean and minimum PTV doses for all anatomical sites. The most notable differences were detected in regions of intense heterogeneity. AXB predicted lower doses for the OARs, while the calculation time with a grid size of 1 mm was remarkably higher. Regarding PSQA, although AAA was found to exhibit slightly higher gamma passing rates, the difference did not affect the AXB treatment plan quality.

          Conclusions

          AXB demonstrated higher accuracy than AAA in dose calculations of both phantom and clinical conditions, specifically in interface regions, making it suitable for sites with large heterogeneities. Hence, such dosimetric differences between the two algorithms should always be considered in clinical practice.

          Related collections

          Most cited references29

          • Record: found
          • Abstract: found
          • Article: not found

          Stereotactic body radiation therapy: the report of AAPM Task Group 101.

          Stanley H. Benedict, Kamil M Yenice, David Followill … (2010)
          Task Group 101 of the AAPM has prepared this report for medical physicists, clinicians, and therapists in order to outline the best practice guidelines for the external-beam radiation therapy technique referred to as stereotactic body radiation therapy (SBRT). The task group report includes a review of the literature to identify reported clinical findings and expected outcomes for this treatment modality. Information is provided for establishing a SBRT program, including protocols, equipment, resources, and QA procedures. Additionally, suggestions for developing consistent documentation for prescribing, reporting, and recording SBRT treatment delivery is provided.
          Article 0 comments Cited 358 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Validation of a new grid-based Boltzmann equation solver for dose calculation in radiotherapy with photon beams.

            Mohammad Salehpour, G Failla, J McGhee … (2010)
            A new grid-based Boltzmann equation solver, Acuros, was developed specifically for performing accurate and rapid radiotherapy dose calculations. In this study we benchmarked its performance against Monte Carlo for 6 and 18 MV photon beams in heterogeneous media. Acuros solves the coupled Boltzmann transport equations for neutral and charged particles on a locally adaptive Cartesian grid. The Acuros solver is an optimized rewrite of the general purpose Attila software, and for comparable accuracy levels, it is roughly an order of magnitude faster than Attila. Comparisons were made between Monte Carlo (EGSnrc) and Acuros for 6 and 18 MV photon beams impinging on a slab phantom comprising tissue, bone and lung materials. To provide an accurate reference solution, Monte Carlo simulations were run to a tight statistical uncertainty (sigma approximately 0.1%) and fine resolution (1-2 mm). Acuros results were output on a 2 mm cubic voxel grid encompassing the entire phantom. Comparisons were also made for a breast treatment plan on an anthropomorphic phantom. For the slab phantom in regions where the dose exceeded 10% of the maximum dose, agreement between Acuros and Monte Carlo was within 2% of the local dose or 1 mm distance to agreement. For the breast case, agreement was within 2% of local dose or 2 mm distance to agreement in 99.9% of voxels where the dose exceeded 10% of the prescription dose. Elsewhere, in low dose regions, agreement for all cases was within 1% of the maximum dose. Since all Acuros calculations required less than 5 min on a dual-core two-processor workstation, it is efficient enough for routine clinical use. Additionally, since Acuros calculation times are only weakly dependent on the number of beams, Acuros may ideally be suited to arc therapies, where current clinical algorithms may incur long calculation times.
            Article 0 comments Cited 84 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Dosimetric validation of Acuros XB with Monte Carlo methods for photon dose calculations.

              K Bush, M P Gagne, W Ansbacher … (2011)
              The dosimetric accuracy of the recently released Acuros XB advanced dose calculation algorithm (Varian Medical Systems, Palo Alto, CA) is investigated for single radiation fields incident on homogeneous and heterogeneous geometries, and a comparison is made to the analytical anisotropic algorithm (AAA). Ion chamber measurements for the 6 and 18 MV beams within a range of field sizes (from 4.0 x 4.0 to 30.0 x 30.0 cm2) are used to validate Acuros XB dose calculations within a unit density phantom. The dosimetric accuracy of Acuros XB in the presence of lung, low-density lung, air, and bone is determined using BEAMnrc/DOSXYZnrc calculations as a benchmark. Calculations using the AAA are included for reference to a current superposition/convolution standard. Basic open field tests in a homogeneous phantom reveal an Acuros XB agreement with measurement to within +/- 1.9% in the inner field region for all field sizes and energies. Calculations on a heterogeneous interface phantom were found to agree with Monte Carlo calculations to within +/- 2.0% (sigmaMC = 0.8%) in lung (p = 0.24 g cm(-3)) and within +/- 2.9% (sigmaMC = 0.8%) in low-density lung (p = 0.1 g cm(-3)). In comparison, differences of up to 10.2% and 17.5% in lung and low-density lung were observed in the equivalent AAA calculations. Acuros XB dose calculations performed on a phantom containing an air cavity (p = 0.001 g cm(-3)) were found to be within the range of +/- 1.5% to +/- 4.5% of the BEAMnrc/DOSXYZnrc calculated benchmark (sigmaMC = 0.8%) in the tissue above and below the air cavity. A comparison of Acuros XB dose calculations performed on a lung CT dataset with a BEAMnrc/DOSXYZnrc benchmark shows agreement within +/- 2%/2mm and indicates that the remaining differences are primarily a result of differences in physical material assignments within a CT dataset. By considering the fundamental particle interactions in matter based on theoretical interaction cross sections, the Acuros XB algorithm is capable of modeling radiotherapy dose deposition with accuracy only previously achievable with Monte Carlo techniques.
              Article 0 comments Cited 75 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Contributors
                Kalliopi Platoni:
                ORCID: https://orcid.org/0000-0003-2977-7895
                polaplatoni@gmail.com
                Journal
                Journal ID (nlm-ta): J Appl Clin Med Phys
                Journal ID (iso-abbrev): J Appl Clin Med Phys
                Journal ID (doi): 10.1002/(ISSN)1526-9914
                Journal ID (publisher-id): ACM2
                Title: Journal of Applied Clinical Medical Physics
                Publisher: John Wiley and Sons Inc. (Hoboken )
                ISSN (Electronic): 1526-9914
                Publication date (Electronic): 21 June 2023
                Publication date Collection: September 2023
                Volume: 24
                Issue: 9 ( doiID: 10.1002/acm2.v24.9 )
                Electronic Location Identifier: e14051
                Affiliations
                [ 1 ] 2nd Department of Radiology, Medical Physics Unit, School of Medicine, Attikon University Hospital National and Kapodistrian University of Athens Athens Greece
                [ 2 ] 2nd Department of Radiology, Radiation Oncology Unit, School of Medicine, Attikon University Hospital National and Kapodistrian University of Athens Athens Greece
                Author notes
                [*] [* ] Correspondence

                Platoni Kalliopi, 2nd Department of Radiology, Medical Physics Unit, School of Medicine, National and Kapodistrian University of Athens, Attikon University Hospital, 12462 Athens, Greece.

                Email: polaplatoni@ 123456gmail.com

                Author information
                https://orcid.org/0000-0003-2977-7895
                Article
                Publisher ID: ACM214051
                DOI: 10.1002/acm2.14051
                PMC ID: 10476991
                PubMed ID: 37344987
                SO-VID: fb8549a5-ce61-4724-8e19-925563414ea4
                Copyright © © 2023 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, LLC on behalf of The American Association of Physicists in Medicine.
                License:

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                Date revision received : 29 April 2023
                Date received : 19 October 2022
                Date accepted : 15 May 2023
                Page count
                Figures: 7, Tables: 4, Pages: 14, Words: 7902
                Categories
                Subject: Radiation Oncology Physics
                Subject: Radiation Oncology Physics
                Custom metadata
                source-schema-version-number 2.0
                cover-date September 2023
                details-of-publishers-convertor Converter:WILEY_ML3GV2_TO_JATSPMC version:6.3.3 mode:remove_FC converted:04.09.2023

                Keywords: aaa,acuros xb,dose calculation,volumetric modulated arc therapy
                Data availability:
                Keywords: aaa, acuros xb, dose calculation, volumetric modulated arc therapy

                Comments

                Comment on this article