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      Interventions for sexual dysfunction following treatments for cancer in women

      1 , 2 , 3 , 4 , 1 , 5 , 6 , 1 , 7
      Cochrane Pain, Palliative and Supportive Care Group
      Cochrane Database of Systematic Reviews
      Wiley

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          Abstract

          The proportion of people living with and surviving cancer is growing. This has led to increased awareness of the importance of quality of life, including sexual function, in those affected by cancer. Sexual dysfunction is a potential long-term complication of many cancer treatments. This includes treatments that have a direct impact on the pelvic area and genitals, and also treatments that have a more generalised (systemic) impact on sexual function.This is an update of the original Cochrane review published in Issue 4, 2007, on interventions for treating sexual dysfunction following treatments for cancer for men and women. Since publication in 2007, there has been an increase in the number of trials for both men and women and this current review critiques only those for women. A review in press will present those for men.

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          Most cited references136

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          Diagnostic and Statistical Manual of Mental Disorders

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            Is Open Access

            Developing and evaluating complex interventions: the new Medical Research Council guidance

            Evaluating complex interventions is complicated. The Medical Research Council's evaluation framework (2000) brought welcome clarity to the task. Now the council has updated its guidance
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              The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function.

              This article presents the development of a brief, self-report measure of female sexual function. Initial face validity testing of questionnaire items, identified by an expert panel, was followed by a study aimed at further refining the questionnaire. It was administered to 131 normal controls and 128 age-matched subjects with female sexual arousal disorder (FSAD) at five research centers. Based on clinical interpretations of a principal components analysis, a 6-domain structure was identified, which included desire, subjective arousal, lubrication, orgasm, satisfaction, and pain. Overall test-retest reliability coefficients were high for each of the individual domains (r = 0.79 to 0.86) and a high degree of internal consistency was observed (Cronbach's alpha values of 0.82 and higher) Good construct validity was demonstrated by highly significant mean difference scores between the FSAD and control groups for each of the domains (p < or = 0.001). Additionally, divergent validity with a scale of marital satisfaction was observed. These results support the reliability and psychometric (as well as clinical) validity of the Female Sexual Function Index (FSFI) in the assessment of key dimensions of female sexual function in clinical and nonclinical samples. Our findings also suggest important gender differences in the patterning of female sexual function in comparison with similar questionnaire studies in males.
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                Author and article information

                Journal
                146518
                Cochrane Database of Systematic Reviews
                Wiley
                14651858
                July 2022
                February 02 2016
                : 2022
                : 7
                Affiliations
                [1 ]Marie Curie Palliative Care Research Department, Division of Psychiatry; University College London; London UK
                [2 ]Yealth Network; Beijing Yealth Technology Co., Ltd; Beijing China
                [3 ]Cochrane Campbell Global Ageing Partnership; London UK
                [4 ]School of Psychology; Queen's University Belfast; Belfast UK
                [5 ]UCL Division of Psychiatry; University College London; London UK
                [6 ]Department of Women's Cancer; The UCL Elizabeth Garrett Anderson Institute for Women's Health; London UK
                [7 ]Marie Curie Hospice; London UK
                Article
                10.1002/14651858.CD005540.pub3
                26830050
                ff926087-df9d-467d-88e4-1c302ebb16dc
                © 2016
                History

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