Dose-volume effect relationships for late rectal morbidity in patients treated with chemoradiation and MRI-guided adaptive brachytherapy for locally advanced cervical cancer: Results from the prospective multicenter EMBRACE study.

Mazeron, Renaud; Fokdal, Lars U.; Kirchheiner, Kathrin; Georg, Petra; Jastaniyah, Noha; Segedin, Barbara; Mahantshetty, Umesh; Hoskin, Peter; Jürgenliemk-Schulz, Ina; Kirisits, Christian; Lindegaard, Jacob C; Dörr, Wolfgang; Haie-Meder, Christine; Tanderup, Kari; Pötter, Richard

doi:10.1016/j.radonc.2016.06.006

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Dose-volume effect relationships for late rectal morbidity in patients treated with chemoradiation and MRI-guided adaptive brachytherapy for locally advanced cervical cancer: Results from the prospective multicenter EMBRACE study.

Author(s): Renaud Mazeron, Lars U. Fokdal, Kathrin Kirchheiner, Petra Georg, Noha Jastaniyah, Barbara Segedin, Umesh Mahantshetty, Peter Hoskin, Ina Jürgenliemk-Schulz, Christian Kirisits, Jacob C Lindegaard, Wolfgang Dörr, Christine Haie-Meder, Kari Tanderup, Richard Pötter

Publication date: 2016-09-01

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Publisher: Elsevier BV

Keywords: Normal tissue complication probability, Rectal morbidity, Rectal bleeding, Proctitis, MRI-guided adaptive brachytherapy, Locally advanced cervical cancer, Fistula,

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Abstract

To establish dose volume-effect relationships predicting late rectal morbidity in cervix cancer patients treated with concomitant chemoradiation and MRI-guided adaptive brachytherapy (IBABT) within the prospective EMBRACE study.