With approximately 40% of the London building stock built before 1919, internal wall insulation (IWI) is one of the likely measures for deep retrofit to meet carbon emissions targets. However, IWI can lead to moisture accumulation and associated unintended consequences, especially in walls highly exposed to wind-driven rain (WDR). Climate change is predicted to exacerbate WDR exposure. This paper presents a comparative analysis between the hygrothermal performance of IWI under current and far future (2080) climates. Historic weather station data and UKCP18 climate projections were used to develop weather files for simulating current and future climate, respectively. Hygrothermal simulations were performed using DELPHIN. Assemblies include calcium silicate, phenolic foam, and wood fibre systems. Future climate predictions are associated with a rise of interstitial relative humidity, leading to patterns more favourable to mould growth.