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      Blood Flow Patterns In The Ascending Aorta after TAVI And Surgical Aortic Valve Replacement: A Study Using 4D Flow MRI

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            Abstract

            Background Transcatheter aortic valve implantation (TAVI) is a new method for treating patients with severe aortic stenosis with high risk for or rejected from conventional heart surgery. Its impact on blood flow patterns and parameters in the ascending aorta are unknown. Using 4-dimensional phase contrast MRI (4D Flow MRI) we examined the hemodynamics in the ascending aorta after TAVI and compared them to stented bioprostheses and healthy controls. Methods We used 4D Flow MRI (spatial resolution 1.8x1.8x2.5mm3; temporal resolution 13-22 phases/heart cycle) of the ascending aorta in 14 patients with TAVI (mean age 76 years, 8 males, all Edwards Sapien), 12 patients with different stented bioprostheses (mean age 77 years, 8 males) and 9 healthy controls (mean age 55 years, 8 males) controls using a 1.5T MR system. We examined the distribution of the maximum systolic wall shear stresses as well as the maximum blood flow velocities in the mid-ascending aorta. Results Patients with TAVI and stented bioprosthesis revealed an asymetric distribution of the wall shear stresses with significantly elevated values at the anterior and right-anterior curvature and significantly lower values at the posterior curvature compared to the healthy controls. Concerning the maximum velocities both TAVI and stented bioprostheses revealed an asymetric distribution along the right-anterior curvature where TAVI showed a more anterior distribution compared to the healty controls which showed a central distribution. Conclusion The blood flow patterns in patients with TAVI and stented bioprostheses differs significantly from the ones in healthy controls. However, TAVI and stented bioprosthesis showed small but significant regional differences.

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            Author and article information

            Conference
            ScienceOpen Posters
            ScienceOpen
            October 14 2014
            Author information
            https://orcid.org/0000-0003-3827-8895
            Article
            10.14293/P2199-8442.1.SOP-MED.P0LOW9.v1
            03183066-9d7d-4c3f-babd-23183db12583

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

            25th European Students' Conference
            History

            Medicine
            TAVI, Aortic Valve Replacement, 4D Flow, Cardiac MRI, Wall Shear Stress, Aortic Stenosis, Blood Flow, Ascending Aorta, Velocity

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