<b>Spike protein related adverse effects and the need for more focused, if not individualized approach in COVID-19 vaccination programs </b>

Aim of this review is to discuss the need for more focused, if not individualized COVID-19 vaccination approach with a goal to prevent serious adverse effects and to establish high quality vaccination programs according to the principles of precision medicine.

Content

Author and article information

Journal

Title: ScienceOpen Preprints

Publisher: ScienceOpen

Publication date (Electronic preprint): 22 April 2022

Affiliations

[1 ] Clinical pharmacology and toxicology, UHC Split, Soltanska 1, Croatia

Author notes

[* ]Email: domina.petric@ 123456gmail.com .

Author information

Domina Petric https://orcid.org/0000-0001-5609-1675

Article

DOI: 10.14293/S2199-1006.1.SOR-.PPCTEV6.v1

SO-VID: 6504ae8b-99ad-4903-a6d7-19978eb5f24f

License:

This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .

History

Date received : 22 April 2022

Data availability: Data sharing not applicable to this article as no datasets were generated or analysed during the current study.

ScienceOpen disciplines: Medicine

Keywords: covid19,vaccines,adverse effects,precision medicine

References

Aldén Markus, Olofsson Falla Francisko, Yang Daowei, Barghouth Mohammad, Luan Cheng, Rasmussen Magnus, De Marinis Yang. Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line. Current Issues in Molecular Biology. Vol. 44(3):1115–1126. 2022. MDPI AG. [Cross Ref]
Shakoor Muhammad Tariq, Birkenbach Mark P., Lynch Matthew. ANCA-Associated Vasculitis Following Pfizer-BioNTech COVID-19 Vaccine. American Journal of Kidney Diseases. Vol. 78(4):611–613. 2021. Elsevier BV. [Cross Ref]
Kampf Günter. The epidemiological relevance of the COVID-19-vaccinated population is increasing. The Lancet Regional Health - Europe. Vol. 11:2021. Elsevier BV. [Cross Ref]
Kundu Rhia, Narean Janakan Sam, Wang Lulu, Fenn Joseph, Pillay Timesh, Fernandez Nieves Derqui, Conibear Emily, Koycheva Aleksandra, Davies Megan, Tolosa-Wright Mica, Hakki Seran, Varro Robert, McDermott Eimear, Hammett Sarah, Cutajar Jessica, Thwaites Ryan S., Parker Eleanor, Rosadas Carolina, McClure Myra, Tedder Richard, Taylor Graham P., Dunning Jake, Lalvani Ajit. Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts. Nature Communications. Vol. 13(1)2022. Springer Science and Business Media LLC. [Cross Ref]

Comments

Comment on this article

[1] Aldén Markus, Olofsson Falla Francisko, Yang Daowei, Barghouth Mohammad, Luan Cheng, Rasmussen Magnus, De Marinis Yang. Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line. Current Issues in Molecular Biology. Vol. 44(3):1115–1126. 2022. MDPI AG. [Cross Ref]

[2] Shakoor Muhammad Tariq, Birkenbach Mark P., Lynch Matthew. ANCA-Associated Vasculitis Following Pfizer-BioNTech COVID-19 Vaccine. American Journal of Kidney Diseases. Vol. 78(4):611–613. 2021. Elsevier BV. [Cross Ref]

[3] Kampf Günter. The epidemiological relevance of the COVID-19-vaccinated population is increasing. The Lancet Regional Health - Europe. Vol. 11:2021. Elsevier BV. [Cross Ref]

[4] Kundu Rhia, Narean Janakan Sam, Wang Lulu, Fenn Joseph, Pillay Timesh, Fernandez Nieves Derqui, Conibear Emily, Koycheva Aleksandra, Davies Megan, Tolosa-Wright Mica, Hakki Seran, Varro Robert, McDermott Eimear, Hammett Sarah, Cutajar Jessica, Thwaites Ryan S., Parker Eleanor, Rosadas Carolina, McClure Myra, Tedder Richard, Taylor Graham P., Dunning Jake, Lalvani Ajit. Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts. Nature Communications. Vol. 13(1)2022. Springer Science and Business Media LLC. [Cross Ref]