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      Spike protein related adverse effects and the need for more focused, if not individualized approach in COVID-19 vaccination programs

      Preprint
      In review
      research-article
        1 ,
      ScienceOpen Preprints
      ScienceOpen
      covid19, vaccines, adverse effects, precision medicine
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            Abstract

            Aim of this review is to discuss the need for more focused, if not individualized COVID-19 vaccination approach with a goal to prevent serious adverse effects and to establish high quality vaccination programs according to the principles of precision medicine.

            Content

            Author and article information

            Journal
            ScienceOpen Preprints
            ScienceOpen
            22 April 2022
            Affiliations
            [1 ] Clinical pharmacology and toxicology, UHC Split, Soltanska 1, Croatia
            Author notes
            Article
            10.14293/S2199-1006.1.SOR-.PPCTEV6.v1
            6504ae8b-99ad-4903-a6d7-19978eb5f24f

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .


            Data sharing not applicable to this article as no datasets were generated or analysed during the current study.
            Medicine
            covid19,vaccines,adverse effects,precision medicine

            References

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            2. Shakoor Muhammad Tariq, Birkenbach Mark P., Lynch Matthew. ANCA-Associated Vasculitis Following Pfizer-BioNTech COVID-19 Vaccine. American Journal of Kidney Diseases. Vol. 78(4):611–613. 2021. Elsevier BV. [Cross Ref]

            3. Kampf Günter. The epidemiological relevance of the COVID-19-vaccinated population is increasing. The Lancet Regional Health - Europe. Vol. 11:2021. Elsevier BV. [Cross Ref]

            4. Kundu Rhia, Narean Janakan Sam, Wang Lulu, Fenn Joseph, Pillay Timesh, Fernandez Nieves Derqui, Conibear Emily, Koycheva Aleksandra, Davies Megan, Tolosa-Wright Mica, Hakki Seran, Varro Robert, McDermott Eimear, Hammett Sarah, Cutajar Jessica, Thwaites Ryan S., Parker Eleanor, Rosadas Carolina, McClure Myra, Tedder Richard, Taylor Graham P., Dunning Jake, Lalvani Ajit. Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts. Nature Communications. Vol. 13(1)2022. Springer Science and Business Media LLC. [Cross Ref]

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