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      A comprehensive comparison between COVID-19 vaccines: a review

      Preprint
      In review
      research-article
        1 ,   1 , , 2
      ScienceOpen Preprints
      ScienceOpen
      Vaccines, COVID-19
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            Abstract

            COVID-19 started in December 2019 in Wuhan and spread worldwide. The cause of COVID-19 is the newly discovered coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Until now, this pandemic is affecting almost every country in the world and over 100 million cases were confirmed. It is expected that vaccination could be a beneficial way to control and protect against COVID-19. This review aimed to compare 4 platforms of COVID-19 vaccines and used recently developed vaccines candidates as examples to illustrate. Safety, efficacy, scaling, cost, and adaptation to the mutated virus were included. Theoretical and clinical vaccine research results were used and we attempted to conclude the advantage and disadvantage of each candidate platform. Countries should choose an appropriate vaccine for their people and satisfy the demand for vaccines.

            Content

            Author and article information

            Journal
            ScienceOpen Preprints
            ScienceOpen
            24 June 2021
            Affiliations
            [1 ] Imperial College London, London, UK
            [2 ] Chongqing Depu Foreign Language School, Chongqing, China
            Author notes
            Article
            10.14293/S2199-1006.1.SOR-.PPUC2QO.v1
            e724878d-2879-4837-a954-c15fac6dece8

            This work has been published open access under Creative Commons Attribution License CC BY 4.0 , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com .


            Data sharing not applicable to this article as no datasets were generated or analysed during the current study.
            Medicine,Immunology,Life sciences,Infectious disease & Microbiology
            Vaccines,COVID-19

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