Our study aims to determine the epidemiological, clinical, paraclinical, and evolutionary profiles of chronic kidney failure among dialysis patients treated at the Nephrology Department at the State University Hospital of Haiti.This is a cross-sectional study based on patients diagnosed with chronic kidney failure who are followed in the Nephrology Department of the State University Hospital of Haiti. Inclusion criteria were having laboratory tests and/or ultrasound and/or a diagnostic renal biopsy of chronic kidney failure available between January 2015 and September 2019. We used probabilistic simple random sampling. Data were collected in Excel and processed by Epi Info 7 and SPSS software 20.The mean age was 47.57 years ± 14.18 with a M/F sex ratio of 1, 66. The mean creatinine level was 8.011 mg/dl ± 5.4657 and the average hemoglobin level was 8.7213 g/dl ± 1.9356. The most represented clinical signs were hypertension and edema, respectively (70.5% and 52.29%) of cases. 52.5% of our patients were at the terminal stage. Vascular nephropathy was the leading cause of chronic kidney failure (55%). The majority of our patients were at an advanced stage of the disease, 37, 5% at a severe stage and 52, 5% at a terminal age.62, 5 % developed a complication during their follow-up. Dual or higher therapy was preferred and ACE inhibitors were used in 45.1%. Furthermore, 65% of patients were still on hemodialysis and the fatality rate was 10%.Chronic kidney failure can be prevented by early detection and proper treatment of hypertension and diabetes.