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Ion and Energy Metabolism of the Brain at the Cellular Level

edited-book

Author(s): Leif Hertz , Arne Schousboe

Publication date (Print): 1975

Publisher: Elsevier

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The effect of sodium ions on the electrical activity of the giant axon of the squid

A. L. Hodgkin, Benjamin B Katz (1949)

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Brain metabolism during fasting.

Andrew Kemp, R. E. Owen, P Morgan … (1967)

Catheterization of cerebral vessels in three obese patients undergoing 5-6 wk of starvation demonstrated that beta-hydroxybutyrate and acetoacetate replaced glucose as the predominant fuel for brain metabolism. A strikingly low respiratory quotient was also observed, suggesting a carboxylation mechanism as a means of disposing of some of the carbon of the consumed substrates.