ScienceOpen:
research and publishing network
For Publishers
Discovery
Metadata
Peer review
Hosting
Publishing
For Researchers
Join
Publish
Review
Collect
My ScienceOpen
Sign in
Register
Dashboard
Blog
About
Search
Advanced search
My ScienceOpen
Sign in
Register
Dashboard
Search
Search
Advanced search
For Publishers
Discovery
Metadata
Peer review
Hosting
Publishing
For Researchers
Join
Publish
Review
Collect
Blog
About
0
views
0
references
Top references
cited by
0
Cite as...
0 reviews
Review
0
comments
Comment
0
recommends
+1
Recommend
0
collections
Add to
0
shares
Share
Twitter
Sina Weibo
Facebook
Email
829
similar
All similar
Record
: found
Abstract
: not found
Book Chapter
: not found
Three Carbon-Heteroatom Bonds: Acid Halides; Carboxylic Acids and Acid Salts
The Pummerer Rearrangement
other
Author(s):
A. J. Phillips
,
C. E. Love
Publication date
(Online):
2007
Publisher:
Georg Thieme Verlag KG
Read this book at
Publisher
Buy book
Review
Review book
Invite someone to review
Bookmark
Cite as...
There is no author summary for this book yet. Authors can add summaries to their books on ScienceOpen to make them more accessible to a non-specialist audience.
Related collections
ScienceOpen Research
Author and book information
Book Chapter
Publication date (Print):
2007
Publication date (Online):
2007
Page
: 1
DOI:
10.1055/sos-SD-020-00770
SO-VID:
5a2f94b5-f1a0-4b57-b2d1-328034f7588c
History
Data availability:
Comments
Comment on this book
Sign in to comment
Book chapters
pp. 1
Synthesis of Acylselenenyl Halides
pp. 1
Direct Condensation of Acids and Alcohols Catalyzed by a Lewis Acid
pp. 1
Catalytic Enantioselective Sulfanylation of β-Oxo Esters
pp. 1
The Prévost Reaction
pp. 1
Treatment with Oxalyl Chloride
pp. 1
Cleavage of α-Cyano Esters by Decyanation
pp. 1
Synthesis of Product Subclass 4
pp. 1
Kinetic Enzymatic Resolution of Racemic 2-Fluoroalkanoates
pp. 1
Using Thallium Carboxylate Salts
pp. 1
Ring Opening of Lactams
pp. 1
Selenium- and Tellurium-Based Anhydrides
pp. 1
Molybdenum-Catalyzed Asymmetric Allylic Alkylation of Azlactones
pp. 1
Acyl Disulfides (Acyl Dithioperoxides)
pp. 1
Electrochemical Oxidation with Ruthenium(IV) Oxide
pp. 1
Oxidation Using Iodine or Bromine
pp. 1
From Hydroxysuccinic Acid Esters
pp. 1
Chiral Aluminum–Salen Complex Catalyzed Strecker Synthesis
pp. 1
Acylation of Magnesium Methyl Malonate with 1-Acylimidazoles
pp. 1
Other Palladium-Complex-Catalyzed Cross Couplings
pp. 1
SAr Reaction of 2-(Methoxyaryl)dihydrooxazoles
pp. 1
Synthesis from Iodotelluride
pp. 1
Synthesis by Wittig Reaction
pp. 1
Electrochemical Carboxylation of Iodoarenes
pp. 1
Palladium-Mediated Oxidation of Silyl Enol Ethers
pp. 1
Addition of Trihalomethanesulfenyl Acetates to Alkenes
pp. 1
Acylation by Carboxylic Acid Esters
pp. 1
Synthesis from Thioesters
pp. 1
Rearrangement of Allylic Trichloroacetimidates
pp. 1
Claisen Rearrangement
pp. 1
Miscellaneous Carboxylations with Carbon Dioxide
pp. 1
From Acetals
pp. 1
Thermal Rearrangement of Allylic Trichloroacetimidates on a Chiral Template
pp. 1
Using Trichloroisocyanuric Acid
pp. 1
Copper-Catalyzed Carboxylation of Alk-1-ynes with Carbon Dioxide and Alkyl Bromides
pp. 1
Carboxylation of Arylmetal Species
pp. 1
Synthesis of Product Subclass 3
pp. 1
Asymmetric Addition to Camphorsultam-Based Oximes
pp. 1
Curtius Rearrangement of α,α-Dialkyl β-Ester Carboxylic Acids
pp. 1
Electrocarboxylation of Chloroacetone
pp. 1
Succinate Esters by Carbonylation
pp. 1
Ring Aromatization Using Trifluoroacetic Acid
pp. 1
Hydrolysis of 2,2-Dihalo Acid Halides
pp. 1
Oxidative Cleavage of an Alkynol
pp. 1
Applications of Product Subclass 4 in Organic Synthesis
pp. 1
Via Nucleophilic Aromatic Substitution on Malonyl–Iron–Arene Complexes
pp. 1
Birch Reduction
pp. 1
Applications of Product Subclass 1 in Organic Synthesis
pp. 1
Introduction of the α-Amino Group: Rearrangement of α,α-Dialkyl-β-carbonyl Carboxylic Acid Esters
pp. 1
Synthesis from Enol Ethers
pp. 1
Rhodium-Catalyzed Addition of Arylboronic Acids to -(-Butylsulfinyl)imino Esters
pp. 1
Introduction of the Side Chain: Addition to Glycine Cations
pp. 1
Applications of Benzeneselenenyl Trifluoroacetate
pp. 1
Alkylation of - and -Imidazolidinones
pp. 1
Miscellaneous Methods
pp. 1
Diacyl Disulfides
pp. 1
Base-Promoted Cleavage of Diaryl Ketones
pp. 1
Barton's Radical Decarboxylation
pp. 1
Carboxylation of Metalated Alk-1-ynes
pp. 1
Acylation of Malonates
pp. 1
Synthesis by Resolution
pp. 1
Kolbe–Schmitt Reaction
pp. 1
Aromatization
pp. 1
Diels–Alder Reaction
pp. 1
Fluoride-Mediated Cleavage of Silyl Esters
pp. 1
Addition of a Silyl Ketene Acetal to a 1,3-Dioxolan-2-ylium Cation
pp. 1
Intramolecular Nucleophilic Addition to Epoxides Using Trichloroacetimidate
pp. 1
Synthesis from Acylsulfenyl Chlorides and Sulfur Nucleophiles
pp. 1
Carbenoid Dimerization
pp. 1
Asymmetric Addition to Chiral Oximes
pp. 1
Friedel–Crafts Acylation of Buta-1,3-dienes, Arenes, and Hetarenes
pp. 1
Baeyer–Villiger Oxidation
pp. 1
Carbonylation Reactions of Formates with Organic Halides
pp. 1
Using Isobutene
pp. 1
Electrochemical Carboxylations
pp. 1
Via the Monoacid Chloride
pp. 1
Favorskii Rearrangement
pp. 1
3-Amino-3-oxyalkanoic Acid Esters
pp. 1
-Acylhydroxylamines and Related Compounds
pp. 1
Hydroesterification with Formate Esters
pp. 1
Regioselective Alkylation of Alkynoic Acids
pp. 1
Using Sodium Perborate
pp. 1
Catalytic Asymmetric Bromination with Chiral Bis(dihydrooxazole)–Copper(II) Complexes
pp. 1
Hydroesterifications Catalyzed by Transition-Metal Complexes
pp. 1
Using Silicon Nucleophiles
pp. 1
Synthesis of Product Subclass 8
pp. 1
2-Fluoroalkanoic Acids
pp. 1
Asymmetric Alkylation
pp. 1
2,3-Epoxyalkanoates
pp. 1
Lewis Acid Catalyzed Acylation
pp. 1
With Conservation of the Carbon Skeleton
pp. 1
Alkenation Reactions
pp. 1
Addition of the Lithium Enolate of an Ester to 1-Alkanoyl-1-pyrroles
pp. 1
3-Phenylcyclobutanone -Benzoyloxime from Hydroxylamine and Benzoyl Chloride
pp. 1
Metalation/Alkoxycarbonylation of Alkenyl Ethers, Sulfides, and Enecarbamates
pp. 1
Carboxylation with Formate or Its Derivatives
pp. 1
Cleavage of 2-Haloethyl Esters
pp. 1
Wittig and Related Alkenylations
pp. 1
From -Diols with Sodium Sulfide
pp. 1
Chiral Salicylamine Catalyzed Strecker Reaction
pp. 1
α,β-Didehydroamino Acid Esters
pp. 1
Grignard Additions to Alkylidenemalonates
pp. 1
Oxidation Using the Jones Reagent
pp. 1
Oxidation of Primary Alcohols
pp. 1
Hydrolysis of 2-Alkyl-4,5-dihydrooxazoles
pp. 1
Heterogeneous Hydrogenations
pp. 1
Alkylation with Strong Base and an Alkylating Agent
pp. 1
Alkylation of Chiral -Pyrrolidine Amides
pp. 1
Modifications of Propynoic Acid Esters or Derivatives
pp. 1
Metathesis with Tungsten-Based Catalysts
pp. 1
Succinate Esters by Stobbe Condensations
pp. 1
Treatment with Pyridinium Poly(hydrogen fluoride)/Dicyclohexylcarbodiimide
pp. 1
Introduction of the α-Amino Group: Electrophilic Amination of Enolates
pp. 1
Rearrangement of Zinc Enolates (The Reformatsky–Claisen Rearrangement)
pp. 1
Introduction of the Carboxylate: Addition of Nitrile or α-Bromo Ester Enolates to Imines (Strecker and Darzens Syntheses)
pp. 1
Addition of a Silyl Ketene Acetal to 2-Ethoxy-2-methyl-1,3-dioxolane
pp. 1
Synthesis by Rearrangement
pp. 1
Transesterification with Chemical Catalysis
pp. 1
With Ruthenium(III) Chloride and Potassium Persulfate
pp. 1
Conjugate Addition of Organocopper Reagents
pp. 1
Erlenmeyer Condensation
pp. 1
Carbonylation of Arylboranes with Carbon Monoxide
pp. 1
Acyl Peroxide Mediated Oxidation
pp. 1
Oxidation Using Oxygen
pp. 1
Treatment with Thionyl Chloride
pp. 1
-Aroylhydroxylamines from Aroyl Cyanides or Aroyl Chlorides
pp. 1
Succinate Esters by Reduction of Butenedioates
pp. 1
Using Ozone
pp. 1
Suzuki Coupling of β-Bromoamidoacrylates with Aryl- and Vinylboronic Acids
pp. 1
Using Chiral Imines
pp. 1
Butyrolactones from 1,3-Unsaturated Esters
pp. 1
Ring-Opening Reactions
pp. 1
Electrophilic Esterification
pp. 1
Rearrangement of (Alkanoylsulfanyl)acetates
pp. 1
Synthesis from Activated Esters
pp. 1
Transformation of Allylsilanes into Allylamines via Phenyltellurinylation
pp. 1
-Aryl--benzoylhydroxylamines by Reaction of -Arylhydroxylamines with Benzoyl Chloride
pp. 1
Hydrometalation–Carboxylation Sequence
pp. 1
Diels–Alder Cycloaddition Reactions of Chiral Nitroso Compounds
pp. 1
Using Potassium Permanganate
pp. 1
Using Mixed Anhydrides
pp. 1
Alkylation of Bis-lactim Ethers
pp. 1
Using Wittig-Type Reactions
pp. 1
Hydrolysis of Arenedinitriles
pp. 1
Fluorination of 1,3-Dicarbonyl Derivatives
pp. 1
Introduction of the α-Amino Group
pp. 1
From Furan
pp. 1
Reductive Carboxylation of Alkynes
pp. 1
Transition-Metal-Catalyzed Cross Couplings of Alk-2-enoic Acid Esters
pp. 1
Diastereoselective Palladium-Catalyzed Rearrangement of Allylic Trichloroacetimidates
pp. 1
Using Acid Chlorides
pp. 1
Radical-Based Methods
pp. 1
Alkylation of Dihydroimidazol-4-ones
pp. 1
Alcoholysis of Meldrum's Acid with -Butyl Alcohol
pp. 1
Carboxylation of Alk-1-ynes
pp. 1
Proton-Catalyzed Lactonization
pp. 1
Trifluoroacetoxy-λ-selanes from Selenoxides
pp. 1
Oxidation Using a Peroxide
pp. 1
Intermolecular Nucleophilic Addition to Chiral Epoxides
pp. 1
Sonogashira Coupling
pp. 1
Heck Coupling of Amidoacrylates with Aryl and Vinyl Halides
pp. 1
Lactones from Heterocyclic Precursors
pp. 1
Cycloaddition of Alkynoic Acids
pp. 1
Conversion of α-Oxo Esters into 2-Alkoxy- and 2-Aminoalk-2-enoic Acid Esters
pp. 1
Isomerizations
pp. 1
Acylation by Carboxylic Acids
pp. 1
Lead-Mediated Reactions
pp. 1
Oxidation of Propargylic Alcohols or Aldehydes
pp. 1
Using an Indium Hydride Complex
pp. 1
Reaction with Acid Chlorides
pp. 1
Carbometalation/Carboxylation of Alkynes
pp. 1
Introduction of Carboxylate: Asymmetric Addition of Nitriles to Imines (Strecker Synthesis)
pp. 1
Synthesis from Ketenes
pp. 1
Ring-Closing Metathesis
pp. 1
Via Monoalkylation of Malonate Diesters
pp. 1
Alkylation–Decarboxylation of Methanetricarboxylates
pp. 1
Use of Metals in Protic Solvents as Reducing Agents
pp. 1
Oxidation/Reduction Processes
pp. 1
Group 1 Metal Carboxylic Acid Salts
pp. 1
Using Solid-Supported Permanganate Salts
pp. 1
Conjugate Addition of Boronate Derivatives
pp. 1
Hydrolysis of 2,2-Diheteroatom-Substituted Amides
pp. 1
Light-Induced Cleavage
pp. 1
From Pyrolysis of Malonate Diels–Alder Adducts
pp. 1
Metathesis with Ruthenium-Based Catalysts
pp. 1
Electrophilic Amination of Chiral Enolates Using Sulfonyl Azides
pp. 1
Using Electrochemical Oxidation
pp. 1
Oxidation of a Chiral Enolate
pp. 1
Addition to Benzyne Intermediates
pp. 1
Selective Reduction of Dicarbonyl Compounds
pp. 1
Synthesis from Carboxylic Acids
pp. 1
Nucleophilic Addition of Alcohols
pp. 1
Carboxylic Acid Anhydrides
pp. 1
Using Bromosuccinimide
pp. 1
From Oxalyl Chloride
pp. 1
Aryl(oxo)acetic Acids by Hydrolysis of Indole-2,3-diones
pp. 1
The von Richter Rearrangement
pp. 1
Rhodium-Mediated Reactions
pp. 1
With Acetaldehyde and Acetic Anhydride
pp. 1
Bromination of Alkanoic Acids with -Bromosuccinimide
pp. 1
Introduction of the Nitrogen and Carboxylate Groups
pp. 1
Aluminum–Salen-Catalyzed Aldol Reactions of 5-Alkoxyoxazoles
pp. 1
Deconjugate Alkylation
pp. 1
Synthesis of Product Subclass 8
pp. 1
Free-Radical Addition
pp. 1
Oxidative Cleavage of 2-Chlorobuta-1,3-diene
pp. 1
Using Sodium or Calcium Hypochlorites
pp. 1
2-Oxo and 2-(Oxyimino) Acids by Hydrolysis of the Corresponding Esters
pp. 1
Halide-Exchange Reactions of Acid Chlorides
pp. 1
O-Alkylation of a 2-Hydroxyalkanoate
pp. 1
Horner–Emmons Condensation
pp. 1
-Acetyl--allyl--pent-4-enoylhydroxylamine from -Acetyl--allylhydroxylamine
pp. 1
Direct Amination of Enolates with Azodicarboxylates
pp. 1
Esterification of Oxalic Acid by the Fischer Method
pp. 1
Malonate Esters by Claisen Condensations with Oxalic Acid Esters
pp. 1
Enzyme-Catalyzed Enantioselective Reduction
pp. 1
Asymmetric Hydrogenations
pp. 1
Transesterification
pp. 1
Anionic [3+3] Aromatic Ring Formation with Chan's Diene
pp. 1
Alkenation of α-Oxo Acids
pp. 1
Alcoholysis of 2,2-Diheteroatom-Substituted Nitriles
pp. 1
Using the Evans–Tishchenko Reaction
pp. 1
Palladium-Catalyzed Asymmetric Allylic Alkylation of Azlactones
pp. 1
Using Imidates
pp. 1
Other Methods
pp. 1
Addition of 2-Sulfanylphenol to Alkyl Penta-2,3-dienoates
pp. 1
δ-Lactones from the Addition of C Building Blocks to Carbonyl Compounds
pp. 1
Oxidation of Aromatic Aldehydes
pp. 1
Using a Morpholinium Salt as Catalyst
pp. 1
Succinate Esters by Stereoselective [2,3]-Wittig Rearrangement
pp. 1
Using Chloroformates
pp. 1
Dicarbonylation of Terminal Alkenes and Cycloalkenes
pp. 1
Carbonylation Reactions
pp. 1
Ring Opening of Epoxides
pp. 1
Lactonization
pp. 1
Metathesis with Molybdenum-Based Catalysts
pp. 1
Introduction of the Side Chain: Alkylation of Glycine and Related Enolates
pp. 1
Proline Organocatalysis
pp. 1
Oxidative Addition
pp. 1
Chiral Manganese(III)–Salen Catalyzed Enantioselective Epoxidation of -α,β-Unsaturated Esters
pp. 1
Using Nickel Boride Catalysts
pp. 1
Synthesis by Homologation
pp. 1
Treatment with 1-Fluoro-,,2-trimethylprop-1-en-1-amine
pp. 1
Alkylation of Chiral Acyclic Schiff Bases
pp. 1
Oxidation with Hypervalent Iodine
pp. 1
Homologation by Multiple Carbon Atoms
pp. 1
Reaction of Cyclic Phosphites with β-Dicarbonyl Compounds
pp. 1
Synthesis of Product Subclass 10
pp. 1
Addition to α,β-Unsaturated Esters
pp. 1
From Chiral Allylic Carbonates
pp. 1
Of Aryl Halides
pp. 1
Synthesis from Alk-2-enoic Acid Esters by Bromination–Dehydrobromination
pp. 1
Conversion of Cyclobutanone -Benzoyloximes into Nitriles
pp. 1
Oxidative Cleavage of Unsaturated Carboxylic Acids
pp. 1
Friedel–Crafts Carboxylation
pp. 1
Via Acid Chloride Intermediates
pp. 1
Transition-Metal-Catalyzed Oxidations
pp. 1
Using Caro's Acid
pp. 1
2-Haloalkanoic Acids
pp. 1
Synthesis of Selenocarboxylic -Acids and Tellurocarboxylic -Acids
pp. 1
Opening Cyclic Sulfates
pp. 1
Synthesis from Carboxylic Acids
pp. 1
Malonate Esters by Conjugate Additions to Malonate Derivatives
pp. 1
Allylic Acyloxylation with Double-Bond Migration
pp. 1
Oxidative Dimerization of Titanium Enolates
pp. 1
Synthesis of Product Subclass 12
pp. 1
Hydrolysis of Thiazoles
pp. 1
Acylation of Dialkyl Malonates with Acid Chlorides
pp. 1
Nucleophilic Displacement of Sulfonic Esters and Cyclic Sulfates
pp. 1
Aldol Condensations between Pyruvic Acid and Benzaldehydes
pp. 1
2-Iodoalkanoates
pp. 1
Horner–Wittig Reaction
pp. 1
Cyclopropanation of Functionalized Alkenes
pp. 1
Hydrocarboxylation with Carbon Monoxide
pp. 1
Palladium-Catalyzed Hydroxycarbonylation of Alkenyl Electrophiles
pp. 1
Use of the Lithium Enolate of Bis(trimethylsilyl) Malonate
pp. 1
Transition-Metal-Catalyzed Carbonylation of Haloarenes
pp. 1
Of Vinyl Halides
pp. 1
Synthesis by Hydrolysis
pp. 1
β-Lactones by [2+2]-Cycloaddition Reactions
pp. 1
Hydrolysis of Acid Anhydrides
pp. 1
Using Miscellaneous Reagents
pp. 1
Fluoride-Catalyzed O-Acylation of Enolates
pp. 1
Halolactonization
pp. 1
(Phenylselanyl)- and (Phenylsulfanyl)lactonization
pp. 1
Cope Rearrangement of Silyl Cyanohydrins
pp. 1
Alkoxycarbonylation of Alkyl Halides Promoted by Acids
pp. 1
Electrophilic Amination of Chiral Enolates Using Azodicarboxylates
pp. 1
Diastereoselective Michael Addition to Nitroalkenes
pp. 1
Synthesis of α,β-Didehydroamino Acids through Elimination
pp. 1
Using Iodine
pp. 1
Using Diazoalkanes
pp. 1
Asymmetric Diels–Alder Addition to Chiral Imino Esters; Chiral Menthyl Derivatives
pp. 1
Use of a Cationic Scandium Lewis Acid
pp. 1
With Zinc(II) Permanganate
pp. 1
α,β-Didehydroamino Acids
pp. 1
Other Syntheses
pp. 1
ω-Alkynoic Acids and Aromatic Acids by Addition–Elimination
pp. 1
Haloalkanoic Acid Esters
pp. 1
Malonic Acids by Nucleophilic Acyl Substitution
pp. 1
Lithium–Halogen Exchange with Haloarenes
pp. 1
By Brønsted Acids
pp. 1
Acylation of 3-Oxoalkanoic Acid Esters
pp. 1
Reductive Metalation of Haloarenes
pp. 1
Catalytic Asymmetric Fluorination of α-Cyano Esters by Treatment with Chiral Palladium Complexes and -Fluorobis(phenylsulfonyl)amine
pp. 1
Direct Halogenation of Thiocarboxylic -Acids or Their Salts
pp. 1
Electrophilic Amination of Chiral Silyl Enol Ethers with Azodicarboxylates
pp. 1
Sigmatropic Rearrangements
pp. 1
Using Other Carbon Nucleophiles
pp. 1
α-Alkylation of Preformed Alk-2-enoic Acid Esters
pp. 1
Hydrocarboxylation without Carbon Monoxide
pp. 1
With Palladium on Carbon and Oxygen
pp. 1
Sigmatropic Rearrangement of Allyl Trihaloacetates
pp. 1
Oxalic Acid by Oxidative Methods
pp. 1
Direct Fluorination of Peptides Containing Tyrosine
pp. 1
Reaction of Enamines with Nitroalkenes
pp. 1
Synthesis from Carboxylic Acid Derivatives
pp. 1
Malonate Displacements
pp. 1
Reactions of Carboxylic Acids or Trialkylsilyl Carboxylate Esters with Dibromotriphenylphosphorane
pp. 1
Microwave Hydrolysis of Meldrum's Acid Derivatives
pp. 1
Hydrohalogenation Reactions of Substituted Allenoates
pp. 1
Hofmann Rearrangement of α,α-Dialkyl β-Amido Esters
pp. 1
Oxidation of Enolates with Oxaziridines
pp. 1
From Halocyclobutenes
pp. 1
Base-Catalyzed Hydrolysis
pp. 1
Homologation by One Carbon Atom
pp. 1
Allylic Acyloxylation without Double-Bond Migration
pp. 1
With Paraformaldehyde and Copper(II) Acetate
pp. 1
Synthesis from α-Hydroxy Carbonyl Compounds and 1,2-Diones
pp. 1
Reduction of Ethyl 3-Oxo-2-(triphenylphosphoranylidene)alkanoates
pp. 1
Palladium-Mediated Oxidative Coupling of Carbon Monoxide
pp. 1
Introduction of the Side Chain: Alkylation of Chiral Amino Acid Enolates
pp. 1
From Thiiranes
pp. 1
Synthesis of Product Subclass 2
pp. 1
Acetyl Hypohalites
pp. 1
Oxidation of the C=C Bond of Enynes
pp. 1
Reduction of Double Bonds
pp. 1
Alkoxycarbonylation of Organometallic Compounds
pp. 1
Using Enzymes
pp. 1
Optically Active Isoxazolidin-5-ones from Nitrones
pp. 1
Dicarbonylation of But-2-enes
pp. 1
Nucleophilic Substitution at the α-Carbon of 2,2-Diheteroatom-Substituted Esters
pp. 1
Oxidation with Sodium Bromate
pp. 1
Knoevenagel and Doebner-Modified Knoevenagel Condensations
pp. 1
Direct Metalation
pp. 1
Reduction Using Samarium(II) Iodide
pp. 1
Non-Group 1 Metal Carboxylic Acid Salts
pp. 1
Via Lithium Enolates
pp. 1
Reactions of Carboxylate Esters and Anhydrides with Hydrogen Fluoride or Hydrogen Fluoride/Pyridine
pp. 1
Metal-Mediated C—C Bond Formation
pp. 1
Oxidation Reactions
pp. 1
Fluorination Using Acetyl Hypofluorite
pp. 1
Using the Homo Aldol–Tishchenko Reaction
pp. 1
Oxidation of Benzylic Ethers
pp. 1
Oxidation of Aldehydes
pp. 1
Direct Alkylation of Alkanoic and Alkenoic Acids
pp. 1
Oxidation with Cobalt
pp. 1
By Solid Acids
pp. 1
Succinic Acids by Allylic Alkylation
pp. 1
Nucleophilic Amination of 2,3-Epoxy Alcohols Using Diazidotitanium(IV) Diisopropoxide
pp. 1
Resolution
pp. 1
Diastereofacial Selective Epoxidation
pp. 1
From Dibromosuccinic Acid Esters with Dimethylformamide
pp. 1
O-Acylation of Aldehyde Enolates Derived from Alkynoate Anions
pp. 1
Phase-Transfer-Catalyzed Dialkylation of Malonates
pp. 1
Direct Elimination of Water from Carboxylic Acids
pp. 1
Construction of the Aromatic Ring by Anionic Methods
pp. 1
Photochemical Oxidation
pp. 1
2-Alkoxyalkanoates
pp. 1
2-Alkoxyalkanoic Acids
pp. 1
Synthesis from Ketones via the Baeyer–Villiger Reaction
pp. 1
Oxidation by Halonium-Generating Combinations
pp. 1
Synthesis by Reduction
pp. 1
Rearrangement of Ketene Acetals Derived from Selenoxides
pp. 1
Of Benzyl Halides
pp. 1
Synthesis of Product Subclass 1
pp. 1
Oxidation of α-Oxo Ketones
pp. 1
Oxidation with Nickel
pp. 1
Cross-Coupling Reactions Catalyzed by Transition-Metal Complexes
pp. 1
Amine Carboxylic Acid Salts
pp. 1
Arylation of Thiocarboxylic Acids
pp. 1
With Potassium or Sodium Dichromate
pp. 1
Conjugate Addition to Alk-2-ynoic Acid Esters
pp. 1
Synthesis of Product Subclass 4
pp. 1
Alkene Metathesis
pp. 1
Acid Chlorides
pp. 1
Phosphine Additions to Butynedioates
pp. 1
From Nitroalkanes
pp. 1
Reaction of Thiocarboxylic -Acids and Electrophilic Acylsulfanyl Donors
pp. 1
Alkylation at C3 of a Chiral β-Lactam
pp. 1
Synthesis of Product Subclass 5
pp. 1
Using Hydrogen Peroxide
pp. 1
Stereoselective Reduction of 2-Oxoalkanoic Acids and Esters
pp. 1
2-Tellanylalkanoic acids
pp. 1
Insertion of Carbon Monoxide into Arenediazonium Salts
pp. 1
Synthesis from Acetals
pp. 1
Rearrangement of O-Acylated Azlactones
pp. 1
Rearrangement of Ketene Acetals Derived from Ortho Esters (The Johnson Protocol)
pp. 1
Malonate Esters by Dichlorination of Malonates with Trifluoromethanesulfonyl Chloride
pp. 1
Synthesis of Product Subclass 2
pp. 1
Using Imidazoles
pp. 1
With Palladium(II) and Oxygen
pp. 1
Markovnikov Hydroacyloxylation Using Carboxylic Acids
pp. 1
Oxidation of Alk-2-enoates
pp. 1
α-Alkyl-α-aminoalkanoic Acid Esters
pp. 1
Reaction with Sodium Nitrite and Acetic Acid
pp. 1
From Lithiophosphoranes
pp. 1
Synthesis by Conjugate Addition
pp. 1
The Favorskii Rearrangement
pp. 1
[3,3] Rearrangements of Allylic Esters
pp. 1
The Trost Method
pp. 1
Ring Opening
pp. 1
5-Amino-1,3-dioxanes as Chiral Auxiliaries
pp. 1
Metal-Catalyzed Carboxylation of Haloarenes
pp. 1
From -Diols via Thermal Elimination
pp. 1
Synthesis of Product Subclass 8
pp. 1
Using Acid Chlorides and 4-Benzylpyridine as an Activator
pp. 1
Coupling of Alk-1-ynes with Bromopropynoic Acid (Cadiot–Chodkiewicz Reaction)
pp. 1
Synthesis from Nitriles
pp. 1
Lithium–Halogen Exchange
pp. 1
Chiral Salicylamine-Based Strecker Synthesis
pp. 1
3,3-Dioxyalkanoic Acid Esters
pp. 1
Electrochemical Oxidation
pp. 1
Photolysis of Chromium–Carbene Complexes
pp. 1
Using Pyridinium Chlorochromate
pp. 1
Alkylation of Cyclic Imines
pp. 1
Aldol-Type Condensations
pp. 1
Ring Opening of Cyclopropanes
pp. 1
Alkylation of Menthol Derivatives
pp. 1
Oxidation of 3-Oxo-2-(triphenylphosphoranylidene)propanoates
pp. 1
Alkylation of Oxazaborolidinones
pp. 1
Hydrolysis of Esters
pp. 1
Acylation of Ethyl Hydrogen Malonate
pp. 1
From -Diols via 1,3-Dioxolanes
pp. 1
Cleavage Reactions
pp. 1
Cleavage of β-Oxo Esters
pp. 1
Introduction of the Side Chain: Rearrangements
pp. 1
Addition of 2,2-Dimethyl-1,3-dioxane-4,6-dione to Acylating Agents
pp. 1
Deaminative Chlorination (Chlorodediazoniation) of α-Amino Acids
pp. 1
Acylation of a Sulfur Source
pp. 1
Cationic Rhodium Complexes of P-Chirogenic Phosphines
pp. 1
Miscellaneous Oxidations with 2,2,6,6-Tetramethylpiperidin-1-oxyl
pp. 1
Oxidation of Enol Ethers
pp. 1
Malonic Acids by Cyanation of Chloroacetic Acid
pp. 1
Acylation of Phenols
pp. 1
Using Manganese(IV) Oxide and Sodium Cyanide
pp. 1
-Alkyl--benzoylhydroxylamines by Reduction of Oxime Benzoates
pp. 1
Carboxylation of Alkenyl Organometallics
pp. 1
Oxidation of Alkylarenes
pp. 1
Alkylation of -Butyloxazolidinones
pp. 1
Alkoxycarbonylation of Organotransition-Metal Compounds
pp. 1
Chiral 2-Sulfanylalkanoic Acids
pp. 1
α-Oxo Acids by Oxidative Cleavage of 2-Alkylidene-Substituted Carboxylic Acids
pp. 1
Using Manganese Oxides
pp. 1
Intramolecular Nucleophilic Addition to Epoxides
pp. 1
Anhydride Cleavage
pp. 1
Asymmetric Conjugate Addition
pp. 1
Synthesis by Reaction of Carboxylate Anions
pp. 1
Hydrostannation
pp. 1
Oxidation of Aldehydes
pp. 1
Using -Iodosuccinimide
pp. 1
Using Ruthenium(VIII) Oxide
pp. 1
Synthesis from Acid Chlorides
pp. 1
Dithioxo Anhydrides from Naphthalic Anhydride
pp. 1
Palladium-Catalyzed Carbonylation/Alkoxylation of Alkenyl Electrophiles
pp. 1
Oxidation of α-Hydroxycarboxylic Acids
pp. 1
Oxidation Using a Peroxy Acid
pp. 1
Direct Esterification of Alk-2-ynoic Acids
pp. 1
Oxidation of Thiocarboxylic Acid -Esters
pp. 1
Alkoxycarbonylation of Alkenyl Organometallics
pp. 1
Transition-Metal-Mediated Cleavage of Allyl Esters
pp. 1
C-Acylation Using Magnesium Oxide
pp. 1
Introduction of the Side Chain: Claisen Rearrangement
pp. 1
Synthesis of Product Subclass 10
pp. 1
Miscellaneous Reactions
pp. 1
Metalation
pp. 1
Oxo/Thioxo Anhydrides by Cyclization of Aromatic Compounds with Adjacent Methyl and Carboxylic Acid Substituents
pp. 1
Displacement of Trifluoromethanesulfonates
pp. 1
Simple Metalation
pp. 1
Carboxylation of 1,1-Dibromoalkenes
pp. 1
Oxidation with 2,2,6,6-Tetramethylpiperidin-1-oxyl
pp. 1
Use of Aluminum Hydride Reducing Agents
pp. 1
Catalytic Asymmetric C—C Bond-Forming Reactions
pp. 1
Arndt–Eistert and Related Reactions
pp. 1
Catalytic Enantioselective Hydrogenation of 2-(Aryloxy)but-2-enoic Acids
pp. 1
Asymmetric Hydrogenation of Dehydropiperazinediones
pp. 1
Addition to α,β-Unsaturated Acids
pp. 1
Chlorination of Carboxylic Acids
pp. 1
Applications of Product Subclass 2 in Organic Synthesis
pp. 1
Cope Rearrangement
pp. 1
Oxidation Using Hydrogen Peroxide
pp. 1
Friedel–Crafts Acylation
pp. 1
Tandem Chlorination/Esterification of Acid Halides
pp. 1
Diastereoselective Ester Enolate Claisen Rearrangement
pp. 1
Asymmetric Conjugate Reduction
pp. 1
Application to the Synthesis of a Pharmaceutical Agent
pp. 1
Synthesis of Product Subclass 9
pp. 1
Reaction of Thiocarboxylic Acids and an Acylating Agent
pp. 1
Electrochemical Oxidation with Mercury and Oxygen
pp. 1
Synthesis of Acyl Diselenides, Acyl Ditellurides, and Mixed Chalcogen Derivatives
pp. 1
Photolysis of Chromium–Carbene Complexes
pp. 1
Oxidation of Methyl Ketones
pp. 1
With Sodium Permanganate
pp. 1
Synthesis by Oxidation Mediated by Metallic Salts
pp. 1
Kinetic Resolution
pp. 1
Butenolides from Furans
pp. 1
From Tartrates via Phosphinate Activation
pp. 1
Introduction of the Side Chain: Cycloaddition to C=C Bonds
pp. 1
Synthesis by Biotransformations
pp. 1
Transition-Metal-Catalyzed Hydrocarboxylation
pp. 1
5,6-Diphenyltetrahydro-1,4-oxazin-2-one Alkylation
pp. 1
Fluorination with 2-Fluoro-1,3,2-benzodithiazole 1,1,3,3-Tetraoxide
pp. 1
Synthesis from a Thiocarboxylic -Acid and an Electrophilic Selenium or Tellurium Fragment
pp. 1
Alkylation of Chiral Acyloxazolidinones
pp. 1
Reaction of Carboxylic Acids with Alkynyliodonium Salts
pp. 1
The Pummerer Rearrangement
pp. 1
Using Azide via Chiral (Trichloromethyl)methanols
pp. 1
Intramolecular Cyclization of ω-(Bromoalkyl)malonates
pp. 1
Hypervalent Iodine(V)
pp. 1
Enzymatic Hydrolysis
pp. 1
Deaminative Fluorination (Fluorodediazoniation) of Chiral α-Amino Acids
pp. 1
Bromination/Dehydrobromination of Alk-2-enoic Acids
pp. 1
Esterification of Malonic Acids
pp. 1
Reaction of Fluorinated Alkenes and Trimethyl Orthoacetate
pp. 1
-Acyl Selenothioperoxides and Tellurothioperoxides
pp. 1
Spiro Lactones by Oxidative Cyclization
pp. 1
Alkylation of Chiral Acyclic Schiff Bases
pp. 1
3,3-Dioxyalkanoic Acids
pp. 1
Synthesis of Product Subclass 1
pp. 1
Treatment with 2,4,6-Trifluoro-1,3,5-triazine
pp. 1
Addition of Metalated Propynoic Acid to Electrophiles
pp. 1
Using 1,1-Dichloroalkenes
pp. 1
Addition of Methyl Ketones to Carbonyl Compounds
pp. 1
C=C Addition Reactions
pp. 1
From Cyclobutanones
pp. 1
Trihalomethanesulfenyl Acetates and Trifluoroacetates from Sulfenyl Chlorides
pp. 1
Schmidt Rearrangement of β-Oxo Esters
pp. 1
Oxidation Reactions
pp. 1
Semihydrogenation
pp. 1
Synthesis of Product Subclass 7
pp. 1
Acetoacetylation of Alcohols Using Diketene
pp. 1
Addition of the Carboxy Group to Dithioates
pp. 1
Alkylation of Chiral Bis-lactim Ethers
pp. 1
Oxidation
pp. 1
Acetoxylation of Nitrogen Heterocycles
pp. 1
Asymmetric Hydrogenation
pp. 1
Alkylation of Chiral Nickel Complexes
pp. 1
With Manganese(IV) Phosphate
pp. 1
Palladium-Catalyzed Allylation of Glycine Derivatives
pp. 1
Synthesis from Carboxylate Esters
pp. 1
Via Grignard Reagents
pp. 1
Via Mixed Sulfonic Anhydrides
pp. 1
Using Heteropolyacids as Catalysts
pp. 1
Butenedioic Acids by Aldol Condensation
pp. 1
Ozonolysis
pp. 1
Conjugate Addition of Organoborane Reagents
pp. 1
Catalytic Asymmetric Mannich Additions to Imino Esters
pp. 1
Activation of Acid Chlorides with Methyl(2-pyridyl)carbamoyl Chloride
pp. 1
Formation of Thioacetals
pp. 1
Oxidation of 2,2-Diheteroatom-Substituted Aldehydes
pp. 1
The Keck Method
pp. 1
Hydrolysis of a 2,2-Diheteroatom-Substituted Thioester
pp. 1
Lewis Base Catalyzed Acylation
pp. 1
Michael Addition
pp. 1
Horner–Wadsworth–Emmons Reaction
pp. 1
Photooxygenation
pp. 1
Tandem Ene/Intramolecular Diels–Alder Reaction
pp. 1
Synthesis from Aldehydes
pp. 1
Electrophilic Fluorination with Acetyl Hypofluorite
pp. 1
Aryl(oxo)acetic Acids by Oxidation of 1-Aryl-2-nitroethanols
pp. 1
Introduction of the α-Amino Group: Electrophilic Amination of Enolates
pp. 1
Using Chiral -Acylhydrazones
pp. 1
Mannich-Type Reaction of Electron-Rich Aromatic Compounds with Chiral Imino Lactones
pp. 1
Rearrangement of Ketene Silyl Acetals (The Ireland–Claisen Rearrangement)
pp. 1
The Arndt–Eistert Reaction
pp. 1
Under Photostimulation
pp. 1
Memory of Chirality Alkylations
pp. 1
Synthesis of Product Subclass 3
pp. 1
Oxidation by Stoichiometric Transition-Metal Reagents
pp. 1
Synthesis from Thiocarboxylic -Acids and Electrophilic Amine Sources
pp. 1
Synthesis of Product Subclass 2
pp. 1
From Substituted Benzo[]furan
pp. 1
Synthesis of Arene-1,2-dicarboxylic Acid Esters by Diels–Alder Reaction Followed by Aromatization
pp. 1
Using (Diacyliodo)arenes
pp. 1
Enzyme-Catalyzed Ring Opening
pp. 1
Via Carboxylate Phosphorus Intermediates
pp. 1
Synthesis from Thiocarboxylic Acids
pp. 1
Eschenmoser Sulfide Contraction
pp. 1
2-Fluoroalkanoates
pp. 1
Oxidative C=C Bond Cleavage
pp. 1
Alkylation of - and -Oxazolidinones
pp. 1
Using an Organometallic Auxiliary
pp. 1
By Bases
pp. 1
Baeyer–Villiger Oxidation of Monocyclic, Annulated, and Spirocyclic Ketones
pp. 1
Oxidation of Thiocarboxylic -Acids
pp. 1
Synthesis of Product Subclass 12
pp. 1
Stobbe Condensation
pp. 1
From Lactones
pp. 1
Selanylation of Enolates
pp. 1
3-Hydroxy- and 3-Sulfanylalkanoic Acids and Derivatives
pp. 1
Lithiation of -Alkyl Substituents of Arene Carboxylic Acids
pp. 1
With Ruthenium(III) Chloride and Trichloroisocyanuric Acid
pp. 1
2-Chloroalkanoates
pp. 1
Chemoselective Hydrogenations
pp. 1
Miscellaneous Methods
pp. 1
Phase-Transfer-Catalyzed Michael Addition of Malonate Enolates
pp. 1
Carboxyalkyl α-Aminoalkylphosphonic Acid Monoesters from Spirophosphoranes
pp. 1
Anti-Markovnikov Hydroacyloxylation via Hydroboration
pp. 1
From Monohalosuccinic Acid Esters
pp. 1
Cross Coupling with Lithium α-Halocarboxylates
pp. 1
α-Aminoalkanoic Acids
pp. 1
Cationic Rhodium Complexes of Chiral -Symmetric Bisphosphinites
pp. 1
Synthesis of Product Subclass 9
pp. 1
Macrolactones by Baeyer–Villiger Oxidation
pp. 1
Introduction of the Side Chain: Additions to Oximes and Imino Esters
pp. 1
Achiral 2-Sulfanylalkanoic Acids
pp. 1
Using Other Benzoic Acid Anhydrides
pp. 1
Alkylation of Galactodialdehyde Aldimines
pp. 1
Acid-Catalyzed Hydrocarboxylation (Koch Reaction)
pp. 1
Carboxylation of Arenediazonium Salts
pp. 1
Copper-Mediated Reactions
pp. 1
Nonselective Hydrogenation
pp. 1
Homogeneous Hydrogenations
pp. 1
Oxidation of Arenes with Annulated Alcohols, Ketones, or Anhydrides
pp. 1
Carboxylation of Methyl Ketones
pp. 1
Benzeneselenenyl Trifluoroacetate from Benzeneseleninic Anhydride and Diphenyl Diselenide
pp. 1
Radical-Mediated Transformations of 2-Halo-Substituted Esters
pp. 1
Use of Di--butyl Dicarbonate
pp. 1
Enzymatic Esterification
pp. 1
Reaction of Cyanohydrins with Butenedioates
pp. 1
Asymmetric Tandem Bromination/Esterification of Acid Chlorides
pp. 1
Using Hydrosilane Reagents
pp. 1
Transition-Metal-Catalyzed Oxidation
pp. 1
Hydrolysis of 2,2-Diheteroatom-Substituted Esters
pp. 1
Using Oxone
pp. 1
Sulfinimine-Mediated Strecker Synthesis
pp. 1
Malonate Esters by Arylation of Malonate Derivatives
pp. 1
1,3-Allylic Rearrangement of a Chiral Acetal
pp. 1
From Dihalocyclobutanones
pp. 1
Electrocarboxylation with Carbon Dioxide
pp. 1
C-Acylation Using Soft Enolization
pp. 1
Introduction of the Side Chain: Diels–Alder Cycloaddition Reactions
pp. 1
Enantioselective Ester Enolate Claisen Rearrangement
pp. 1
Reduction of Alkylidenemalonates with Sodium Cyanoborohydride
pp. 1
Rhodium(I)-Catalyzed Asymmetric Reductive Amination of α-Oxo Acids
pp. 1
Alkylations of Alkyl Alkanoates
pp. 1
Synthesis of Selenides by Nucleophilic Substitution
pp. 1
α-Alkyl-α-aminoalkanoic Acids
pp. 1
From Lithio Dianions of Acetic Acid
pp. 1
2-Iodoalkanoic Acids by Treatment with Iodine and Chlorosulfonic Acid
pp. 1
Deaminative Dehydration of α-Diazo-β-hydroxy Esters Derived from Aldehydes
pp. 1
Alkylation of Chiral Cyclic Enolates
pp. 1
Reductive Alkoxycarbonylation of Alkynes
pp. 1
Synthesis from Carboxylic Acid Hydrazides
pp. 1
Synthesis of Product Subclass 7
pp. 1
Malonate Esters by Knoevenagel Condensation of Malonates
pp. 1
Nucleophilic Amination of α,β-Epoxy Acids Using Ammonia
pp. 1
Asymmetric Diels–Alder Reaction
pp. 1
Conjugate Addition of Other Carbon Nucleophiles
pp. 1
Hydration of Alk-2-ynoic Acids
pp. 1
Synthesis of Product Subclass 1
pp. 1
Synthesis of Product Subclass 4
pp. 1
Oxidation Using a Bis(1,3-diketonato)nickel(II) Complex and Oxygen
pp. 1
Via Mixed Carbonic Anhydrides
pp. 1
Wittig Reaction
pp. 1
Via Ethoxymagnesium Malonates
pp. 1
Hydrolysis of Peroxy Esters in the Presence of Bis(tributyltin) Oxide
pp. 1
Lactonization To Give Six-Membered Lactones
pp. 1
Of Allyl Halides
pp. 1
Using the Hetero Aldol–Tishchenko Reaction
pp. 1
Oxo(phenyl)acetic Acids by Acylation of Benzenes
pp. 1
Cyanation/Hydrolysis of Haloarenes
pp. 1
Oxalate Esters by Nucleophilic Acyl Substitution on Activated Oxalyl Derivatives
pp. 1
Enantioselective Hydrogenation of α-Fluoro-α,β-unsaturated Acids
pp. 1
Cycloadditions of Alk-2-ynoic Acid Esters
pp. 1
Resolution with Enzymatic Catalysis
pp. 1
Thioanhydrides (Diacyl Sulfides)
pp. 1
Reduction of Triple Bonds
pp. 1
Sulfur-Based Anhydrides
pp. 1
Addition of Allyltrimethylsilane
pp. 1
From 4-Nitrostyrene
pp. 1
Addition to α,β-Unsaturated Compounds
pp. 1
Other Methods
pp. 1
Pentafluorosulfur Peroxy Esters from Acyl Fluorides and Pentafluoro-λ-sulfane Hydroperoxide
pp. 1
Direct Condensation of Acids and Alcohols Using Ammonium Salts
pp. 1
Synthesis of Product Subclass 16
pp. 1
Transition-Metal-Mediated Alkylations
pp. 1
Electrochemical Oxidation with Nickel(II) Hydroxide
pp. 1
The Corey–Nicolaou Method
pp. 1
Synthesis by Modification of the Acyl Group
pp. 1
Mitsunobu Lactonization
pp. 1
Rearrangement of Ketene Acetals
pp. 1
Base-Catalyzed Deconjugation
pp. 1
3-Aryl-2-oxopropanoic Acids by Hydrolysis of 4-(Arylmethylene)oxazol-5(4)-ones
pp. 1
Conversion of β-Oxo Esters into 3-Alkoxy- and 3-Aminoalk-2-enoic Acid Esters
pp. 1
Oxidation with Palladium
pp. 1
Hydrolysis of 1,1,1-Trihalides
pp. 1
Synthesis from Acid Halides
pp. 1
Synthesis by Alkene Isomerization
pp. 1
From Aspartate Esters
pp. 1
Via Other Organometallic Reagents
pp. 1
Synthesis of Secondary Amines
pp. 1
Intramolecular Hydroacylation Reactions
pp. 1
From Tartrates via Cyclic Sulfates
pp. 1
Metal-Catalyzed Alkoxycarbonylation of Alkynes
pp. 1
Using Ethyl Chloroformate
pp. 1
Macrocyclic Multi-λ-tellanes by Reaction of a Telluronium Salt with Phthalate Salts
pp. 1
Reaction of [(Alkoxycarbonyl)methylene]triphenylphosphoranes with Acyl Chlorides, Anhydrides, or Carboxylic Acids
pp. 1
Diacetoxylation of Dienes by Acetoxytelluration Followed by Acetylation
pp. 1
Oxidation with Polyoxometalates
pp. 1
Non-Enzymatic Resolution
pp. 1
Synthesis of Product Class 6
pp. 1
Semihydrogenation of Alk-2-ynoic Acid Esters
pp. 1
Using Phosphine-Based Reagents
pp. 1
Electrochemical Oxidation with Silver and Oxygen
pp. 1
Electrophilic Bromination of Carbon Nucleophiles
pp. 1
Hydroformylation
pp. 1
Claisen Condensation of Acetates
pp. 1
Oxidation of Conjugated Ynals or Synthetic Equivalents
pp. 1
Selenocarboxylic Acid -Esters and Tellurocarboxylic Acid -Esters by Alkylation of Chalcogenocarboxylic Acids
pp. 1
Lactonization To Give Four-Membered Lactones
pp. 1
2-Hydroxyalkanoic Acids
pp. 1
Oxidative Processes
pp. 1
Epoxidation and Rearrangement of Alk-2-enoic Esters
pp. 1
Other Routes
pp. 1
Oxidation of 2,3-Epoxyalkan-1-ols
pp. 1
Synthesis of -Hydroxy Peptides
pp. 1
Synthesis of Product Subclass 13
pp. 1
Asymmetric Alkylation of 2-Hydroxyacetates
pp. 1
Using Transition-Metal Catalysts
pp. 1
Oxidation of a Preexisting Alcohol or Aldehyde Function
pp. 1
Oxidative Coupling
pp. 1
Reaction with Enolates
pp. 1
"Ex-novo" Oxidative Insertion of the Ester Function
pp. 1
Addition of the Carboxylate Group: Rearrangements
pp. 1
Selenocarboxylic Acid -Esters and Tellurocarboxylic Acid -Esters
pp. 1
2-Chloroalkanoic Acids
pp. 1
Using Chromium Oxides
pp. 1
Ring Opening under Acidic Conditions
pp. 1
Using Acid Chlorides in the Presence of Pyridinium Bases
pp. 1
Reaction with Benzylic Carbanions
pp. 1
One-Pot Method for Alkene Trifunctionalization
pp. 1
Substitution of Halogen
pp. 1
Phosphine-Catalyzed Internal Redox Isomerization of Alk-2-ynoic Acid Esters to Dienoic Acid Esters
pp. 1
Conjugate Addition of Enolates
pp. 1
Esterification of Succinic Acid
pp. 1
Addition of Metalated Propynoic Acid Esters to Electrophiles
pp. 1
Diastereoselective Organocuprate Michael Addition to Chiral Piperazine-2,5-dione Acceptors
pp. 1
Catalytic Asymmetric Aza-Henry Addition to Imino Esters
pp. 1
Chiral Binuclear Zirconium-Complex-Catalyzed Strecker Synthesis
pp. 1
Use of Magnesium Methyl Carbonate
pp. 1
Reactions with Enolates
pp. 1
Nucleophilic Addition to π-Allylpalladium Intermediates
pp. 1
Asymmetric Dihydroxylation Followed by Lactonization
pp. 1
Acylation of Methyl Acetoacetate with Acid Chlorides
pp. 1
Introduction of the α-Amino Group: Nucleophilic Addition of Nitrogen to Electrophiles
pp. 1
Alkylation at the α-Carbon of a Chiral β-Lactam
pp. 1
Metal-Mediated Glycine Enolate Alkylation
pp. 1
Reaction of [(Ethoxycarbonyl)iodomethyl]triphenylphosphonium Iodide with Aldehydes
pp. 1
Hydrolysis Reactions
pp. 1
Oxalate Esters by Oxidative Methods
pp. 1
Electrophilic Fluorination of Alkanoates
pp. 1
Synthesis from Alkyl Formates
pp. 1
Hofmann Rearrangement of α,α-Dialkyl-β-amido Esters
pp. 1
Using Homogeneous Palladium Catalysts
pp. 1
Reductive Alkylation
pp. 1
[3+2]-Dipolar Cycloaddition Reactions
pp. 1
Introduction of the Side Chain: Reductive Methods
pp. 1
Oxidation Using Rhenium(VII) Oxide and -Butyl Hydroperoxide
pp. 1
Unsaturated δ-Lactones from Glycals
pp. 1
Nucleophilic Substitutions
pp. 1
Enantioselective Palladium-Catalyzed Rearrangement of Prochiral Allylic Trichloroacetimidates
pp. 1
Deaminative Bromination (Bromodediazoniation) of Chiral α-Amino Acids
pp. 1
Use of a Fluorous Lewis Acid Catalyst
pp. 1
Introduction of the Side Chain: Addition to C=N Bonds
pp. 1
Direct Thiation of Carboxylic Acids
pp. 1
Miscellaneous Routes
pp. 1
Butyrolactones from Epoxides and C Building Blocks
pp. 1
Using Carbonates
pp. 1
Synthesis by Addition
pp. 1
Use of Carbon Dioxide
pp. 1
Introduction of the α-Hydrogen: Asymmetric Hydrogenation of α,β-Didehydroamino Acid Esters
pp. 1
Coupling of Fischer Carbenes with Acid Chlorides
pp. 1
2,2,6,6-Tetramethylpiperidin-1-oxyl with Sodium Hypochlorite
pp. 1
Nucleophile-Promoted Cleavage
pp. 1
Oxidation with Sodium Tungstate
pp. 1
Activation with 1-Ethoxy-2-silylacetylenes
pp. 1
Wacker Oxidation
pp. 1
Hydroxyacylation and Oxidation of Alkenes
pp. 1
Reduction of Cyclic Anhydrides to Lactones
pp. 1
Oxidative Dimerization of Carboxylic Acids
pp. 1
Reductive Elimination of Vicinal Heteroatom Substituents
pp. 1
Acylation of Bis(trimethylsilyl) Malonate
pp. 1
Thiocarboxylic Acid -Esters
pp. 1
Addition of Alkyl Radicals
pp. 1
[2,3]-Wittig Rearrangements
pp. 1
1,4-Addition of Alcohols
pp. 1
Synthesis of Product Subclass 6
pp. 1
Addition to an α,β-Unsaturated Carboxylic Acid
pp. 1
Opening of Epoxides
pp. 1
Oxidation of 2-Alkylidene Esters
pp. 1
Malonate Esters by Acylation of Malonate Derivatives
pp. 1
Nucleophilic Substitution at the α-Carbon of 2,2-Diheteroatom-Substituted Acetic Acids
pp. 1
Via Tin, Titanium, and Zirconium Enolates
pp. 1
Ring Opening under Basic Conditions
pp. 1
3,3-Disulfanylalkanoic Acid Esters
pp. 1
Stereoselective Birch Reduction of Chiral Pyrrole-2-carboxylates
pp. 1
Addition of Pyrocatechol to Alkyl Penta-2,3-dienoates
pp. 1
Electrocarboxylation of Vinyl Trifluoromethanesulfonates
pp. 1
Using Lead(IV) Acetate
pp. 1
Spiro-λ-selanes from Selenides
pp. 1
Reactions on Solid Support
pp. 1
α-Oxo Acids by Oxidation of Methyl Ketones
pp. 1
Allylic Acyloxylation
pp. 1
Oxidation of Silyl and Stannyl Ethers Using -Bromosuccinimide
pp. 1
Succinic Acid by Hydrolysis of Succinic Anhydride
pp. 1
From 2-Pyran-2-ones
pp. 1
Examples of Industrially Important Enantioselective Hydrogenations
pp. 1
Other Methods
pp. 1
Construction of the Aromatic Ring by Radical Cyclizations of β-Oxo Esters
pp. 1
Introduction of the Side Chain: Sigmatropic Rearrangements
pp. 1
Introduction of the α-Amino Group: Nucleophilic Amination
pp. 1
Organometallic Additions to Chiral Imino Esters
pp. 1
Radical Benzyloxylation
pp. 1
Metal-Complex-Catalyzed α-Alkylation
pp. 1
Oxidation Using Sodium Chlorite or Sodium Hypochlorite
pp. 1
Peroxy Acids, Peroxy Acid Salts, and Peroxy Acid Esters
pp. 1
Enantioselective Michael Addition–Hydrogen Atom Transfer
pp. 1
Elimination from α-Heteroatom-Substituted Alkanoic Acid Esters
pp. 1
Intramolecular Amidomercuration
pp. 1
The Steliou Method
pp. 1
Reaction with Carbanions without Stabilizing Electron-Withdrawing α-Heteroatom Groups
pp. 1
2-Selanylalkanoates
pp. 1
Addition of Organocopper Reagents
pp. 1
Alkylation of Chiral Oxazinones
pp. 1
Formation of Acetals and Hemiacetals
pp. 1
Use of Borohydride Reducing Agents
pp. 1
Carboxylation Using Carbon Dioxide
pp. 1
Via (Acyloxy)phosphorus Compounds
pp. 1
Addition of the Enolates of Acetates to Carbonyl Compounds
pp. 1
Acylation by Carboxylic Acid Halides
pp. 1
Acylation of Methyl Tetrahydro-2-pyran-2-yl Malonate
pp. 1
Transesterification without Catalysis
pp. 1
α-Oxo Acids by Acid Hydrolysis of 2-Hydroxymorpholin-3-ones
pp. 1
Synthesis of the Taxol Side Chain Using the Sharpless Catalytic Asymmetric Aminohydroxylation of Cinnamate Esters
pp. 1
Synthesis from 2,3-Epoxyalkanoic Acid Esters
pp. 1
Addition to Chiral Sulfinimines
pp. 1
Ring Opening of Isoxazolidines
pp. 1
Hydroacyloxylation
pp. 1
Acyl Sulfenamides and Related Compounds
pp. 1
Addition of Acetates to Carbonyl Compounds (via a Formal Zinc Enolate)
pp. 1
Reduction of Anhydrides
pp. 1
Cleavage of Oxalates
pp. 1
Acetylenedicarboxylic Acid by Carboxylation of Organometallic Species
pp. 1
Catalytic Enantioselective Epoxidation of α,β-Unsaturated Esters Using a Lanthanide Lewis Acid Catalyst and -Butyl Hydroperoxide
pp. 1
Addition of Organometallic Reagents to Oxalates
pp. 1
Using Pertrifluoroacetic Acid
pp. 1
With Ruthenium(III) Chloride and Sodium Periodate
pp. 1
()-Acetyl 1,1′-Binaphthyl-2,2′-diyl Phosphite
pp. 1
Acylation of Trimethylsilyl Acetate
pp. 1
Base-Mediated Hydrolysis
pp. 1
Succinic Acids by Oxidative Coupling of Carboxylate Dianions
pp. 1
3,6-Dihydro-2-1,4-oxazin-2-one Alkylation
pp. 1
[2+2] Cycloaddition and the β-Lactam Route to Amino Acids
pp. 1
3-Oxoalkanoic Acid Esters
pp. 1
Using a Catalytic Chiral Titanium Lewis Acid
pp. 1
Synthesis of Product Subclass 15
pp. 1
Addition Reactions
pp. 1
β-Amino Alcohols as Chiral Auxiliaries
pp. 1
With a Heterogeneous Cobalt–Cerium–Ruthenium Catalyst
pp. 1
Synthesis of Product Subclass 2
pp. 1
Ring Opening of Heterocyclic Compounds
pp. 1
In Situ Halogenation of Carboxylate Anions
pp. 1
From O-Alkylated Enol Ethers
pp. 1
Asymmetric Reduction of Hydrazono Lactones Based on Chiral -Aminodihydroindoles
pp. 1
Acetylenedicarboxylic Acid by Oxidative Methods
pp. 1
Zinc(II) Chloride Mediated Reaction of Acid Chlorides with Acylpyridazine Derivatives
pp. 1
α-Alkylation
pp. 1
Carbonyl Homologation by Siloxyalkynes and Alkoxyalkynes
pp. 1
Synthesis of Diacyl Selenides (Selenoanhydrides) and Diacyl Tellurides (Telluroanhydrides)
pp. 1
Hydrolysis of Amides
pp. 1
Conjugate Addition to α,β-Unsaturated Esters
pp. 1
Using Bis(trimethylsilyl) Peroxide
pp. 1
Nucleophilic Substitution at the α-Carbon of Diesters and β-Oxo Esters
pp. 1
Synthesis by Nucleophilic Attack of the α-Carbon of Esters
pp. 1
Malonic Acids by Acylation of Acetic Acid Derivatives
pp. 1
Chiral Pyridoxamine Promoted Asymmetric Reductive Amination of α-Oxo Acids
pp. 1
Metalation/Alkylation of Arene Carboxylates
pp. 1
Homogeneous Catalysis
pp. 1
Hydrolysis of Alk-2-ynoic Acid Esters
pp. 1
Addition of Nitroalkanes to Ethyl Glyoxalate
pp. 1
Conjugate Addition of Terminal Alkynes
pp. 1
Of Simple Alkyl Halides
pp. 1
Using Dioxygen
pp. 1
Direct Esterification of Arenedicarboxylic Acids and Anhydrides Using Alcohols
pp. 1
Synthesis of Product Subclass 5
pp. 1
Succinate Esters by Asymmetric Nucleophilic Addition Using a Chiral Ketone Auxiliary
pp. 1
Intramolecular Rearrangements
pp. 1
Cross-Coupling of Alkenylmercury Halides or Alkenyl Halides with Metal Acetate Salts
pp. 1
Darzens Condensation of α-Bromo Ester Enolates with Sulfinimines
pp. 1
Synthesis from Acid Anhydrides
pp. 1
Oxo/Thioxo Anhydrides Using Hydrogen Disulfide
pp. 1
Oxidation of α-Hydroxy Esters
pp. 1
Pyrolysis of 3-Hydroxy-2-(phenylsulfinyl)alkanoic Acid Esters
pp. 1
Solvolysis of Maleic Anhydride
pp. 1
Diastereoselective Hydrogenation
pp. 1
2,3-Disubstituted 2-Hydroxysuccinates Using a Stoichiometric Chiral Tin Lewis Acid
pp. 1
Catalytic Asymmetric Fluorination of β-Oxo Esters
pp. 1
Allylmalonate Rearrangement
pp. 1
Copper-Catalyzed Alkylations of Imino Esters
pp. 1
Alkylation of 3-Oxoalkanoic Acid Esters
pp. 1
Using Solid-Supported Chlorite Ion
pp. 1
Carbene Additions to Maleic Anhydride Derivatives
pp. 1
Conjugate Addition of Organometallic Reagents
pp. 1
Synthesis of Product Subclass 2
pp. 1
Cobalt(II)-Catalyzed Reaction of Acid Chlorides
pp. 1
Asymmetric Hydrogenation Using Pinene-Based Cyclic Imino Esters as Templates
pp. 1
Nucleophilic Displacement on an α-Substituted Carbonyl Compound
pp. 1
Optically Pure Spiro-λ-sulfanes from Sulfides
pp. 1
Intramolecular Nucleophilic Addition to Epoxides
pp. 1
Conjugate Reduction of α,β-Unsaturated Esters
pp. 1
Alkylation of Chiral Imidazolidinones
pp. 1
2-Alkoxyalkanoates by C—C Bond-Forming Reactions
pp. 1
Silver-Mediated Reactions
pp. 1
Direct Esterification of Arenedicarboxylic Acids Using Pentafluorophenol and ,′-Dicyclohexylcarbodiimide
pp. 1
Malonate Esters by Alkylation of Malonate Derivatives
pp. 1
Synthesis from 2-Bromoalkanoic Acids
pp. 1
Organic Base Mediated Reactions
pp. 1
Hydrolysis of Alkynylbenzotriazoles
pp. 1
Cyclization of 9-Hydroxydecanoic Acid
pp. 1
Addition of Organoborane Reagents
pp. 1
Base-Induced Lactonization
pp. 1
Nucleophilic Displacement of a Hydroxy Group
pp. 1
Construction of the Aromatic Ring by Electrocyclization and Elimination
pp. 1
Synthesis of Product Subclass 1
pp. 1
Oxidation with Manganese
pp. 1
Direct Esterification of Arenedicarboxylic Acids Using Alkyl Halides
pp. 1
Chemical Resolution
pp. 1
Addition of Acetates to Acid Chlorides (via a Titanium Enolate)
pp. 1
Spiro-λ-tellane Synthesis Using the 2-Hydroxy-10-bornyl Group as a Chiral Ligand
pp. 1
With Pyridinium Dichromate
pp. 1
Peroxy Esters of Sulfur, Nitrogen, and Phosphorus
pp. 1
The Yamaguchi Method
pp. 1
Oxidative Hydrolysis
pp. 1
The Mukaiyama Method
pp. 1
Deconjugation
pp. 1
Synthesis via Active Esters
pp. 1
2-Selanylalkanoic Acids
pp. 1
Curtius Rearrangement of α,α-Dialkyl β-Ester Carboxylic Acids
pp. 1
Introduction of the Side Chain: Self-Reproduction of Chirality
pp. 1
Synthesis of Product Subclass 11
pp. 1
Hydrolysis of Esters
pp. 1
Using a Catalytic Chiral Copper Lewis Acid
pp. 1
Synthesis of Amine Carboxylic Acid Salts
pp. 1
Using Preformed Alkynyliodonium Ions
pp. 1
Alkylation of Thiocarboxylic Acids with Alkyl Halides or Related Compounds
pp. 1
Synthesis of α,β-Didehydroamino Esters through Elimination
pp. 1
Using Oxone or Potassium Peroxymonosulfate
pp. 1
Introduction of the Carboxylate Group: Carbene Rearrangement
pp. 1
Oxidation Using Oxone
pp. 1
Metal-Catalyzed Baeyer–Villiger Oxidation
pp. 1
Via Organolithium Reagents
pp. 1
Using a Reformatsky Reagent and a Nitrile
pp. 1
Coupling with Chloroform
pp. 1
2,2,6,6-Tetramethylpiperidin-1-oxyl with (Diacetoxyiodo)benzene
pp. 1
1-(Benzoylperoxy)-2,2,6,6-tetramethylpiperidine by Direct Reaction of Dibenzoyl Peroxide
pp. 1
Introduction of the α-Amino Group: Rearrangement of α,α-Dialkyl-β-carbonyl Carboxylic Acids and Sigmatropic Rearrangements
pp. 1
Asymmetric Addition of Isocyanide to Imines (Ugi Synthesis)
pp. 1
Heterogeneous Catalytic Asymmetric Hydrogenation of 2-Oxoalkanoates
pp. 1
Displacement of Diazonium Groups by Nucleophiles (The Sandmeyer Reaction)
pp. 1
Cleavage of Malonates by Decarboxylation
pp. 1
Metalation and Rearrangement of α,α-Dihalo Ketones (Alkynolate Anions)
pp. 1
Hydrolysis of Ketenes
pp. 1
Coupling of Haloarenes with Propynoic Acid
pp. 1
Using Ozone
pp. 1
Gold-Catalyzed Aldol Reactions
pp. 1
Use of Carbonic Acid Diesters
pp. 1
Reaction of Acid Chlorides and a Disulfide Source
pp. 1
Hydrogenolytic Cleavage of Benzyl Esters
pp. 1
Using -Bromosuccinimide and Alkoxytrimethylsilanes or Alkoxytrialkylstannanes
pp. 1
Electrophilic Amination of Enolates Using a Chiral Catalyst and Azodicarboxylate
pp. 1
From Dibromosuccinates with Sodium Dithionite
pp. 1
Alkene Metathesis
pp. 1
Using Peroxy Acids
pp. 1
With Nickel Peroxide
pp. 1
3-Haloalkanoic Acids
pp. 1
Catalytic Asymmetric Hydrogenation of 2-Oxoalkanoates
pp. 1
Elimination Protocols
pp. 1
Diels–Alder Reaction
pp. 1
Alkoxycarbonylation of Organomagnesium Compounds
pp. 1
Elimination from β-Heteroatom-Substituted Alkanoic Acids
pp. 1
Hetero-Diels–Alder Reactions
pp. 1
Treatment with Tetramethylfluoroformamidinium Hexafluorophosphate
pp. 1
Transition-Metal-Catalyzed Carboxylation with Carbon Monoxide
pp. 1
Synthesis from Carboxylic Acid Esters
pp. 1
Oxidation Using Fuming Nitric Acid
pp. 1
Oxidation of Aldehyde and Ketone Derivatives
pp. 1
Cope Rearrangement of Divinylcyclopropanes
pp. 1
Baeyer–Villiger Oxidation of Bi- and Polycyclic Ketones
pp. 1
Using Pyridinium Tribromide
pp. 1
Chiral Guanidine Catalyzed Strecker Synthesis
Similar content
829
From α-Oxo Sulfoxides: Pummerer Reaction
Authors:
J.-L. Parrain
,
J. Thibonnet
Pummerer Reaction of Amido Sulfoxides
Authors:
R. A. Pilli
,
G. B. Rosso
1-Methoxy-1-(phenylthio)cyclopropanes from olefins via the Pummerer rearrangement
Authors:
M. Bhupathy
,
Theodore Cohen
See all similar