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Review of 'MicroRNAs : An Emerging Player In Autophagy'

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5
A nice review highlight recent advancement in autophagy mediated by miRNAs
Average rating:
    Rated 5 of 5.
Level of importance:
    Rated 5 of 5.
Level of validity:
    Rated 5 of 5.
Level of completeness:
    Rated 5 of 5.
Level of comprehensibility:
    Rated 5 of 5.
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None

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MicroRNAs : An Emerging Player In Autophagy

 yongfei yang,  CHENGYU LIANG (corresponding) (2014)
Autophagy is an evolutionarily conserved self-digestion process for the quality control of intracellular entities in eukaryotes. In the past few years, mounting evidence indicates that microRNAs (miRNAs)-mediated post-transcriptional regulation of gene expression represents an integral part of the autophagy regulatory network and may have a substantial effect on autophagy-related physiological and pathological conditions including cancer. Herein, we examine some of the molecular mechanisms by which microRNAs manipulate the autophagic machinery to maintain cellular homeostasis and their biological outputs during cancer development. A better understanding of interaction between microRNAs and cellular autophagy may ultimately benefit future cancer diagnostic and anticancer therapeutics.
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    Review information

    10.14293/S2199-1006.1.SOR-LIFE.A181CU.v1.RWPXJO

    This work has been published open access under Creative Commons Attribution License CC BY 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Conditions, terms of use and publishing policy can be found at www.scienceopen.com.

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    Review text

    This is a review focused on autophagy mediated by miRNAs. The review is organized based on the processes of autophagy and it is clearly presented. It is a nice review for the people with interested in autophagy.

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