Evaluation of mHealth strategies to optimize adherence and efficacy of Option B+ prevention of mother-to-child HIV transmission: Rationale, design and methods of a 3-armed randomized controlled trial.

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Abstract

Lifelong antiretroviral therapy (ART) (Option B+) is recommended for all HIV-infected pregnant/postpartum women, but high adherence is required to maximize HIV prevention potential and maintain maternal health. Mobile health (mHealth) interventions may provide treatment adherence support for women during, and beyond, the pregnancy and postpartum periods.

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Journal

Journal ID (iso-abbrev): Contemp Clin Trials

Title: Contemporary clinical trials

Publisher: Elsevier BV

ISSN (Electronic): 1559-2030

ISSN (Print): 1551-7144

Publication date (Electronic): Jun 2017

Volume: 57

Affiliations

[1 ] Department of Global Health, University of Washington, Box 359909, Seattle, WA 98195-7236, USA. Electronic address: adrake2@uw.edu.

[2 ] Departments of Global Health and Obstetrics and Gynecology, University of Washington, Box 359909, Seattle, WA 98195-7236, USA. Electronic address: junger@uw.edu.

[3 ] Departments of Global Health and Epidemiology, University of Washington, Box 359909, Seattle, WA 98195-7236, USA. Electronic address: keshet@uw.edu.

[4 ] Department of Research and Programs, Kenyatta National Hospital, PO Box 20723-00202, Nairobi, Kenya. Electronic address: daniel.matemo@gmail.com.

[5 ] Department of Computer Science and Engineering, University of Washington, Box 352350, Seattle, WA 98195-7236, USA. Electronic address: tperrier@cs.washington.edu.

[6 ] Department of Computer Science, University of Cape Town, Room 306, Computer Science Building, Cape Town, South Africa. Electronic address: bderenzi@cs.uct.ac.za.

[7 ] Department of Biostatistics, University of Washington, Box 359909, Seattle, WA 98195-7236, USA. Electronic address: barbrar@uw.edu.

[8 ] Department of Research and Programs, Kenyatta National Hospital, PO Box 20723-00202, Nairobi, Kenya. Electronic address: kinuthia@uw.edu.

[9 ] Departments of Global Health, Medicine, Epidemiology, and Pediatrics, University of Washington, Box 359909, Seattle, WA 98195-7236, USA. Electronic address: gjohn@uw.edu.

Article

Publisher Item ID: S1551-7144(16)30359-7

DOI: 10.1016/j.cct.2017.03.007

PubMed ID: 28315480

SO-VID: c2427c77-3054-43ee-8c5c-e0ac48560d97

History

Keywords: Adherence,Antiretroviral therapy,Pregnancy,Prevention of mother-to-child HIV transmission,SMS,mHealth

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Keywords: Adherence, Antiretroviral therapy, Pregnancy, Prevention of mother-to-child HIV transmission, SMS, mHealth

Evaluation of mHealth strategies to optimize adherence and efficacy of Option B+ prevention of mother-to-child HIV transmission: Rationale, design and methods of a 3-armed randomized controlled trial.

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