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      B-Mode Sonography in Acute Renal Failure

      review-article
      Nephron Clinical Practice
      S. Karger AG
      Obstructive uropathy, Ultrasonography, Acute tubular necrosis, Hydronephrosis

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          Abstract

          B-mode sonography is an extremely useful and cost-effective method to eliminate urinary obstruction as a cause of acute renal failure and should be performed on all patients in whom obstruction is likely or in whom the cause of renal failure is not apparent. The threshold should be reduced in patients with solitary kidneys and sonography is probably indicated in all transplant patients. Sonography has very little utility in the management of other patients with acute renal failure. Although sonographic changes do occur in acute tubular necrosis, they are difficult to detect in the absence of baseline studies and are nonspecific.

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          Most cited references10

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          Correlation of renal histopathology with sonographic findings.

          Judgments about irreversible renal disease are frequently based on the sonographic appearance of the kidneys. However, the sensitivity and specificity of sonography in identifying chronic, irreversible disease have never been determined, and the specific pathologic changes that increase renal cortical echogenicity have not been defined. We retrospectively compared sonographic parameters (length, quantitative echogenicity, cortical thickness, and parenchymal thickness) to biopsy findings of glomerular sclerosis, tubular atrophy, interstitial fibrosis, and interstitial inflammation in 207 patients. Echogenicity showed the strongest correlation with all 4 histologic parameters (r= 0.28-0.35). Renal size was significantly correlated with glomerular sclerosis (r=-0.26) and tubular atrophy (r= 0.20). Parenchymal thickness, but not cortical thickness, correlated with tubular atrophy (r=-0.23). By multivariate analysis, tubular atrophy and interstitial inflammation, but not interstitial fibrosis, were significant determinants of cortical echogenicity. Severe chronic disease (>50% sclerosed glomeruli or a score of 3 out of 5 or greater for tubular atrophy or interstitial fibrosis) was present in 69% and 47% of patients with combined renal length 20 cm, respectively (P= 1.0 (>liver echogenicity) and 1.0. Cortical echogenicity is the sonographic parameter that correlates best with renal histopathology. Although size or echogenicity alone are poor predictors of chronic irreversible disease, the likelihood of treatable disease in small kidneys with increased cortical echogenicity is very low.
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            Sonographic evaluation of renal failure.

            Sonography is a critical component of the evaluation of both acute and chronic renal failure; however, most nephrologists have a limited knowledge of this procedure. The acoustic properties, limited spectrum of pathological changes, and ease of visualization of the kidneys, coupled with the safety, simplicity, and low cost of sonography, make it the modality of choice for renal imaging. This review discusses the basics of sonography as they apply to the kidney and describes the findings encountered in the more common causes of renal failure. Although many sonographic findings are nonspecific, their diagnostic use is greatly enhanced by a familiarity with the clinical presentation and a thorough understanding of renal pathophysiological characteristics. Therefore, nephrologists should be knowledgeable about renal sonography and participate in its interpretation.
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              Ultrasonography in renal transplantation

              Sonography is a simple, inexpensive, and readily available imaging modality that has become an essential component of the management of renal transplantation. It is indicated in almost all patients with acute renal failure and also is useful in the evaluation of pain, infection, and hematuria and the performance of percutaneous biopsy. Although many aspects of sonography are similar in native and transplanted kidneys, there are important differences and problems unique to the renal allograft, which form the basis for this review. The anatomy of renal transplantation and changes that accompany parenchymal disorders are discussed, but particular attention focuses on problems related to the urinary tract, fluid collections, and vascular disorders. By becoming more familiar with transplant sonography, nephrologists will be better able to incorporate this indispensable tool into the care of their patients.
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                Author and article information

                Journal
                NEC
                Nephron Clin Pract
                10.1159/issn.1660-2110
                Nephron Clinical Practice
                S. Karger AG
                978-3-8055-8074-8
                978-3-318-01315-3
                1660-2110
                2006
                March 2006
                10 March 2006
                : 103
                : 2
                : c19-c23
                Affiliations
                Department of Medicine, Renal Division, Emory University School of Medicine, Atlanta, Ga., USA
                Article
                90604 Nephron Clin Pract 2006;103:c19–c23
                10.1159/000090604
                16543751
                299fd42d-173f-42b3-a9ba-4ccbcb332a53
                © 2006 S. Karger AG, Basel

                Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

                History
                Page count
                Figures: 4, References: 23, Pages: 1
                Categories
                Radiologic Imaging

                Cardiovascular Medicine,Nephrology
                Ultrasonography,Obstructive uropathy,Acute tubular necrosis,Hydronephrosis

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