Monocyte-derived dendritic cell recruitment and allergic T(H)2 responses after exposure to diesel particles are CCR2 dependent.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

The inhalation of diesel exhaust particles (DEPs) is associated with increased sensitization toward inhaled allergens. Dendritic cells (DCs) are important mediators in immune regulation. We previously showed that the inhalation of DEPs increased the accumulation of DCs in the lung and enhanced the T(H)2 response in the mediastinal lymph node.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): J. Allergy Clin. Immunol.

Title: The Journal of allergy and clinical immunology

ISSN (Electronic): 1097-6825

ISSN (Print): 0091-6749

Publication date (Electronic): Feb 2012

Volume: 129

Issue: 2

Affiliations

[1 ] Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium. sharen.provoost@UGent.be

Article

Publisher Item ID: S0091-6749(11)01244-9

DOI: 10.1016/j.jaci.2011.07.051

PubMed ID: 21906792

SO-VID: 3c699918-1411-412a-b512-d0498f2af4ab

History

Data availability:

Comments

Comment on this article

scite_

Cited by 19

See all cited by

- Version 1