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      Severe osteomalacia presenting with multiple vertebral fractures: a case report and review of the literature.

      Endocrine
      Female, Humans, Magnetic Resonance Imaging, Middle Aged, Osteomalacia, complications, pathology, Spinal Fractures, etiology, Sunlight, Vitamin D Deficiency

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          Abstract

          Adequate exposure to sunlight and fortification of dairy products with vitamin D have eliminated vitamin D deficiency secondary to inadequate endogenous production or nutrition in the majority of countries. Insufficient vitamin D intake secondary to using unfortified foods and social customs (such as avoiding sun exposure), however, contribute to the development of disease. Poor diet, a lack of sun exposure, and the age related decline in the dermal synthesis of 7-dehydrocholesterol are among the factors that predispose to vitamin D deficiency and consequent bone disease. Here, we present a case of severe osteomalacia presenting with multiple vertebral fractures due to poor diet and a lack of exposure to sunlight.

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          Author and article information

          Journal
          19543841
          10.1007/s12020-009-9209-8

          Chemistry
          Female,Humans,Magnetic Resonance Imaging,Middle Aged,Osteomalacia,complications,pathology,Spinal Fractures,etiology,Sunlight,Vitamin D Deficiency

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