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MicroRNA history: discovery, recent applications, and next frontiers.

Author(s): Maria Almeida, Rui Reis, George A. Calin

Publication date: 2011-12-01

Keywords: Biological Markers, metabolism, History, 20th Century, History, 21st Century, Humans, MicroRNAs, genetics, history, Neoplasms, diagnosis

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Abstract

Since 1993, when the first small non-coding RNA was identified, our knowledge about microRNAs has grown exponentially. In this review, we focus on the main progress in this field and discuss the most important findings under a historical perspective. In addition, we examine microRNAs as markers of disease diagnosis and prognosis, and as new therapeutic targets. Copyright Â© 2011 Elsevier B.V. All rights reserved.

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PubMed ID:: 21458467

DOI:: 10.1016/j.mrfmmm.2011.03.009

ScienceOpen disciplines: Chemistry

Keywords: Biological Markers,metabolism,History, 20th Century,History, 21st Century,Humans,MicroRNAs,genetics,history,Neoplasms,diagnosis

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ScienceOpen disciplines: Chemistry

Keywords: Biological Markers, metabolism, History, 20th Century, History, 21st Century, Humans, MicroRNAs, genetics, history, Neoplasms, diagnosis

MicroRNA history: discovery, recent applications, and next frontiers.

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