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Abstract
Precise localization of sulco-gyral structures of the human cerebral cortex is important
for the interpretation of morpho-functional data, but requires anatomical expertise
and is time consuming because of the brain's geometric complexity. Software developed
to automatically identify sulco-gyral structures has improved substantially as a result
of techniques providing topologically correct reconstructions permitting inflated
views of the human brain. Here we describe a complete parcellation of the cortical
surface using standard internationally accepted nomenclature and criteria. This parcellation
is available in the FreeSurfer package. First, a computer-assisted hand parcellation
classified each vertex as sulcal or gyral, and these were then subparcellated into
74 labels per hemisphere. Twelve datasets were used to develop rules and algorithms
(reported here) that produced labels consistent with anatomical rules as well as automated
computational parcellation. The final parcellation was used to build an atlas for
automatically labeling the whole cerebral cortex. This atlas was used to label an
additional 12 datasets, which were found to have good concordance with manual labels.
This paper presents a precisely defined method for automatically labeling the cortical
surface in standard terminology.
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