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      Prevalence of food sensitization and probable food allergy among adults in India: the EuroPrevall INCO study.

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          Abstract

          Data are lacking regarding the prevalence of food sensitization and probable food allergy among general population in India. We report the prevalence of sensitization and probable food allergy to 24 common foods among adults from general population in Karnataka, South India.

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          Epidemiology of food allergy.

          Scott H. Sicherer (2011)
          Adverse reactions to foods can occur for a variety of reasons, but a food allergy is caused by a specific immune response. Challenges to determine the prevalence of food allergy include misclassification, biased participation, lack of simple diagnostic tests, rapid evolution of disease, large numbers of potential triggers, and varied clinical phenotypes. Nonetheless, it is clear that this is a common disorder, with studies suggesting a cumulative prevalence of 3% to 6%, representing a significant impact on quality of life and costs. The inclusion of mild reactions to fruits and vegetables could result in calculation of prevalence exceeding 10% in some regions. There are data from numerous studies to suggest an increase in prevalence, but methodologic concerns warrant caution. Prevalence varies by age, geographic location, and possibly race/ethnicity. Many childhood food allergies resolve. Population-based epidemiologic studies have generated numerous novel theories regarding risks, including modifiable factors such as components of the maternal and infant diet, obesity, and the timing of food introduction. Recent and ongoing studies provide insights on risk factors, prevalence, and natural course that may inform clinical trials to improve diagnosis, prevention, and treatment. Copyright © 2011 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.
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            The epidemiology of food allergy in Europe: a systematic review and meta-analysis.

            B I Nwaru, L Hickstein, S Panesar … (2014)
            Food allergy (FA) is an important atopic disease although its precise burden is unclear. This systematic review aimed to provide recent, up-to-date data on the incidence, prevalence, time trends, and risk and prognostic factors for FA in Europe. We searched four electronic databases, covering studies published from 1 January 2000 to 30 September 2012. Two independent reviewers appraised the studies and qualified the risk of bias using the Critical Appraisal Skills Programme tool. Seventy-five eligible articles (comprising 56 primary studies) were included in a narrative synthesis, and 30 studies in a random-effects meta-analysis. Most of the studies were graded as at moderate risk of bias. The pooled lifetime and point prevalence of self-reported FA were 17.3% (95% CI: 17.0-17.6) and 5.9% (95% CI: 5.7-6.1), respectively. The point prevalence of sensitization to ≥1 food as assessed by specific IgE was 10.1% (95% CI: 9.4-10.8) and skin prick test 2.7% (95% CI: 2.4-3.0), food challenge positivity 0.9% (95% CI: 0.8-1.1). While the incidence of FA appeared stable over time, there was some evidence that the prevalence may be increasing. There were no consistent risk or prognostic factors for the development or resolution of FA identified, but sex, age, country of residence, familial atopic history, and the presence of other allergic diseases seem to be important. Food allergy is a significant clinical problem in Europe. The evidence base in this area would benefit from additional studies using standardized, rigorous methodology; data are particularly required from Eastern and Southern Europe. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
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              The European Community Respiratory Health Survey

              P.G.J. Burney, C Luczynska, S. Chinn … (1994)
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                Author and article information

                Journal
                Journal ID (iso-abbrev): Allergy
                Title: Allergy
                Publisher: Wiley
                ISSN (Electronic): 1398-9995
                ISSN (Print): 0105-4538
                Publication date (Electronic): July 2016
                Volume: 71
                Issue: 7
                Affiliations
                [1 ] Department of Allergy, Allergy Asthma Associates, Mysore, Karnataka, India.
                [2 ] Department of TB and Respiratory Medicine, JSS Medical College and Hospital, JSS University, Mysore, Karnataka, India.
                [3 ] Department of Pediatrics and School of Public Health, Chinese University of Hong Kong, Shatin, NT, Hong Kong, China.
                [4 ] Department of Faculty Pediatrics, Siberian State Medical University, Tomsk, Russia.
                [5 ] Department of Respiratory Epidemiology and Public Health, National Heart and Lung Institute, Imperial College London, London, UK.
                [6 ] Allergy Department, Hospital Clinico San Carlos, IdISSC, Madrid, Spain.
                [7 ] Respiratory and Allergy Centre, Institute of Inflammation and Repair, Manchester Institute of Biotechnology, The University of Manchester, Manchester, UK.
                [8 ] Department of Experimental Immunology and Department of Otorhinolaryngology, Academic Medical Center, Amsterdam, the Netherlands.
                [9 ] Department of Parasitology, Leiden University Medical Center, Leiden, the Netherlands.
                Article
                DOI: 10.1111/all.12868
                PubMed ID: 27297800
                SO-VID: 5fba2b69-91b1-4480-a443-ab68cab3b320
                History

                Keywords: Food sensitization,Prevalence,EuroPrevall,aeroallergen sensitization,IgE,probable food allergy,India,Adults
                Data availability:
                Keywords: Food sensitization, Prevalence, EuroPrevall, aeroallergen sensitization, IgE, probable food allergy, India, Adults

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