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      ANÁLISE DE DIFERENTES MÉTODOS DE AVALIAÇÃO DO ESTADO NUTRICIONAL DE PACIENTES EM HEMODIÁLISE

      Revista Cuidarte
      Programa de Enfermería, Facultad de Ciencias de la Salud, Universidad de Santander UDES
      Avaliação Nutricional, Desnutrição, Hemodiálise, Insuficiencia Renal Crónica, Enfermedad Renal Crónica, Nutrition Assessment, Malnutrition, Renal Dialysis, Renal Insufficiency Chronic, Kidney Failure Chronic, Insuficiência Renal Crônica, Doença Renal Crônica, Evaluación Nutricional, Desnutrición, Hemodiálisis

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          Abstract

          Introdução: O paciente em diálise deve ser avaliado nutricionalmente e monitorado periodicamente desde o início do tratamento dialítico, possibilitando melhores propostas de intervenções e adequações dietéticas eficazes. Objetivo: Comparar estado nutricional de pacientes com Doença Renal Crônica em hemodiálise, classificados entre desnutridos e não desnutridos, por diferentes parâmetros clínicos, antropométricos, laboratoriais e verificar o nível de concordância dessas formas avaliativas. Materiais e Métodos: Estudo transversal, realizado em 2010, com 90 pacientes de uma clínica de diálise em Belo Horizonte/MG. Foram coletados dados pessoais, socioeconômicos, nutricionais, clínicos, bioquímicos e antropométricos. Resultados e Discussão: Houve variação de 12,2% a 86,7% de indivíduos desnutridos conforme diferentes parâmetros avaliativos. Nas análises antropométricas, homens apresentaram pregas cutâneas menores que mulheres. Quanto à circunferência muscular do braço, quase 40% apresentaram classificação de desnutrição, sendo aproximadamente 30% destes do sexo masculino. Os valores médios Índice de Massa Corporal encontraram-se dentro da classificação de normalidade. Quanto à ingestão calórica e ingestão protéica, as proporções de pacientes com ingestão inferior ao desejado foram de 86,7% e 57,8% respectivamente. A média dos valores de albumina foi de 3,9g/dL e a classificação de desnutrição variou entre 25,6% e 50% dependendo da referência utilizada. Conclusões: A grande variação de classificação dos pacientes como desnutridos obtida, sugere a necessidade de padronização de rotinas, observação e acompanhamento cautelosos das referências e a necessidade de comitês de avaliação para determinação de novos pontos de corte para melhor classificação nutricional desta população.

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          Most cited references107

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          Practical statistics for medical research. Douglas G. Altman, Chapman and Hall, London, 1991. No. of pages: 611. Price: £32.00

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            A malnutrition-inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients.

            Malnutrition inflammation complex syndrome (MICS) occurs commonly in maintenance hemodialysis (MHD) patients and may correlate with increased morbidity and mortality. An optimal, comprehensive, quantitative system that assesses MICS could be a useful measure of clinical status and may be a predictor of outcome in MHD patients. We therefore attempted to develop and validate such an instrument, comparing it with conventional measures of nutrition and inflammation, as well as prospective hospitalization and mortality. Using components of the conventional Subjective Global Assessment (SGA), a semiquantitative scale with three severity levels, the Dialysis Malnutrition Score (DMS), a fully quantitative scoring system consisting of 7 SGA components, with total score ranging between 7 (normal) and 35 (severely malnourished), was recently developed. To improve the DMS, we added three new elements to the 7 DMS components: body mass index, serum albumin level, and total iron-binding capacity to represent serum transferrin level. This new comprehensive Malnutrition-Inflammation Score (MIS) has 10 components, each with four levels of severity, from 0 (normal) to 3 (very severe). The sum of all 10 MIS components ranges from 0 to 30, denoting increasing degree of severity. These scores were compared with anthropometric measurements, near-infrared-measured body fat percentage, laboratory measures that included serum C-reactive protein (CRP), and 12-month prospective hospitalization and mortality rates. Eighty-three outpatients (44 men, 39 women; age, 59 +/- 15 years) on MHD therapy for at least 3 months (43 +/- 33 months) were evaluated at the beginning of this study and followed up for 1 year. The SGA, DMS, and MIS were assessed simultaneously on all patients by a trained physician. Case-mix-adjusted correlation coefficients for the MIS were significant for hospitalization days (r = 0.45; P < 0.001) and frequency of hospitalization (r = 0.46; P < 0.001). Compared with the SGA and DMS, most pertinent correlation coefficients were stronger with the MIS. The MIS, but not the SGA or DMS, correlated significantly with creatinine level, hematocrit, and CRP level. During the 12-month follow-up, 9 patients died and 6 patients left the cohort. The Cox proportional hazard-calculated relative risk for death for each 10-unit increase in the MIS was 10.43 (95% confidence interval, 2.28 to 47.64; P = 0.002). The MIS was superior to its components or different subversions for predicting mortality. The MIS appears to be a comprehensive scoring system with significant associations with prospective hospitalization and mortality, as well as measures of nutrition, inflammation, and anemia in MHD patients. The MIS may be superior to the conventional SGA and the DMS, as well as to individual laboratory values, as a predictor of dialysis outcome and an indicator of MICS.
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              Practical Statistics for Medical Research

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