24
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Neural ensembles in CA3 transiently encode paths forward of the animal at a decision point.

      The Journal of neuroscience : the official journal of the Society for Neuroscience
      Action Potentials, physiology, Animals, Choice Behavior, Decision Making, Hippocampus, Male, Maze Learning, Nerve Net, Neural Pathways, physiopathology, Rats, Rats, Inbred BN, Rats, Inbred F344, Spatial Behavior, Time Factors

      Read this article at

      ScienceOpenPublisherPubMed
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Neural ensembles were recorded from the CA3 region of rats running on T-based decision tasks. Examination of neural representations of space at fast time scales revealed a transient but repeatable phenomenon as rats made a decision: the location reconstructed from the neural ensemble swept forward, first down one path and then the other. Estimated representations were coherent and preferentially swept ahead of the animal rather than behind the animal, implying it represented future possibilities rather than recently traveled paths. Similar phenomena occurred at other important decisions (such as in recovery from an error). Local field potentials from these sites contained pronounced theta and gamma frequencies, but no sharp wave frequencies. Forward-shifted spatial representations were influenced by task demands and experience. These data suggest that the hippocampus does not represent space as a passive computation, but rather that hippocampal spatial processing is an active process likely regulated by cognitive mechanisms.

          Related collections

          Author and article information

          Comments

          Comment on this article