Topological defects, such as domain walls and vortices, have long fascinated physicists. A novel twist is added in quantum systems like the B-phase of superfluid helium He\(_3\), where vortices are associated with low energy excitations in the cores. Similarly, cosmic strings may be tied to propagating fermion modes. Can analogous phenomena occur in crystalline solids that host a plethora of topological defects? Here we show that indeed dislocation lines are associated with one dimensional fermionic excitations in a `topological insulator', a novel band insulator believed to be realized in the bulk material Bi\(_{0.9}\)Sb\(_{0.1}\). In contrast to fermionic excitations in a regular quantum wire, these modes are topologically protected like the helical edge states of the quantum spin-Hall insulator, and not scattered by disorder. Since dislocations are ubiquitous in real materials, these excitations could dominate spin and charge transport in topological insulators. Our results provide a novel route to creating a potentially ideal quantum wire in a bulk solid.