Rationale and design of POPular-TAVI: antiPlatelet therapy fOr Patients undergoing Transcatheter Aortic Valve Implantation.

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Abstract

Despite improving experience and techniques, ischemic and bleeding complications after transcatheter aortic valve implantation (TAVI) remain prevalent and impair survival. Current guidelines recommend the temporary addition of clopidogrel in the initial period after TAVI to prevent thromboembolic events. However, explorative studies suggest that this is associated with a higher rate of major bleeding without a decrease in thromboembolic complications.

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Journal

Journal ID (iso-abbrev): Am. Heart J.

Title: American heart journal

Publisher: Elsevier BV

ISSN (Electronic): 1097-6744

ISSN (Print): 0002-8703

Publication date (Electronic): Mar 2016

Volume: 173

Affiliations

[1 ] Department of Cardiology, St Antonius Hospital, Nieuwegein, the Netherlands.

[2 ] Department of Cardiology, Academic Medical Centre, Amsterdam, the Netherlands.

[3 ] Department of Cardiology, Isala Klinieken, Zwolle, the Netherlands.

[4 ] Department of Cardiology, University Medical Centre St Radboud, Nijmegen, the Netherlands.

[5 ] Department of Cardiology, Medical University Centre, Maastricht, the Netherlands.

[6 ] Department of Cardiology, University Medical Centre, Groningen, the Netherlands.

[7 ] Department of Cardiology, Amphia Hospital, Breda, the Netherlands.

[8 ] Department of Clinical Pharmacy, St Antonius Hospital, Nieuwegein, the Netherlands.

[9 ] Department of Cardiology, University Medical Centre, Leiden, the Netherlands.

[10 ] Department of Cardiac Surgery, University of Verona, Verona, Italy.

[11 ] Department of Cardiology, Hôpital Universitaire Pitié Salpêtrière, Paris, France.

[12 ] Department of Cardiovascular Surgery, UniversitätsSpital Zürich, Zürich, Switzerland.

[13 ] Department of Cardiology, Università Vita-Salute San Raffaele Milano, Milan, Italy.

[14 ] Department of Cardiology, Wilhelminenspital, Vienna, Austria.

[15 ] Department of Cardiology, University Medical Centre Utrecht, Utrecht, the Netherlands.

[16 ] Department of Cardiology, St Antonius Hospital, Nieuwegein, the Netherlands. Electronic address: j.ten.berg@antoniusziekenhuis.nl.

Article

Publisher Item ID: S0002-8703(15)00665-1

DOI: 10.1016/j.ahj.2015.11.008

PubMed ID: 26920599

SO-VID: ccdc7e9d-ef3c-4ae7-852b-04746a16b534

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