Methylation profiles of IL33 and CCL26 in bronchial epithelial cells are associated with asthma.

Larouche, Miriam; Gagné-Ouellet, Valérie; Boucher-Lafleur, Anne-Marie; Larose, Marie-Chantal; Plante, Sophie; Madore, Anne-Marie; Laviolette, Michel; Flamand, Nicolas; Chakir, Jamila; Laprise, Catherine

doi:10.2217/epi-2018-0044

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Methylation profiles of IL33 and CCL26 in bronchial epithelial cells are associated with asthma.

Author(s): Miriam Larouche ¹ , Valérie Gagné-Ouellet ¹ , Anne-Marie Boucher-Lafleur ¹ , Marie-Chantal Larose ² , Sophie Plante ² , Anne-Marie Madore ¹ , Michel Laviolette ² , Nicolas Flamand ² , Jamila Chakir ² , Catherine Laprise ¹ ^, ³

Publication date (Electronic): Dec 2018

Journal: Epigenomics

Publisher: Future Medicine Ltd

Keywords: , DNA methylation, bronchial epithelial cell, eosinophil, gene expression

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Abstract

This study aimed to characterize DNA methylation (DNA-me) in promoter region of IL33, IL1RL1 and CCL26 in asthma and their impacts on transcriptional activity in bronchial epithelial cells (BECs).

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Journal ID (iso-abbrev): Epigenomics

Title: Epigenomics

Publisher: Future Medicine Ltd

ISSN (Electronic): 1750-192X

ISSN (Print): 1750-192X

Publication date (Electronic): Dec 2018

Volume: 10

Issue: 12

Affiliations

[1 ] Département des sciences fondamentales, Université du Québec à Chicoutimi, Saguenay, QC G7H 2B1, Canada.

[2 ] Centre de recherche, Institut universitaire de cardiologie et de pneumologie de Québec, Département de médecine, Faculté de médecine, Université Laval, Québec City, QC G1V 4G5, Canada.

[3 ] Centre intersectoriel en santé durable, Université du Québec à Chicoutimi, Saguenay, QC G7H 2B1, Canada.

Article

DOI: 10.2217/epi-2018-0044

PubMed ID: 30468398

SO-VID: 0170d0c5-87de-4515-8a92-372b669b56a4

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Keywords: DNA methylation,bronchial epithelial cell,eosinophil,gene expression

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Keywords: DNA methylation, bronchial epithelial cell, eosinophil, gene expression

Methylation profiles of IL33 and CCL26 in bronchial epithelial cells are associated with asthma.

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