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      Is Open Access

      Long-term viability of allogenic donor stroma

      case-report

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          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          We report the clinical history and histopathology of the longest known postoperative course of a myopic cornea lenticule implanted via epikeratoplasty that also had been subjected to excimer laser and mitomycin. Despite the mechanical and photochemical processes the allogenic cornea stroma had sustained, it is notable that it retained structural integrity and clarity. This report affirms the potential long-term clarity and resilience of allogenic stromal cornea and supports its use as a potential stabilizing option in cornea allogenic intrastromal ring segments for keratoconus and variations thereof for other cornea disorders.

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          Corneal Allogenic Intrastromal Ring Segments (CAIRS) Combined With Corneal Cross-linking for Keratoconus

          Soosan Jacob, Shaila R. Patel, Amar Agarwal … (2018)
          Article 0 comments Cited 23 times – based on 0 reviews     Review now
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            Long-term outcome of epikeratophakia

            Mark Cahill, Patrick Condon, Michael O'Keefe (1999)
            Article 0 comments Cited 4 times – based on 0 reviews     Review now
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              Epikeratophakia for keratoconus. The nationwide study.

              H Kaufman, R H Keates, Fiona McDonald … (1986)
              The nationwide study of epikeratophakia for the treatment of keratoconus involved 69 surgeons in the United States; they operated on 177 eyes as of Dec 31, 1985. In this first report, the results from 35 surgeons involving 82 cases with 30 or more days of follow-up after suture removal are described. In all but two patients, uncorrected visual acuity improved; 17 patients showed improvement of three Snellen lines, and 38 patients showed improvement of four or more lines. The majority of patients' vision returned to within one line of their best corrected acuity; in 78% it was 20/40 or better postoperatively. Eight patients needed no postoperative overrefraction at all. The mean flattening by keratometry readings was 9.36 diopters, and the mean decrease in myopia in terms of spherical equivalent was 5.26 D. No significant changes in intraocular pressure or endothelial cell counts were noted. Some advantages of epikeratophakia for keratoconus over the traditional penetrating keratoplasty include the lack of serious, vision-threatening complications or permanent vision loss, the reversible nature of the surgery, and the absence of potential immunogenic rejection phenomena.
              Article 0 comments Cited 4 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): Indian J Ophthalmol
                Journal ID (iso-abbrev): Indian J Ophthalmol
                Journal ID (publisher-id): IJO
                Title: Indian Journal of Ophthalmology
                Publisher: Wolters Kluwer - Medknow (India )
                ISSN (Print): 0301-4738
                ISSN (Electronic): 1998-3689
                Publication date (Print): December 2020
                Publication date (Electronic): 23 November 2020
                Volume: 68
                Issue: 12
                Pages: 3057-3059
                Affiliations
                [1 ]Department of Ophthalmology, Minneapolis VA Health Care System, Minneapolis, MN, USA
                [2 ]Department of Ophthalmology, University of Minnesota, Minneapolis, MN, USA
                [3 ]University of Minnesota Medical School, Minneapolis, MN, USA
                [4 ]Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA
                [5 ]Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA
                Author notes
                Correspondence to: Mr. Christopher Santilli, 2085 Royale Dr., Eagan, MN - 55122, USA. E-mail: santi145@ 123456umn.edu
                Article
                Publisher ID: IJO-68-3057
                DOI: 10.4103/ijo.IJO_1008_20
                PMC ID: 7856995
                PubMed ID: 33229705
                SO-VID: 03a2d6a2-2ffd-4080-a465-67ea79a0e2ab
                Copyright © Copyright: © 2020 Indian Journal of Ophthalmology
                License:

                This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

                History
                Date received : 15 April 2020
                Date revision received : 05 July 2020
                Date accepted : 11 July 2020
                Categories
                Subject: Case Reports

                ScienceOpen disciplines: Ophthalmology & Optometry
                Keywords: allogenic cornea,epikeratophakia,epikeratoplasty,intrastromal implant,record-holding
                Data availability:
                ScienceOpen disciplines: Ophthalmology & Optometry
                Keywords: allogenic cornea, epikeratophakia, epikeratoplasty, intrastromal implant, record-holding

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