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      Clustering of chronic non-communicable disease risk factors among selected Asian populations: levels and determinants

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          Abstract

          Background

          The major chronic non-communicable diseases (NCDs) operate through a cluster of common risk factors, whose presence or absence determines not only the occurrence and severity of the disease, but also informs treatment approaches. Primary prevention based on mitigation of these common risk factors through population-based programmes is the most cost-effective approach to contain the emerging epidemic of chronic NCDs.

          Objectives

          This study was conducted to explore the extent of risk factors clustering for the major chronic NCDs and its determinants in nine INDEPTH Health and Demographic Surveillance System (HDSS) sites of five Asian countries.

          Design

          Data originated from a multi-site chronic NCD risk factor prevalence survey conducted in 2005. This cross-sectional survey used a standardised questionnaire developed by the WHO to collect core data on common risk factors such as tobacco use, intake of fruits and vegetables, physical inactivity, blood pressure levels, and body mass index. Respondents included randomly selected sample of adults (25–64 years) living in nine rural HDSS sites in Bangladesh, India, Indonesia, Thailand, and Vietnam.

          Results

          Findings revealed a substantial proportion (>70%) of these largely rural populations having three or more risk factors for chronic NCDs. Chronic NCD risk factors clustering was associated with increasing age, being male, and higher educational achievements. Differences were noted among the different sites, both between and within country.

          Conclusions

          Since there is an extensive clustering of risk factors for the chronic NCDs in the populations studied, the interventions also need to be based on a comprehensive approach rather than on a single factor to forestall its cumulative effects which occur over time. This can work best if it is integrated within the primary health care system and the HDSS can be an invaluable epidemiological resource in this endeavor.

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          Most cited references38

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          The burden of non communicable diseases in developing countries

          Background By the dawn of the third millennium, non communicable diseases are sweeping the entire globe, with an increasing trend in developing countries where, the transition imposes more constraints to deal with the double burden of infective and non-infective diseases in a poor environment characterised by ill-health systems. By 2020, it is predicted that these diseases will be causing seven out of every 10 deaths in developing countries. Many of the non communicable diseases can be prevented by tackling associated risk factors. Methods Data from national registries and international organisms are collected, compared and analyzed. The focus is made on the growing burden of non communicable diseases in developing countries. Results Among non communicable diseases, special attention is devoted to cardiovascular diseases, diabetes, cancer and chronic pulmonary diseases. Their burden is affecting countries worldwide but with a growing trend in developing countries. Preventive strategies must take into account the growing trend of risk factors correlated to these diseases. Conclusion Non communicable diseases are more and more prevalent in developing countries where they double the burden of infective diseases. If the present trend is maintained, the health systems in low-and middle-income countries will be unable to support the burden of disease. Prominent causes for heart disease, diabetes, cancer and pulmonary diseases can be prevented but urgent (preventive) actions are needed and efficient strategies should deal seriously with risk factors like smoking, alcohol, physical inactivity and western diet.
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            Chronic disease prevention: health effects and financial costs of strategies to reduce salt intake and control tobacco use.

            In 2005, WHO set a global goal to reduce rates of death from chronic (non-communicable) disease by an additional 2% every year. To this end, we investigated how many deaths could potentially be averted over 10 years by implementation of selected population-based interventions, and calculated the financial costs of their implementation. We selected two interventions: to reduce salt intake in the population by 15% and to implement four key elements of the WHO Framework Convention on Tobacco Control (FCTC). We used methods from the WHO Comparative Risk Assessment project to estimate shifts in the distribution of risk factors associated with salt intake and tobacco use, and to model the effects on chronic disease mortality for 23 countries that account for 80% of chronic disease burden in the developing world. We showed that, over 10 years (2006-2015), 13.8 million deaths could be averted by implementation of these interventions, at a cost of less than US$0.40 per person per year in low-income and lower middle-income countries, and US$0.50-1.00 per person per year in upper middle-income countries (as of 2005). These two population-based intervention strategies could therefore substantially reduce mortality from chronic diseases, and make a major (and affordable) contribution towards achievement of the global goal to prevent and control chronic diseases.
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              Non-communicable diseases in low- and middle-income countries: context, determinants and health policy.

              The rise of non-communicable diseases and their impact in low- and middle-income countries has gained increased attention in recent years. However, the explanation for this rise is mostly an extrapolation from the history of high-income countries whose experience differed from the development processes affecting today's low- and middle-income countries. This review appraises these differences in context to gain a better understanding of the epidemic of non-communicable diseases in low- and middle-income countries. Theories of developmental and degenerative determinants of non-communicable diseases are discussed to provide strong evidence for a causally informed approach to prevention. Health policies for non-communicable diseases are considered in terms of interventions to reduce population risk and individual susceptibility and the research needs for low- and middle-income countries are discussed. Finally, the need for health system reform to strengthen primary care is highlighted as a major policy to reduce the toll of this rising epidemic.
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                Author and article information

                Journal
                Glob Health Action
                GHA
                Global Health Action
                CoAction Publishing
                1654-9716
                1654-9880
                28 September 2009
                2009
                : 2
                : 10.3402/gha.v2i0.1986
                Affiliations
                [1 ]WATCH Health and Demographic Surveillance System, Bangladesh
                [2 ]Matlab Health and Demographic Surveillance System, Bangladesh
                [3 ]AMK Health and Demographic Surveillance System, Bangladesh
                [4 ]Vadu Health and Demographic Surveillance System, India
                [5 ]Purworejo Health and Demographic Surveillance System, Indonesia
                [6 ]Kanchanaburi Health and Demographic Surveillance System, Thailand
                [7 ]Filabavi Health and Demographic Surveillance System, Vietnam
                [8 ]Chililab Health and Demographic Surveillance System, Vietnam
                Author notes
                [* ] Syed Masud Ahmed, Research and Evaluation Division, BRAC, BRAC Centre 75, Mohakhali, Dhaka-1212, Bangladesh. Email: ahmed.sm@ 123456brac.net
                Article
                GHA-2-1986
                10.3402/gha.v2i0.1986
                2785214
                20027260
                042b6277-ab96-4247-94c8-eb2bcbb324f2
                © 2009 Syed Masud Ahmed et al.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 06 May 2009
                : 30 June 2009
                : 16 July 2009
                Categories
                Supplement 1, 2009
                NCD Supplement

                Health & Social care
                indepth,asia,chronic ncds,risk factors surveillance,clustering,who steps
                Health & Social care
                indepth, asia, chronic ncds, risk factors surveillance, clustering, who steps

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