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Enhancement of functional connectivity, working memory and inhibitory control on multi-modal brain MR imaging with Rifaximin in Cirrhosis: implications for the gut-liver-brain axis.
Vishwadeep Ahluwalia
1 ,
James B Wade ,
Douglas M Heuman ,
Thomas A Hammeke ,
Arun J Sanyal ,
Richard K Sterling ,
R Todd Stravitz ,
Velimir Luketic ,
Mohammad S Siddiqui ,
Puneet Puri ,
Michael Fuchs ,
Micheal J Lennon ,
Kenneth A Kraft ,
HoChong Gilles ,
Melanie B White ,
Nicole A Noble ,
Jasmohan S Bajaj
Dec 2014
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Abstract
Minimal hepatic encephalopathy (MHE) impairs daily functioning in cirrhosis, but its functional brain impact is not completely understood. To evaluate the effect of rifaximin, a gut-specific antibiotic, on the gut-liver-brain axis in MHE.