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Abstract
Update of the 2002 U.S. Preventive Services Task Force (USPSTF) recommendation statement
on screening for colorectal cancer.
To update its recommendation, the USPSTF commissioned 2 studies: 1) a targeted systematic
evidence review on 4 selected questions relating to test characteristics and benefits
and harms of screening technologies, and 2) a decision analytic modeling analysis
using population modeling techniques to compare the expected health outcomes and resource
requirements of available screening modalities when used in a programmatic way over
time.
The USPSTF recommends screening for colorectal cancer using fecal occult blood testing,
sigmoidoscopy, or colonoscopy in adults, beginning at age 50 years and continuing
until age 75 years. The risks and benefits of these screening methods vary. (A recommendation).
The USPSTF recommends against routine screening for colorectal cancer in adults 76
to 85 years of age. There may be considerations that support colorectal cancer screening
in an individual patient. (C recommendation). The USPSTF recommends against screening
for colorectal cancer in adults older than age 85 years. (D recommendation). The USPSTF
concludes that the evidence is insufficient to assess the benefits and harms of computed
tomographic colonography and fecal DNA testing as screening modalities for colorectal
cancer. (I statement).