Association of CASP7 polymorphisms and survival of patients with non-small cell lung cancer with platinum-based chemotherapy treatment.

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Abstract

CASP7 plays a crucial role in cancer development and chemotherapy efficacy. We, therefore, explored whether single nucleotide polymorphisms (SNPs) of the CASP7 gene can modulate outcomes of patients with advanced non-small cell lung cancer (NSCLC) treated with first-line platinum-based chemotherapy.

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Journal

Journal ID (iso-abbrev): Chest

Title: Chest

Publisher: American College of Chest Physicians

ISSN (Electronic): 1931-3543

ISSN (Print): 0012-3692

Publication date (Electronic): Sep 2012

Volume: 142

Issue: 3

Affiliations

[1 ] State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Fudan Taizhou Institute of Health Sciences, Fudan University, Shanghai, China.

[2 ] School of Life Science, East China Normal University, Shanghai, China.

[3 ] Department of Respiratory Disease, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China; Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX.

[4 ] Department of Respiratory Disease, Shanghai Chest Hospital, Shanghai Jiaotong University, Shanghai, China.

[5 ] Department of Respiratory Disease, Renji Hospital, Shanghai Jiaotong University, Shanghai, China; Department of Respiratory Disease, Changzheng Hospital, Second Military Medical University, Shanghai, China.

[6 ] State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences and Fudan Taizhou Institute of Health Sciences, Fudan University, Shanghai, China. Electronic address: drlu@fudan.edu.cn.

[7 ] Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX.

Article

Publisher Item ID: S0012-3692(12)60512-1

DOI: 10.1378/chest.11-2522

PubMed ID: 22441531

SO-VID: 07fe6d8c-1294-4b92-a3a9-78c18da518d9

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